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How have the rules for transporting Wegovy injections changed?

How have the rules for transporting Wegovy injections changed?

The MHRA (Medicines & Healthcare products Regulatory Agency) allows Wegovy FlexTouch pens to remain unrefrigerated at temperatures below 30°C for up to 48 hours during transport. This won’t affect the medicine, and it will remain effective. After 48 hours, the pen should be placed in the fridge. Wegovy is the first weight loss injection that doesn’t require cold-chain transport.

Sanjeda Chowdhury
Medically reviewed by
Sanjeda Chowdhury, Superintendent Pharmacist + Independent Prescriber
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Reviewed on Aug 14, 2026. by Ms Sanjeda Chowdhury Superintendent Pharmacist + Independent Prescriber Registered with GPhC (No. 2202465) Next review due on Aug 14, 2029.
Sanjeda

Last updated on Aug 19, 2026.

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Why is the 7.2mg dose different?

Dose Delivery rules Temperature rules Why?
Wegovy FlexTouch pen: 0.25mg, 0.5mg 1mg, 1.7mg and 2.4mg Can be transported below 30°C for up to 48 hours. Unopened pens should be refrigerated at 2–8°C at home until they expire. Opened pens can be stored below 30°C for up to six weeks. MHRA rules allow the pen to be transported without any refrigeration. This is because the chemical structure remains intact if transported below 30° for 48 hours.
Single dose pen 7.2mg Must be transported in a temperature-controlled system. Unopened pens should be refrigerated at 2–8°C at home until they expire. Opened pens can be stored below 30°C for up to six weeks. The 7.2mg dose has a different pen design to fit the larger volume of medicine, so it has different storage requirements.

Tips for storing Wegovy

Fridge placement

  • Store Wegovy with the box, not as single pens.
  • Aim to keep your fridge temperature between 2°C and 8°C.
  • It’s best to store it on the middle shelf, where the temperature is most stable.
  • Avoid keeping it on the lower shelf, towards the back or in the drawer, as this could freeze the pen and damage the medicine.
  • Don’t store it on the fridge door, as the constant opening and closing can cause the temperature to fluctuate, which could affect the medicine.
  • The medicine can be kept in the fridge until it expires.

Never freeze

Wegovy pens should never be frozen. Freezing the pens alters the medicine’s chemical structure, making it inactive. If you accidentally freeze the pen, make sure to dispose of it safely. Don’t inject it, as this could potentially be harmful.

Keep away from heat

Wegovy pens should be stored in conditions below 30°C, as high temperatures can damage the medicine. High heat can alter the protein structure of the medicine, making it ineffective.

When storing at room temperature after opening, keep it in a cool, dark place and avoid direct light, as this can also damage the medicine. If your pen is stored above 30°C for a prolonged time, you should discard it.

During periods of hot weather, a pharmacy may choose to send Wegovy via cold-chain delivery to prevent the injection being stored at temperatures above 30°C.

Final thoughts: A note from our expert

Sanjeda Chowdhury, Superintendent Pharmacist at Treated:

‘When it was first manufactured and approved, semaglutide (the active ingredient in Wegovy) was transported and stored at cool temperatures. Now there’s a lot of supporting evidence showing that it remains effective when transported and stored without being refrigerated. This makes it much more convenient for online pharmacies and users.’

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