What is Candesartan?
Candesartan is used to treat high blood pressure (hypertension). It belongs to a group of medications called angiotensin II receptor blockers (ARBs). These help your blood vessels relax and widen which lowers your blood pressure. This makes it easier for your heart to pump blood around your body. Candesartan can also be used for heart failure where your heart muscle doesn’t function well.
It’s taken orally as a tablet and is available in five doses, which you take once daily.
If left untreated, high blood pressure can lead to a higher risk of health problems such as heart attacks, heart disease, strokes, and kidney disease. Around 32% of UK adults are thought to have high blood pressure, and because it doesn’t cause symptoms you might not always know when you have it.[1]
You record blood pressure by looking at two numbers: systolic pressure and diastolic pressure. Systolic pressure is the force your heart uses to pump blood around your body. Diastolic pressure is the pressure level in your arteries between heartbeats. A reading of over 140/90mmHg is considered to be high blood pressure.
How does Candesartan work?
Candesartan works by blocking the receptors a hormone called angiotensin II binds to. Angiotensin II constricts blood vessels which can raise blood pressure. Candesartan will relax and widen your blood vessels, by blocking the action of the hormone. This lowers your blood pressure and makes it easier for your heart to pump blood around your body, and for blood and oxygen to reach your heart as well.
Who is Candesartan for?
Candesartan is for people who have already tried taking other hypertension treatments, such as ACE inhibitors (like ramipril and lisinopril), that didn’t improve their symptoms.
If you have diabetes, a condition that affects your liver or kidney, or if you’ve had an allergic reaction to candesartan or any other types of ARB, you won’t be prescribed the tablets. In this case, your clinician will help you find a more suitable treatment.[2]
What doses are available for Candesartan?
Candesartan is available in five different doses: 2, 4, 8, 16, and 32mg of candesartan cilexetil. You’ll be given the lowest dose to start with and your prescriber may then increase the dose afterwards.
For high blood pressure, you may be prescribed 8mg to 32mg once a day. For heart failure, it’s 4mg to 32mg once a day.
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