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Given that there are so many treatments to choose from, pinning down the right HRT for you can be a bit daunting. We’re here to make it a whole lot simpler.

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Answer a few questions about your health so we can get to know you better.
Free 24h delivery
Your treatment delivered in secure packaging, the very next day.
We’ll check in with you regularly to see how your treatment is going.
This page was medically reviewed by Dr Daniel Atkinson, GP Clinical Lead on August 02, 2022. Next review due on August 01, 2024.
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    Menopause (HRT): Here's what we've got.
    Blister strip of Premique tablets



    Combined continuous HRT pills, at a lower dose. Good if you're sensitive to hormones.

    • Starting from £27.00
    Individual Estraderm patch in packaging

    Estraderm MX


    Oestrogen-only HRT patch. Change twice a week and reduce menopause symptoms up to 75%.

    • Starting from £28.00
    Sachet of Sandrena gel



    Oestrogen-only gel that's stronger than oestrogel. Used alongside a progestin for combined HRT.

    • Starting from £29.00
    Individual Estradot patch in packaging



    Simple treatment for menopause symptoms. Estradot is a HRT patch you change just twice a week.

    • Starting from £28.00
    Blister of Trisequens tablets



    Combined treatment for menopause relief. Sequential pills for women who no longer have periods.

    • Starting from £32.00
    Individual Evorel Conti patch

    Evorel Conti


    Combined continuous HRT patch. Used it's been more than 12 months since your last period.

    • Starting from £35.00
    Blister strip of Zumenon tablets



    Oestrogen-only pill for menopause treatment. Same hormones as Elleste Solo, different brand.

    • Starting from £31.00
    Blister strip of Femoston tablets



    Comes as a continuous or sequential tablet, depending on whether you're still having periods.

    • Starting from £40.00
    Sachet containing individual Evorel Sequi patch

    Evorel Sequi


    Sequential dose patch. Use to manage menopause symptoms if you still have periods.

    • Starting from £35.00
    Round pink tablet dispenser with tablets labelled with days of the week



    Like Elleste Duet, but continuous. Good for menopause symptoms if you no longer have periods. 

    • Starting from £33.00
    Blister pack of Elleste Duet tablets

    Elleste Duet


    Combined sequential HRT tablets. For treating menopause symptoms if you still have periods. 

    • Starting from £30.00
    Blister strip of Indivina tablets



    Continuous combined HRT pill. Made for menopause symptoms if you haven't had a period in 1 year.

    • Starting from £46.00
    Blister strip of Elleste Solo tablets

    Elleste Solo


    Oestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.

    • Starting from £26.00
    Kliovance Blister Pack



    Like Kliofem, but half the dose. HRT pill that’s good if you're sensitive to hormones.

    • Starting from £35.00
    Blister strip of Livial tablets



    A daily tablet for post-menopausal symptoms. It’s hormone-free, but works just like female hormones.

    • Starting from £31.00
    Novofem Blister Pack



    Like Elleste Duet with fewer hormones. Effective HRT that’s good if you're sensitive to oestrogen.

    • Starting from £33.00
    Dash of Oestrogel gel



    HRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.

    • Starting from £27.00

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    Further reading

    All the info related to menopause (hrt) you could ever need.
    Take a look at our health guides.

    Menopause, HRT and weight: what’s going on?

    Menopause, HRT and weight: what’s going on?

    One concern some women may have during menopause is about weight gain and many assume that HRT contributes to this. In fact, it’s quite normal for women to put on weight as they go through menopause, but many factors can play a part.

    Read more  

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    Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.

    What is HRT?

    HRT, or hormone replacement therapy, is treatment that women take to help relieve menopausal symptoms like night sweats, hot flushes, vaginal dryness, poor sleep, brain fog, mood swings and lower sex drive.

    How long you take it for can vary; many women take it for a year or two but some can take it for much longer than this. It’s a very individual thing. Certain types of HRT will also suit you more than others. Our clinician can talk you through the different options, and help you to decide which one is right for you.

    How does HRT work?

    As you enter the menopause, the levels of oestrogen that your body produces start to decrease, due to a shift in the balance of your sex hormones. This can cause symptoms such as hot flushes, night sweats and changes to your mood. HRT contains synthetic oestrogen, which makes up for the natural oestrogen that’s lost, and helps to tackle menopausal symptoms.

    Combined forms of HRT also contain a second hormone: a synthetic form of progesterone. Without anything to keep it in check, oestrogen may increase your risk of getting endometrial cancer, as it can cause the womb lining to thicken more than it should. The progesterone in combined HRT offers protection from this, keeping the oestrogen in line and reducing the risk of womb cancer developing. It’s more convenient to take combined HRT as a pill or patch which contains both progesterone and oestrogen, but sometimes it’s better to take these separately.

    If you’ve had a total hysterectomy though, because your womb has been removed, you’ll usually be prescribed oestrogen only HRT.

    The menopause can also cause your bones to become more fragile and more prone to breaking. HRT can provide some protection against osteoporosis by helping the bones to stay strong. HRT isn’t a primary treatment for osteoporosis though, so if you’re looking to use it for this purpose, just let our clinician know and they can chat to you about it.

    HRT benefits

    The major benefit of HRT is that it can help to ease many symptoms of the menopause (by as much as 75%, so quite a lot then).

    The oestrogen and progesterone in combined HRT make a good team. The oestrogen helps to manage symptoms of the menopause whilst the progesterone helps to keep it in check and reduces your cancer risk.

    And there’s the protection it can provide from osteoporosis too, when the bones in the body are more at risk of breaking or becoming brittle after the menopause.

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    Medically reviewed by
    Dr Daniel Atkinson
    GP Clinical Lead
    on August 02, 2022.
    Meet Daniel  
    This page was medically reviewed by Dr Daniel Atkinson, GP Clinical Lead on August 02, 2022. Next review due on August 01, 2024.

    How we source info.

    When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

    What forms of HRT are there?

    There are a number of different types of HRT available, and we can talk you through your options.


    Tablets are one of the most widely used types of HRT. There are tablet options for both combined HRT and oestrogen only HRT, and you normally take them once every day. They do carry a slightly increased risk of blood clots and breast cancer than other forms of HRT treatment, but it is only a small increase (nine more women develop a blood clot for every 10,000 women each year). Because of this increased breast cancer risk, make sure you attend your breast cancer screening (mammogram) appointments.

    Skin patches

    If you find having to remember to take a tablet every day a bit inconvenient, skin patches may be a more low maintenance treatment for you and they’re safer for your heart than tablets. You stick HRT patches to your skin, and change them twice a week. They’re available as a combined HRT treatment or as an oestrogen only medication. Skin patches can be a strong option if you’re prone to side effects such as indigestion, and they don’t increase your risk at all of developing a blood clot, unlike tablets.

    Oestrogen gel

    More and more women are starting to use oestrogen gel for menopausal symptoms, and it’s probably because it’s really easy to use. You just need to rub it onto your skin once a day. It doesn’t increase your blood clot risk either, but if you still have your womb, you’ll need to use an additional progesterone, to limit your chances of getting womb cancer.


    They’re not particularly common, but you can also get a HRT implant, which releases oestrogen slowly into the body and doesn’t need to be replaced for several months at a time. You’ll need to take a separate progesterone though if you’ve still got your womb.

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    So what is the best HRT for me?

    It depends on a number of factors, like what stage of the menopause you’re at, how sensitive you are to certain levels of hormones, and whether you prefer to take tablets or use patches, for example.

    Whether or not you’ve had a total hysterectomy is also a factor, and if you have certain health conditions, that can play a big part too.

    Here are your options. Our clinician can talk you through them, and recommend safe and suitable HRT treatments just for you.

    Combined sequential HRT

    If you’re getting menopausal symptoms and still having your period, combined sequential (or cyclical) HRT treatments are usually the recommended options. Combined HRT products like Elleste Duet and Evorel Sequi patches are known as ‘combined’ treatments because they contain two hormones: a progesterone and an oestrogen.

    With sequential HRT, you start your cycle with oestrogen only tablets (or patches) and then take a combination of oestrogen and progesterone tablets (or patches) part way through your cycle.

    You’ll see a regular bleed once per month with sequential HRT.

    Continuous combined HRT

    If you haven’t had a period for one year, you’re usually considered to be postmenopausal, and continuous combined HRT products like Indivina and Evorel Conti tend to be the suggested route. With continuous combined HRT treatments, you take a combination of oestrogen and progesterone every day, without a break (hence ‘continuous’). So they’re a little different to sequential HRT products. You won’t see any bleeding with continuous HRT, but if it’s less than a year since your last natural period, starting continuous HRT might lead to some unpredictable bleeding. So it’s best to start with sequential HRT.

    Oestrogen only HRT

    Oestrogen only treatments such as Elleste Solo and Estradot patches are normally recommended for women who have had their womb removed during a hysterectomy. They can also be used by women who still have their womb, but a separate progesterone is required (either as a tablet, a vaginal capsule, or a gel for the skin). Like continuous combined HRT, you typically take oestrogen every day, without a break.

    Side effects of HRT may also vary from one woman to the next, so some HRT medications won’t be safe (or suitable) for some women. If you’re more sensitive to oestrogen, you may be better suited to lower-dose HRT products. And if you have a particular health condition, this can mean that certain HRT products won’t be safe for you to use either.

    Our clinician can identify which treatments are appropriate for you and which aren’t, and make recommendations based on your medical background.

    What HRT alternatives are there?


    There’s a prescription HRT medicine called Tibolone (branded as Livial) that’s used to relieve menopausal symptoms and as a preventative treatment for osteoporosis. Tibolone is the active ingredient, so it’s a bit different to other forms of HRT, which contain oestrogen and progesterone (or just oestrogen).

    It can help to ease symptoms like hot flushes, reduced sex drive and low mood, but research has suggested that Tibolone may be less effective than combined HRT. It’s also only a suitable option for women who are postmenopausal (so women who had their last period over a year ago).

    Tibolone can produce side effects, including breast pain, vaginal discharge, pain in the pelvis, itching and abdominal pain.

    The slightly increased risks of breast cancer and stroke that HRT carry are similar with Tibolone.


    Clonidine is another prescription treatment that’s sometimes used to help tackle symptoms like flushing and night sweats. It’s a tablet that you take two or three times a day, and it has no effect on hormone levels, so there’s no increased risk of breast cancer for example. Studies suggest that it only has a small impact on easing flushing and night sweats though, and it can have unpleasant side effects too.

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    FAQ: HRT

    Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

    What’s the difference between Elleste Solo and Elleste Duet?

    Although both come under the label HRT, they don’t treat the same thing, or at least the same part of the menopausal cycle.

    Elleste Solo is prescribed to treat the post menopause, when your period has stopped. It contains one active ingredient, estradiol (oestrogen). Elleste Duet contains a progesterone called norethisterone, as well as an oestrogen, making it a combined HRT.

    So why the two versions? Oestrogen prescribed by itself for those over the age of 35 can greatly heighten the risk of cancer and endometrial hyperplasia. The synthetic progesterone in Elleste Duet decreases that risk while providing the same benefits.

    This is not an issue if you have had a hysterectomy and is why Elleste Solo can only be prescribed for postmenopausal women who have had one.

    Should I use Elleste Solo patches or tablets?

    There’s no difference in effectiveness between Elleste Solo tablets and patches. It really depends on you. Some people may get some skin irritation from the patches, while others may have difficulties swallowing tablets.

    Whatever the reason you make your choice, you can rest assured that you’re getting the most from the treatment when it’s taken as instructed.

    What do I need to know before using Elleste Solo?

    If you still have regular periods, HRT needs to be taken on the first day of bleeding, otherwise you can start to take it straight away, which is only relevant if you’re taking a separate progesterone treatment alongside Elleste.

    If you’re changing from another type of HRT, you should take your first Elleste Solo the day after you finish the previous treatment unless your clinician has instructed you otherwise.

    What are the Elleste Solo dosages?

    Elleste Solo has two dosages for each form. Elleste Solo 1mg tablets and the stronger 2mg dosage are mirrored by Elleste Solo MX 40 and MX 80 for the patch. It’s likely you will be prescribed the lower dosage to begin with and it will be increased only if it proves to be ineffective for you.

    If you’re uncertain about whether your dose is right for you, or if it isn’t effective or causing side effects, let our clinician know via your Treated account. They can discuss adjusting your dose with you if appropriate.

    Is Zumenon the same as Elleste Solo?

    In short, yes. Elleste Solo and Zumenon contain the same active ingredient, estradiol hemihydrate, and in the same dosages, 1mg and 2mg. The only difference between the two is packaging, name and price.

    Elleste Solo is usually a little cheaper, but it’s always recommended to compare pricing on products that contain the same ingredients in the same dosages.

    Why should I Buy Elleste Solo online with Treated?

    The convenience of taking an online consultation with our clinicians is that you don’t need to make appointments or even leave your house. We can make tailored treatment recommendations for you, based on your medical background. You then choose your HRT treatment and your delivery schedule, and we’ll do the rest. Change, pause or cancel your subscription at any point.

    Once you have your treatment, we want to be sure that it’s working well for you too. That’s why we also provide an aftercare service where you can get in touch with us about any issues you’re having with your medication.

    Is Kliofem the same as Elleste Duet?

    While they do contain the same hormones, Kliofem is a continuous combined HRT tablet, whereas Elleste Duet is a combined sequential HRT tablet. So you take the treatments in different ways.

    Kliofem is also an HRT product that’s recommended for postmenopausal women who haven’t had a period for at least one year, whereas Elleste Duet is a treatment for menopausal women who are still experiencing their period.

    Can I delay my period on Elleste Duet?

    It’s not normally advisable, and it’s very important that you discuss it with our clinician in the first instance. In some cases, women delay their periods whilst taking Elleste Duet by taking additional tablets as opposed to maintaining the 28-day cycle.

    Taking too many tablets with oestrogen in them can be dangerous as a rise in oestrogen levels in the body will make the uterine lining thicken excessively. This increases your risk of developing womb cancer. So you should always talk about delaying your period with our clinician first.

    Novofem and Elleste Duet: are they the same?

    Both Novofem and Elleste Duet contain estradiol and norethisterone acetate and they’re both combined sequential HRT treatments. The pill regime is the same too. It’s just the colour of the pills that are different, along with the manufacturer and the packaging (like Kliofem, Novofem is made by Novo Nordisk, rather than Mylan).

    Novofem is also only available in one dose: 1mg estradiol and 1mg norethisterone, rather than as a low dose and medium dose tablet.

    Why should I buy Elleste Duet online with Treated?

    With a Treated subscription, you can buy Elleste Duet online without having to make an appointment with a clinician. Once you’ve told us about your health, we’ll recommend treatment options that are safe and suitable for you. You can then choose your medication, and how often you’d like to receive it too.

    And once you’ve bought your treatment, we’ll be in touch regularly to see how you’re getting on with your medication. You can change, pause or cancel your subscription anytime.

    What size are the Evorel Sequi patches?

    HRT patches are designed to be discreet. Measuring just 4cm accross, they are easily hidden under clothing, usually on the bottom half of the body (but more on that later).

    They essentially look like small plasters and are just as thin, meaning they are unlikely to show through your clothing. As long as they’re placed on a hairless part of the bottom half of the body, and not where you might wear elastic, you can put them anywhere you feel is most discreet.

    What problems can the menopause cause?

    The menopause describes hormonal changes in the body that lead to the end of your period and your ability to become pregnant naturally. This usually happens between your mid 40s and mid 50s, but can occur earlier in some women.

    The menopause can have a major impact on your life, both physically and psychologically, so having the option of a treatment like HRT can be life changing.

    Symptoms of the menopause include: hot flushes, mood changes, an inability to concentrate, vaginal dryness, insomnia, night sweats and a significant drop in sexual desire. These symptoms can build slowly, in some cases lasting several years before your period stops completely.

    Evorel Sequi patches can also be used to prevent osteoporosis, a bone condition that often occurs in menopause and leads to brittle or deformed bones.

    How do I change the Evorel Sequi patch?

    Removing the patch is easy. Just peel it off and fold it over so the sticky side attaches to itself. This prevents any remaining hormones from being picked up by children or pets.

    Always throw the patch away, and don’t flush it down the toilet. After the patch has been removed it might leave some glue on your skin. This will fall off over time, or you can remove it with soap and water or baby oil.

    Can I buy Evorel Sequi patches over the counter?

    You’ll need a prescription to get Evorel HRT patches. HRT treatments can have side effects, and certain products may not be suitable for you if you have an existing health condition, or if you’re currently taking other medications, for example.

    So you’ll need to have a consultation with a clinician first to assess if Evorel Sequi is safe for you to use, during which it’s important to tell them about your medical history and any treatments you’re currently using.

    Why should I buy Everol Sequi patches online from Treated?

    We’ll not only help you to find the right HRT treatment for you, we’ll check in with you regularly afterwards, to see how you’re getting on with it. If it’s not working for you the way it should, or if you’d like to switch to something else, we can see to that.

    Our clinicians are on hand to answer any questions you might have, or to talk you through any concerns. Send them a message using your Treated account, and they’ll get right back to you. You can change, pause or cancel your subscription at any point.

    Is Zumenon similar to any other treatments?

    Zumenon and Elleste Solo are the exact same medication produced and marketed by different companies. Other oestrogen HRT treatments are delivered through transdermal patches and other routes. People who take Zumenon may prefer the ease of taking a pill, while other people prefer patches and other methods that don’t require daily adherence.

    How is Zumenon different from other HRTs?

    Zumenon is a continuous HRT pill that only contains oestrogen. It’s a safe treatment for women who have had a hysterectomy. If you haven’t had a hysterectomy, you may need a treatment that combines oestrogen and progesterone.

    Which dose of Zumenon should I use?

    It’s safest to start any HRT treatment on the lowest dose available to avoid side effects. With Zumenon, our clinician will most likely start you on 1 mg and increase your dose to 2 mg if you need more relief. Talk to our clinician so they know if you need an adjustment to your dose.

    Do I need a prescription for Zumenon?

    All hormone replacement therapy drugs require monitoring by our clinician As a result, Zumenon is not available over the counter. Our clinician will need to review your health background and decide if Zumenon is safe for you to use before prescribing you with it.

    Why should I buy Zumenon online with Treated?

    We’re keeping HRT simple. Tell us about your health, and we’ll advise you on safe and suitable treatments just for you. Choose your medication, and how frequently you’d like to receive it from our pharmacy. And the amount of treatment each time too.
    We’ll check in with you on a regular basis to see how you’re getting on with your medication. You can change, pause or cancel your subscription at any point.
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