Gels
Testosterone gels include Tostran, Testogel, and Testavan.
- Testosterone gels are one of the most commonly used forms of TRT.
- They're applied to the skin, where the testosterone is absorbed directly into the bloodstream to help raise testosterone levels.
- They're typically applied once a day, ideally at the same time each day.
- Gels are an easy and convenient treatment option, as you simply apply the gel and allow it to dry for around five minutes before getting dressed.
- Most gels begin reaching effective blood levels within around an hour of application and achieve steady testosterone levels after the first few days of regular use.
- But it may take several weeks before you notice an improvement in your symptoms.
- The main drawback is that the treatment relies on correct application. Applying too much or too little, spreading the gel unevenly, or not allowing it to dry properly can reduce its effectiveness.
Long-acting injections
Common brands include Nebido.
- Long-acting injections slowly release testosterone over several weeks.
- They're administered into a large muscle, such as the buttock, thigh, or upper arm, by a healthcare professional.
- Depending on the medication, injections are only needed every few weeks. For example, Nebido is typically given once every 10 to 14 weeks, meaning most people only need around four to five injections per year.
- This helps maintain stable testosterone levels without causing large fluctuations.
- One of the biggest advantages is convenience, as they're required much less frequently than gels or short-acting injections.
- The main disadvantage is that they usually need to be administered by a healthcare professional, so you'll need to book and attend an appointment for each injection.
Short-acting injections
Common brands include Sustanon 250 and Depo-Testosterone.
- Short-acting injections need to be administered more frequently than long-acting injections because the testosterone leaves the body more quickly.
- Depending on the medication, injections may be required every few days or every one to three weeks.
- They're administered into a muscle, such as the buttock, thigh, or upper arm.
- After the injection, testosterone is gradually released into the bloodstream to help increase testosterone levels and relieve symptoms of low testosterone.
- After receiving appropriate training, you may be able to self-administer the injections at home.
- The main disadvantage is the need for more frequent injections compared with long-acting options, which some people find less convenient.
