Effective cream to treat vaginal dryness.
Gynest is a hormonal cream for vaginal dryness containing estriol (a weaker form of oestrogen). Because of this, the risk of side effects is lower.
To order Gynest, simply answer a few questions about your health. We’ll deliver it the next day, and stay in touch throughout your treatment journey.
Gynest contains estriol, a synthetic hormone that belongs to a group of medicines called hormone replacement therapy. It treats vaginal dryness, a condition that affects both premenopausal and postmenopausal women. The symptoms include discomfort or pain during sex, increased frequency of urinary tract infections, and itching or soreness around your vagina. These symptoms can often be helped by using vaginal moisturisers, lube during sex and unperfumed products to prevent irritation, but if hormonal changes are the cause of vaginal dryness, then HRT might be prescribed.
Estriol (the active ingredient in Gynest) is a synthetic version of the naturally occurring female hormone, oestrogen. It's weaker than oestrogen and shorter-acting.
Vaginal dryness often occurs because of low oestrogen production, which causes your vaginal epithelium (inner lining) to thin. This can then lead to symptoms like pain during sex. When estriol is applied topically, it treats these symptoms by stimulating the proliferation (growth of cells) in your vaginal epithelium. It also restores and maintains the pH of your vagina, reducing the risk of urinary tract infections.
Gynest is available as a 1mg/g cream. This means that every gram contains 0.1% of the active ingredient, estriol. It comes in a tube along with an applicator you insert into your vagina. Each evening, use one application of Gynest cream until your symptoms improve. After this, use it twice a week.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Gynest cream comes in a tube, along with a long applicator which you insert into your vagina. The tube can be screwed onto the plastic applicator, helping you put the right amount of cream in your vagina. Gynest is used daily until your symptoms improve. Your clinician will tell you more about which dose you should use.
To use the cream:
After application:
After each use, wash the applicator thoroughly.
If you break your applicator, you can typically get a new one from your local pharmacy.
Gynest takes a couple of weeks to relieve the symptoms of vaginal dryness. During the first couple of weeks, use the cream daily. After your symptoms improve, use the cream twice a week to prevent the symptoms returning.
If you forget a dose of estriol cream, use it as soon as you remember. But if it’s the next day, don't use it. Estriol should only be used once a day.
If you accidentally use more cream than you should, wash it out immediately. Using too much can cause side effects such as breast tenderness, nausea and spotting. If you get any of these symptoms, contact your clinician.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Vaginal dryness: Individualised patient profiles, risks and mitigating measures. The EPMA Journal, 10(1), 73-79.
Treatment of vaginal atrophy with estriol and lactobacilli combination: a clinical review, Climacteric, 21:2, 140-147.
Hormone Replacement Therapy. [Updated 2023 Feb 20]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing.
ReplensTM Vaginal Moisturiser - Resolve Dryness Symptoms. Replens.
Estriol 1mg/g cream - Summary of Product Characteristics (SmPC) - (emc).
Treating vulvovaginal atrophy/genitourinary syndrome of menopause: How important is vaginal lubricant and moisturiser composition? Climacteric, 19(2), 151-161.
Registered with GMC (No. 4624794)
Meet DanielRegistered with GPhC (No. 2202465)
Meet SanjedaRegistered with GPhC (No. 2070724)
Meet CraigDelivery, consultation, treatment. It’s all included in the price.
Quantity | Starting from |
---|---|
30 g | £56.95 |
We know health, but you know you.
Our experts tell you what’s safe, but you decide what’s best.
Answer a few questions and tell us about yourself. Get tailored advice from our clinicians so you can choose better.
Choose your treatment and how often you have it delivered.
We know things change. It’s the nature of life. We’ll check in regularly to make sure your treatment is still right for you.
Pause. Change. Skip. Start again. Any time you like.
Always arrives on time and I’m kept informed of progress.
I have had it previously from my G.P so It worked as expected, extremely well. My problem is an accessing my G.P practice, they put ED well down their list of priorities. I found your service excellent, quick and efficient. I fully intend to continue using it
Shipping is speedy and the product is amazing.
Fast, slick service. Very easy to amend subscription when required.
All good.
Great service
Really helped me
Trusted service and great service - next day delivery and I can rely on them to send regularly.
Ordering was straight forward, tablets delivered promptly and well packaged, and instructions were clear, thanks.
100% recomended.Great service
Excellent service
Excellent delivery. Can’t fault.
Quick and efficient service, delivered discreetly the next day. Thank you.
Effective
Great service, no wait time
Great
Quick assessing for medicine suitability. Quick delivery and good communication throughout.
Straightforward and quick service!
Good however communication could sometimes be better
Easy and good procedure to get treatment
Excellent product
Excellent service!!! Ordered what I needed sent a picture of my prescription and the parcel arrived the next day!!! Will definitely order again and have recommended to others!!!
Fast shipping
Very quick service all round
So quick and simple. Recommend
Great
Very convenient hassle free service.
Easy to use good communication and fast shipping
Great service
Efficient no issues re delivery
Fabulous service
Brilliant service. Not a bad word to say!
It was fast, professional and it's the right med for what I selected in there.
This review requires content. Oh well..
Great service, quite effortless.
Top notch
Brill service
N/a
Excellent service quick and easy to use
Fast and exact order
Superb service and quick delivery 10/10
Excellent service
Thank you for fast delivery
Shipping is extremely quick and satisfiying
Good stuff
Good service
Great fast delivery
We're making healthcare more about you. Sign up to our newsletter for personalised health articles that make a difference.
Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
We couldn't find what you're looking for.
Here's everything we treat. Or, if you're looking for something we don't have yet, you can suggest something.
If there’s a particular treatment or condition you’re looking for, tell us and we’ll look into it for you.
Submit your question here, or tell us if you’ve found an issue on our site.
We’ll get back to you very soon. We aim to respond to all queries in one working day.
You’re signed up to our newsletter. Keep an eye on your inbox for our latest update.
By clicking 'Subscribe now' you're agreeing to our Privacy Policy.
We’ve sent you an email asking you to confirm your email address.