Relieves nausea within an hour.

Buccastem is a tablet used for nausea and vomiting associated with migraines. It’s a type of tablet that you let dissolve between your upper lip and gum (called a buccal tablet).
Let us know about your health in our simple consultation, and order Buccastem M online for fast treatment delivery and tailored support.
Buccastem M is an anti-sickness treatment. Containing the active ingredient prochlorperazine maleate, it’s effective at treating nausea and vomiting, which are both symptoms commonly associated with migraines.
Prochlorperazine belongs to a class of drugs known as phenothiazines, which have multiple uses, including for schizophrenia, anxiety (although less preferred) and vertigo. It can be taken orally, rectally (by suppository), or administered into a muscle (by intramuscular injection). For treating nausea and vomiting, it’s taken orally as a buccal tablet.
Prochlorperazine, a phenothiazine medicine, blocks D2 dopamine receptors in the brain, preventing the transmission of messages that cause nausea and vomiting. It can also block histaminergic, cholinergic, and noradrenergic receptors, making it useful for treating allergy symptoms like hives and sneezing.
Buccastem is only available as a 3 mg dose of prochlorperazine maleate to be taken twice a day, where you’ll either take one or two tablets as recommended by your prescriber.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
You’ll take Buccastem twice a day with either one or two tablets for two days. It’s best to take it after you’ve eaten. Make sure you don’t drink alcohol while on this treatment, as it can cause side effects like drowsiness or an irregular heartbeat (palpitations).
To take Buccastem:
When the tablet gets wet, it turns into a gel which makes it easier to dissolve and be absorbed into your body. When you take it this way, it can start to work within 30 to 60 minutes, and the effects can last for 6 hours. When it’s administered by injection, it can work within five to ten minutes and lasts for three to four hours.
If you accidentally take too much Buccastem, seek urgent medical attention immediately. Bring any leftover pills or the empty packet with you. If you miss a dose, don’t take a double to make up for it. Just continue taking the medicine as instructed by your clinician. If you accidentally swallow it, don’t worry too much about it — it’ll just take longer to work.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Prochlorperazine. [Updated 2023 Mar 24]. In: StatPearls. Treasure Island (FL): StatPearls Publishing.
Prochlorperazine: medicine to help stop you feeling or being sick (nausea or vomiting). nhs.uk.
Orally disintegrating tablets, fast-dissolving, buccal and sublingual formulations. Pharmaceutical Development and Technology, 23(5), 431–431.
Great experience 👍
Great experience 👍
Excellent
Provided an anti-sickness that I have heard from the doctor before, although its near impossible to get an appointment so fast delivery and didn’t mind paying for it very very happy
Registered with GMC (No. 4624794)
Meet DanielRegistered with GPhC (No. 2202465)
Meet SanjedaRegistered with GPhC (No. 2070724)
Meet CraigDelivery, consultation, treatment. It’s all included in the price.
Quantity | Starting from |
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8 Tablets | £35.95 |
16 Tablets | £50.95 Save £20.95 |
24 Tablets | £65.95 Save £41.90 |
Quantity | Starting from |
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28 Tablets | £26.95 |
Quantity | Starting from |
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28 Tablets | £26.95 |
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Nausea: Here are some other options.
Tablet available in three different strengths that works in the brain to reduce nausea.
Tablet available in three different strengths that works in the brain to reduce nausea.
Fast-acting tablet for nausea and motion sickness. Can ease symptoms within 20 minutes.
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