Combined relief and prevention for moderate to severe COPD.

Trimbow is a daily-use inhaler for symptoms of moderate to severe COPD. Its active ingredients relax the muscles in your airways and reduce inflammation in your lungs. This should ease your day-to-day symptoms, and help to prevent them in the future.
Tell us a little about your health in our online consultation, and we’ll show you the COPD treatments that suit you. When you order Trimbow online with Treated, we’ll check in to make sure everything is working as it should, and answer any questions you may have.
Trimbow is a combined prevention and relief inhaler used to treat symptoms of moderate to severe COPD. It’s a type of single inhaler triple therapy, as it contains three active ingredients in one inhaler.
Formoterol belongs to a group of medicines called long-acting beta agonists (LABA), and glycopyrronium is a long-acting muscarinic antagonist (LAMA). These are both types of long-acting bronchodilator, medicines that relax and widen your airways so you can breathe more easily. As they’re long-acting, you’ll feel their effects for about 12 hours.
Beclometasone, on the other hand, is a corticosteroid, which targets and reduces inflammation in your lungs. Together, these should relieve symptoms of COPD and work to prevent them.
Trimbow’s three active ingredients work in slightly different ways to tackle your COPD.
Formoterol and glycopyrronium are bronchodilators that relax the muscles in your airways, relieving symptoms of COPD. They can be prescribed individually – but if you’ve got moderate or severe COPD, and struggle to control it with a single treatment, taking both can help improve your symptoms. In clinical trials dual therapy has shown to improve lung function, ability to exercise, quality of life, and frequency of flare-ups – slowing down the progression of COPD.
Beclometasone, on the other hand, inhibits the actions of inflammatory cells in your lungs. This reduces irritation and swelling in your airways, and should help prevent your symptoms occurring in the future.
We currently offer two different types of Trimbow inhaler, but they both contain what amounts to the same dose of medicine. The Trimbow inhaler doses we offer are as follows:
Trimbow metered dose inhalers (MDI) have a delivered dose (the dose that leaves the mouthpiece) of 87 mcg beclometasone, 5 mcg formoterol, and 9 mcg glycopyrronium. They deliver the medication in a pressurised solution that’s released when you activate the inhaler.
Trimbow NEXThalers have a delivered dose of 88 mcg beclometasone, 5 mcg formoterol, and 9 mcg glycopyrronium. NEXThalers are dry powder inhalers (DPI), which contain the medication as a powder that you inhale.
For severe COPD, you can also get Trimbow inhalers containing 172 mcg/5 mcg/9 mcg of beclometasone, formoterol and glycopyrronium respectively. However, we don’t currently offer this dose of Trimbow.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
We offer two different kinds of Trimbow inhaler, and how you use it depends on which you have.
You should only use your Trimbow MDI inhaler as your clinician has instructed. The typical dose is two puffs in the morning, and two in the evening. If it’s the first time you’re using your inhaler, you should make sure it’s working properly.
To use your Trimbrow MDI inhaler:
If you see any ‘mist’ escaping from the top of the inhaler or sides of your mouth, start your puff again from step 2. This ensures that you’re getting enough medicine into your lungs to treat your symptoms.
Rinsing your mouth with water or brushing your teeth after using Trimbow helps prevent fungal infections in your mouth and throat.
Only use your Trimbow NEXThaler as instructed by your clinician. The usual dose is two puffs in the morning and two in the evening. Before using your inhaler for the first time, check that it’s working properly:
To use your Trimbow NEXThaler:
The different active ingredients in Trimbow will work to relieve your symptoms in the short term, and prevent them long-term.
Formoterol will typically take effect within one to three minutes, and glycopyrronium reaches peak levels at around five minutes after your dose. As they’re long acting bronchodilators, you should feel their effects on your airways for up to 12 hours after your dose. However, if you find yourself struggling to breathe, you’ll need to use a separate reliever inhaler. Trimbow won’t provide relief from COPD symptoms in the moment.
Beclometasone needs a little longer to take effect; it’ll take around three to seven days before you start noticing its benefits. You should find yourself short of breath and wheezing less often, as it works to suppress inflammation in your airways. If you’ve been taking beclometasone for over a week and haven’t noticed any improvement, get in touch with your clinician.
You should only use your Trimbow inhaler as your clinician instructs you to. If you’ve forgotten to take a dose of Trimbow, use it as soon as you remember. If your next dose is just around the corner, miss the dose you forgot to take, and take the next one at the correct time. Never take two doses to make up for a missed one.
If you take more Trimbow than you should, it’s unlikely to cause any immediate side effects – especially if it’s just the once. If you do experience any side effects after using too much Trimbow, like a headache or changes to your heart rate, speak with your doctor. If you use too much Trimbow over an extended period of time, you could suffer from adrenal suppression. This is where your adrenal glands don’t produce enough of certain hormones.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Bronchodilator that provides twenty-four-hour COPD relief. Combines an LABA with an anticholinergic.
Eases symptoms and stops COPD getting worse. Powder or capsule options.
Powder inhaler with three active ingredients to improve COPD.
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Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
Single Inhaler LABA/LAMA for COPD. Frontiers in Pharmacology. vol. 10, no. 390.
‘Inhaled Corticosteroids.’ Pharmaceuticals, vol. 3, no. 3.
Formoterol Easyhaler 12 micrograms per dose inhalation powder.
Seebri Breezhaler 44 micrograms inhalation powder, hard capsules.
‘Adrenal suppression: A practical guide to the screening and management of this under-recognised complication of inhaled corticosteroid therapy.’ Allergy, Asthma & Clinical Immunology, vol. 7, no. 13.
Comparing the Efficacy and Safety Profile of Triple Fixed-Dose Combinations in COPD: A Meta-Analysis and IBiS Score. Journal of Clinical Medicine. 11, 4491.
Trimbow (beclometasone / formoterol / glycopyrronium bromide).
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