Blissel Vaginal Gel is a treatment for vaginal dryness that you insert into the vagina. It contains estriol, a type of oestrogen and steroid that occurs naturally in the body. It’s applied straight to your vagina, so it shouldn’t affect other aspects of your health.
Using Blissel Vaginal Gel helps your vagina make its natural lubrication again. This protects you from vaginal infections, atrophy and painful sex. Blissel is the only gel form of estriol currently available. You might find it easier to use than tablets, pessaries or creams.
How does Blissel Vaginal Gel work?
After the menopause, your body stops producing as much of the female sex hormones as it used to. This can change how your vagina works. It can lead to the walls of your vagina becoming thinner, dryer and more easily irritated.
The estriol in Blissel Vaginal Gel works directly on the vagina, increasing the oestrogen levels in the area. It makes the tissues of your vagina work normally again and restores the microflora and pH balance. This keeps your vagina healthy and combats dryness.
What doses of Blissel Vaginal Gel are there?
Your dose will depend on your symptoms and general health. A clinician will help you figure out the right dose for you. You’ll often start using one 1g tube of Blissel Vaginal Gel a day, which contains 10mcg of estriol. After three weeks, your symptoms will usually have improved and you can lower the dose to one 1g tube twice a week.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Blissel Vaginal GelEstradiol (Estriol)
How to use Blissel Vaginal Gel
Your pack of Blissel Vaginal Gel should come with the required amount of disposable cannulas, one reusable white plunger and one tube of the gel. Only use Blissel Vaginal Gel as your clinician tells you to.
If you’re using it for the first time, pierce the tube of gel with the spike on the outside of the cap. Don’t use it if the seal’s already been broken.
Take out one of the cannulas and a white plunger.
Insert the white plunger all the way into the cannula to make the applicator. Screw the cannula onto the neck of the tube of gel.
Squeeze the tube of gel until the applicator is full up to the mark. You’ll know when this is, as the plunger stops moving at the mark.
Unscrew the cannula from the neck of the tube and put the cap back onto the tube.
Lie down and insert the applicator deep into your vagina. Slowly push the plunger until it is all the way down.
Remove the applicator from your vagina and take the plunger out of the cannula.
Throw the used cannula away.
Wash the plunger well with warm water so it can be reused.
How long does it take Blissel Vaginal Gel to work?
Blissel Vaginal Gel is absorbed rapidly. Peak plasma concentrations happen at around two hours after using. But it can take some time to see its full effects, as it needs time to change how the tissues of your vagina are working. Most people will see an improvement in the lubrication of their vagina within a few weeks, so they can switch to the maintenance dose. If you have been using Blissel Vaginal Gel for three weeks and you don’t feel it’s working, go back to your clinician or message us if you’re using our service.
What should I do if I make a mistake when using Blissel Vaginal Gel?
If you use too much Blissel Vaginal Gel or even swallow it, there’s probably no need to worry. The dose of estriol in Blissel is very low so it’s unlikely to cause problems. There’s a chance you might feel some nausea or experience extra vaginal bleeding. If any of these symptoms worry you, contact your clinician.
If you forget to take Blissel, just apply it when you remember. If it’s less than 12 hours until your next dose, you can skip it and carry on with your treatment as normal. Don’t use more Blissel Vaginal Gel than you're prescribed to make up for missing a dose. If you keep forgetting your dose, try setting an alarm or using a reminder app to help you remember.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Blissel Vaginal GelEstradiol (Estriol)
Blissel Vaginal GelEstradiol (Estriol)
FAQ: Blissel Vaginal Gel
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
How is Blissel Vaginal Gel different from other treatments for vaginal dryness?
Answer:
Blissel Vaginal Gel is currently the only topical gel used for vaginal dryness. So if you don’t want to take tablets like Vagifem, creams like Ovestin or pessaries like Imvaggis, Blissel might be a good choice for you.
While other HRT treatments can also help with vaginal dryness, Blissel Vaginal Gel only works locally on the vagina. Not much is absorbed into the blood and becomes active there. So if you want to treat vaginal dryness without dealing with other possible side effects of HRT, talk to your clinician about Blissel.
Which dose of Blissel Vaginal Gel should I use?
Answer:
Your clinician will tell you exactly what dose of Blissel Vaginal Gel is right for you. Women usually start on a daily dose of one 1g tube, before moving onto a twice weekly dose when their vaginal dryness has improved. The dose you need might depend on your individual health. If you’re interested in Blissel Vaginal Gel, you can chat to our clinicians about your symptoms. We’ll recommend a dose that should work for you.
How effective is Blissel Vaginal Gel?
Answer:
Blissel Vaginal Gel has proven to be safe and effective at treating vaginal dryness. It’s also been shown to treat many of the uncomfortable related symptoms. A study of 167 women found that Blissel significantly improved vaginal dryness.
12 weeks of Blissel treatment also reduced the number of parabasal cells and lowered the pH of the vagina. A high number of parabasal cells and a high vaginal pH are both signs of the menopause that can lead to vaginal dryness, atrophy, infection and pain. So using Blissel doesn’t just help with dryness, it makes your vagina healthier overall.
Do I need a prescription for Blissel Vaginal Gel?
Answer:
You will need a prescription for Blissel Vaginal Gel. It’s made for women with vaginal dryness due to the menopause and other hormonal conditions. So a clinician will need to make sure it’s the right choice for you. As it contains a type of oestrogen, it’s also not a good choice for everyone based on other aspects of their health.
Why should I buy Blissel Vaginal Gel online with Treated?
Answer:
Vaginal dryness can be difficult to deal with, but we’re here to help. If you’re struggling with your symptoms, just talk to one of our clinicians. We’ll listen and recommend some treatments that might help you.
Order Blissel Vaginal Gel with us and we’ll deliver straight to your door in discreet packaging. You can also pick our subscription service, so your medication arrives on time every month. No need to remember to reorder. Ordering with us also gets you access to our expert clinical team, who are always on hand if you have any questions. We’ll also check in with you during treatment to make sure it’s working well for you.
Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
Cano, A., Estévez, J., Usandizaga, R., Gallo, J., Guinot, M., Delgado, J., Castellanos, E., Moral, E., Nieto, C., del Prado, J. and Ferrer, J., 2012.
The therapeutic effect of a new ultra low concentration estriol gel formulation (0.005% estriol vaginal gel) on symptoms and signs of postmenopausal vaginal atrophy. Menopause, 19(10), pp.1130-1139.
