Gliclazide

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Gliclazide

Gliclazide
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Reviewed on November 10, 2022. by
Dr Daniel Atkinson
GP Clinical Lead
Registered with GMC (No. 4624794)
Next review due on November 10, 2024.
Dr Daniel Atkinson

Product info

  • Gliclazide is a tablet used to manage blood sugar levels.

  • It works by stimulating insulin production in the pancreas to lower blood sugar levels.
  • Gliclazide comes in four different doses: 30mg, 40mg, 60mg and 80mg.

Price checker
£33.95
  • Prices include:
    Express shipping

    24 hour shipping by secure courier.

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    £33.95
    Save £0.00 each order
Gliclazide Gliclazide

What is Gliclazide?

Gliclazide is a daily tablet treatment for type-2 diabetes. It belongs to a class of medicines called sulfonylureas, which are to be used when diet and exercise alone hasn’t been enough to lower your blood glucose (sugar) levels.

Type-2 diabetes normally occurs in adulthood, when your body is unable to process the glucose that you consume as well as it should do, leading to increased concentrations of glucose in your blood. This is usually either because your pancreas doesn’t produce enough insulin, your body doesn’t use the insulin that your pancreas does produce properly, or a combination of both.

How does Gliclazide work?

Sulfonylureas treatments like Gliclazide lower your blood sugar levels by stimulating your pancreas’ beta cells, leading it to produce more insulin. This can increase both your pancreas’ basal and meal-stimulated insulin output.[1]

Increased levels of insulin should help your body to transfer the glucose that you eat from your bloodstream to your cells, leading to lower blood sugar levels.

What doses of Gliclazide are there?

You can get Gliclazide in four different doses: 30mg, 40mg, 60mg and 80mg. The dose that you’re prescribed will depend on both your health and condition. You might be advised to start on a lower dose to see how that controls your blood sugar levels. If it’s not working as hoped at this dosage then it can be increased.

Treated trusted sources:

  1.  go.drugbank.com. (n.d.). Gliclazide. [online]
treated.com This page was written by The Treated Content Team.
Dr Daniel Atkinson
This page was medically reviewed by Dr Daniel Atkinson on November 10, 2022. Next review due on November 10, 2024.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Gliclazide Gliclazide

How to take Gliclazide

You should always take Gliclazide exactly as prescribed by our clinician. Gliclazide should be taken with a glass of water before meals. The standard starting dose is 40-80mg once daily, which can be increased to a maximum of 320mg per day. You shouldn’t take more than 160mg as a single dose, daily doses higher than 160mg will need to be spread across the day.

How long does it take Gliclazide to work?

Gliclazide should start to get to work quickly to stimulate your insulin production when you take it, but it might take several weeks for your HbA1c (the test of your average blood glucose levels) to show an improvement. Studies have shown that it’s most effective when you take it 30 minutes before breakfast.[1]

What should I do if I make a mistake when taking Gliclazide?

Taking too much Gliclazide can lead to hypoglycemia (a blood sugar level that’s too low). If you’ve taken too much Gliclazide, seek medical help straight away. Your symptoms might be helped by having sugary foods or drinks. If you forget to take your dose of Gliclazide you can take it when you remember, as long as it’s not too close to your next dose. If it is, skip that dose and carry on as normal. Don’t double the dose to make up for the missed one.

Treated trusted sources:

  1. Ishibashi, F. and Takashina, S. (1990). The effect of timing on gliclazide absorption and action. Hiroshima Journal of Medical Sciences, [online] 39(1), pp.7–9
treated.com This page was written by The Treated Content Team.
Dr Daniel Atkinson
This page was medically reviewed by Dr Daniel Atkinson on November 10, 2022. Next review due on November 10, 2024.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Gliclazide Gliclazide
Gliclazide Gliclazide

FAQ: Gliclazide

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

How is Gliclazide different from other type-2 diabetes treatments?

Answer:
The main groups of medicines that are used to lower blood sugar are:
  • Metformin
  • Sulfonylureas
  • Pioglitazone
  • DPP-4 inhibitors
  • SGLT-2 inhibitors
  • GLP-1 agonists
  • Insulin
Gliclazide comes under the ‘sulfonylureas’ category of treatment, and you might take it on its own or with another type of treatment. Each of these types of medicine has a slightly different method of action in order to reduce your blood sugar levels. Some treatments improve how your body uses insulin (as is the case with metformin), whereas others increase the amount of glucose that leaves your body through urine (as is the case with SGLT-2 inhibitors, such as Forxiga). Gliclazide works by increasing your pancreas’ insulin production. It’s usually prescribed alongside metformin, or instead of metformin if it isn’t suitable or hasn’t worked for you.

Is Gliclazide similar to any other treatments?

Answer:
There are a few other active ingredients that fall within the sulfonylureas category. These include: glibenclamide, glimepiride, glipizide and tolbutamide. Although these treatments all have the same method of action, they may differ in how well they work for you, as long as how long it takes for them to work and how long they stay in your system for. [1] You can also get branded versions of Gliclazide, such as Diamicron or Zicron. These treatments will work in a much more similar way, as they contain the same active ingredient, but they might differ in dose, appearance or price. Branded treatments are typically a little more expensive than generic ones.

Which dose of Gliclazide should I use?

Answer:
You’ll most likely be advised to start on a low dose of Gliclazide at first, to see how you respond to it. If your clinician decides that it could be working better to control your blood sugar levels then they may increase your recommended dose.

Do I need a prescription for Gliclazide?

Answer:
Yes, you need a prescription for Gliclazide. This is because it’s not suitable for everyone, and your condition and health will need to be monitored whilst you’re taking it.

Treated trusted sources:

  1. Sarkar, A., Tiwari, A., Bhasin, P. and Mitra, M. (2011). Pharmacological and Pharmaceutical Profile of Gliclazide: A Review. [online]

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Registered with GMC (No. 4624794)

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