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Reviewed on Apr 27, 2026. byDr Alexandra Cristina CowellWriter & Clinical Content ReviewerNext review due on April 24, 2029.
Last updated on Apr 27, 2026.
Product info
Desorex is a progestogen-only mini pill used to prevent pregnancy.
It’s over 99% effective when used correctly (without making mistakes).
It’s a safe choice for women who are breastfeeding.
Price checker
75mcg
£26.95
84 Tablets£26.95
168 Tablets£39.95Save £13.95
336 Tablets£63.95Save £43.85
Prices include:
Express shipping
24 hour shipping by secure courier.
Consultation + Access to our clinicians
Ask our experts anything you like, any time you want.
Desorex is a progestogen-only contraceptive pill that contains the hormone desogestrel. It’s an alternative to the combined pill, which also contains oestogen. Not everyone can use the combined pill due to health factors like migraines with aura or having high blood pressure. For women who can’t use the combined pill, a progesterone only pill or ‘mini pill’ like Desorex is often a safer and more suitable option.
You should take the Desorex mini pill daily around the same time for maximum protection. If you miss taking your pill at the usual time, you have a leeway of about 12 hours to take your tablet and still get its full protection.
How effective is Desorex?
Although the Desorex mini pill is an effective oral hormonal contraception, it works best when used correctly.[1] Desorex desogestrel is over 99% effective if you take it exactly right, so it’s one of the most dependable forms of contraception.
However, like other contraceptives, how well Desorex works is affected by human error. In other words: forgetting to take your pill. ‘Typical use’ of the progestogen only pill (so missing the occasional pill) reduces its efficacy at preventing unplanned pregnancy to around 91%. The more pills you miss, the more your protection is likely to be affected.
If you miss your pill or are worried that you haven’t used Desorex the right way, let one of our clinicians know as soon as you can.
Is Desorex safe?
Yes, especially for women with oestrogen sensitivity. For women who are over 35 or smoke, Desorex has a lower risk of side effects than combined pills.
What’s more, this mini pill is safer for breastfeeding mothers or women who are susceptible to blood clotting. It is also a good choice if you suffer from hypertension, as progestogen-only pills have no effect on blood pressure, and some studies have suggested it can even lower it.[2]
Desorex can give some patients side effects. It can also disrupt your menstrual cycle. But before you stop using it, it’s worth knowing that these side effects tend to pass after a few weeks.
If you feel like you’re not adapting well to your new mini pill, get in touch with our team about switching to a contraceptive that’s more suitable for you.
Treated trusted sources:
Vic.gov.au. (2023). Contraception – the mini pill.Â
Hussain, S.F. (2004). Progestogen-only pills and high blood pressure: is there an association? Contraception, 69(2), pp.89–97. doi:10.1016/j.contraception.2003.09.002.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr Alexandra Cristina Cowell on April 24, 2026. Next review due on April 24, 2029.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
DesorexDesogestrel
How to take Desorex
Follow these instructions directly for the best results and higher efficacy:
Settle on the most convenient time of day to take your first Desorex pill.
If you start taking Desorex on the first day of your period, you’re protected from pregnancy immediately. If you start at any other time in your cycle, you’ll need to use a barrier method (like condoms) or avoid sex for the next seven days.
Try to take a pill every day at the same time until the 28-day tablet strip is over. (Ensure the interval between the pills is 24 hours for effective use).
When you finish with your first Desorex pack, continue on the next strip directly the following day without a pill break.
Desorex allows a 12-hour window period for the contraceptive effects to still work if you forget to take it at your usual time.
When can I start taking Desorex?
You should start your first Desorex tablet on the first day of your period to get immediate protection. If you start on any other days, you need to use a condom or another barrier method of contraception for seven days.
If you’re switching from another combined hormonal contraceptive to Desorex, the latest you can start is on the day following your usual tablet-free, patch-free, ring-free or placebo tablet interval. Barrier methods for the first seven days you take Desorex are also recommended in this instance, too.
What if I miss a Desorex pill?
If you forget to take your mini pill at your usual time, don’t panic. Desorex allows a leeway period of 12 hours, meaning if you take it within this window it will still work just as effectively.
If you’re more than 12 hours late taking your pill:
Take the late pill as soon as you remember (even if this means taking two pills on the same day).
Keep taking your remaining pills at the usual time.
You won’t be protected from pregnancy. Use an extra method of contraception (like condoms) for the next two days (48 hours).
If you had unprotected sex in the two days before missing your pill, you may need emergency contraception.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr Alexandra Cristina Cowell on April 24, 2026. Next review due on April 24, 2029.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
DesorexDesogestrel
Desorex isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.
Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.
DesorexDesogestrel
FAQ: Desorex
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
How does the Desorex pill work?
Answer:
Desorex works by preventing ovulation. The hormone in it, desogestrel, stops your egg cell from ripening. Like other POP pills, the Desorex mini pill also causes the thickening of cervical mucus, preventing sperm movement.
The synthetic progestogen in Desorex (desogestrel) also makes the uterus inhospitable for an egg or sperm cell to survive, which offers you further protection from pregnancy.
Can I take Desorex if I’m breastfeeding?
Answer:
Desorex is safe to use while breastfeeding and doesn’t affect the production or quality of breast milk. While a very small amount of the hormone passes into the milk, there’s no evidence that this has any effect on the growth or development of the baby.[1]
Does Desorex stop periods?
Answer:
Understanding the interaction of Desorex and periods is essential for effective contraceptive use. The first few months of using the pill may cause an irregular menstrual cycle, meaning some women may experience lighter vaginal bleeding, spotting, or none altogether.
Your body may take a while before adapting to the effects of Desorex. So, if using the contraceptive leads to no period for a prolonged time or other severe side effects, seek medical advice.
What other pills is Desorex similar to?
Answer:
Desorex is clinically the same as Cerazette, Feanolla, Cerelle, Hana, and Zelleta since they all contain desogestrel. Desogestrel works by preventing ovulation or thickening cervix mucous to limit sperm movement.
Your personal health needs will determine which mini pill is right for you, and we can help you choose a contraceptive that is suited to you. Our pharmacists are all GPhC-registered, and pride themselves on recommending the best treatments available.
What if I decide I want to get pregnant?
Answer:
Coming off Desorex if you want to get pregnant is easy. Consider finishing your 28-day pill strip instead of stopping mid-month.
You should start ovulating a month or so after you stop taking the Desorex pill. That means you can start trying to get pregnant any time from then.
How is Desorex different from other pills?
Answer:
There are various mini pill brands out there. The difference sometimes lies in the active ingredient, but not always. For example, mini pills Noriday and Norgeston contain norethisterone and levonorgestrel respectively.
Desorex contains the progestogen desogestrel, which is slightly different, and gives you a greater missed pill leeway.
If you forget to take Desorex at your usual time, it will still work as effectively if taken within a window of 12 hours, compared to the 3 hour interval most other pills offer.
Other pills that contain the same active ingredient as Desorex include Cerazette, Cerelle and Zelleta. These should work in the same way, but the packaging and manufacturer will be different.
Do I need a prescription for the Desorex pill?
Answer:
Yes, Desorex is a prescription-only pill. You’ll need to consult with a certified prescriber before you can use it.
Treated trusted sources:
NHS Choices (2024). The progestogen-only pill – Your contraception guide. NHS.
Last updated on Apr 27, 2026.
How we reviewed this page:
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Why this page was updated on Apr 27, 2026
Content checked and updated as part of our 3-yearly periodic review, to ensure accuracy and currentness.
Current version (Apr 27, 2026)
Edited by: The Treated Content Team.Medically reviewed by: Dr Alexandra Cristina Cowell, Writer & Clinical Content Reviewer
May 02, 2023
Published by: The Treated Content Team.Medically reviewed by: Dr Daniel Atkinson, GP Clinical Lead
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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