Treats verrucas within two weeks.
NitroFreeze is a cryotherapy treatment for verrucas and warts. When applied to a verruca, it freezes it, making it fall off within two weeks.
To order NitroFreeze, simply answer a few questions online and choose the treatment you want. Then get it delivered straight to your door the next working day.
NitroFreeze is a cryotherapy medication to remove warts and verrucas. Cryotherapy is the method of using liquid nitrogen to deep freeze a wart or verruca, which makes it fall off. It’s a popular and effective medication to remove warts, with few side effects.
Verrucas are small bumps that form on the bottom of your foot. They’re caused by a virus and can be painful when walking or standing. Although they usually go away on their own, it can take several months or even years. Removing it with cyprotherapy can speed this up to just a couple of days.
NitroFreeze contains the active ingredient nitrous oxide. It's an extremely cold gas -89°C, making it suitable for cryotherapy.
When applied to a verruca, the cold temperature damages the blood vessels and tissues within that area, leading to cellular death. As the cells die, the immune system removes the damaged tissue, causing the verruca to eventually fall off within a couple of days.
NitroFreeze can be used on warts and verrucas. Warts are usually rough, skin-coloured bumps found on your hands and feet. Whereas verrucas are largely the same, except they’re found on the bottoms (soles) of your feet. If you're not certain that your bump is a wart or verruca, don't use NitroFreeze. Instead, ask a clinician to help you diagnose it.
Using NitroFreeze on normal skin can cause serious frostbite and permanent scarring. Additionally, don't use it on thin skin, such as your armpits, lips, breasts and genitals. For more information on where it can and can’t be used, check the patient information leaflet.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
It's important to read the instructions clearly and follow them accurately to avoid getting frostbite or causing damage to your skin.
Step 1 - Preparing the pen (First use only):
With the cap on, twist the white section of the pen one full turn until you hear a click.
Step 2 - Activation of the pen:
For verrucas, soak your foot in warm water for 5 minutes, then file your verruca down with a pumice stone or file and dry it thoroughly.
Place the NitroFreeze pen on a table, upright (with the clear cap down). Hold the clear cap with one hand and press down the white part of the pen. Once the hissing starts, hold it down for about 2 seconds.
If you are pressing down and there’s no hissing sound, prepare the pen again (step 1).
Step 3 - Using the pen:
Remove the cap from the pen. The tip should have a frosty appearance.
Immediately press down against the wart for:
(For more accurate timings, check the application time in the section below.)
After application, wait two minutes, then dispose of the foam applicator. Don’t reuse the applicator or remove it with your bare hands, as this could reinfect your skin with the wart. After removing, insert a new tip — this will help prepare your pen for the next use.
If you have more than one verruca, you can use NitroFreeze for both (as long as they’re not close to one another). If there’s a distance of more than one inch, it’s safe for you to use. If not, then treat the second wart after two weeks. Using too much NitroFreeze can cause over-freezing, which can damage your skin.
Within 10-14 days of use, the wart should fall off.
Step 4 - Treatment follow-up:
After application, the colour of the skin may change to red or white. You may feel a stinging sensation and a blister may form under the wart for a few hours after use. This is completely normal. If the stinging or aching lasts more than one day, contact your doctor.
Application times:
For your hands, fingers and arms, apply it for 20 seconds or less depending on the size of the wart.
For verrucas on your toes or arches, vary application time by verruca size accordingly:
Calloused verrucas on the heels or balls of your foot should be treated for 40 seconds, regardless of their size.
It's important to make sure you only use NitroFreeze on warts and verrucas. Using it anywhere else can cause frostbite and damage your skin.
Your wart or verruca should fall off within 10-14 days of application. In most cases you’ll only need one treatment, but if after 2 weeks the wart is still there, you may need another treatment. In that case, follow the steps 2-4 again.
If after two treatments the wart doesn't fall off, don’t do a third treatment. Instead, ask your clinician for the next steps.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment: A Randomized, Controlled, Investigator-Blinded, Comparative Study. Dermatology and Therapy, 8(2), 203-216.
Cryotherapy Systems for Wart Removal: A Review of the Clinical Effectiveness, Cost-effectiveness, and Guidelines [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health.
Control of Nitrous Oxide During Cryosurgery. (Accessed: 04/08/23).
Cryotherapy with liquid nitrogen versus topical salicylic acid application for cutaneous warts in primary care: Randomized controlled trial. CMAJ: Canadian Medical Association Journal, 182(15), 1624-1630.
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