Jentadueto

What is Jentadueto?

Jentadueto is a combination treatment for type-2 diabetes that works to reduce your blood sugar levels. It’s a tablet that you’ll usually take twice a day, containing two active ingredients that work together to lower your blood sugar: linagliptin, a DPP-4 inhibitor; and metformin - one of the most commonly prescribed treatments for diabetes.

Type-2 diabetes is a condition that you usually develop in adulthood. It usually leads to high concentrations of sugar in your bloodstream (hyperglycemia) which, over time, can lead to an increased risk of you developing further health problems. The hyperglycemia caused by type-2 diabetes is caused by your body no longer producing enough insulin (a key hormone for digesting the sugar that you eat) and your cells losing sensitivity to insulin.

How does Jentadueto work?

Jentadueto’s two active ingredients work together to both encourage your pancreas to secrete more insulin and improve the way that your body uses the insulin it does produce.

Linagliptin blocks the breakdown of incretin hormones in your body - which stimulate your pancreas to produce insulin when you eat. By prolonging the ‘life’ of these hormones, your pancreas produces insulin for longer, which helps your body to continue to store the sugar in your body.

Metformin mainly works by inhibiting glucose production and reducing its reabsorption in the gut. Together, these two active ingredients work together to lower your blood sugar levels and increase your insulin production.

What doses of Jentadueto are there?

Jentadueto is available in two doses. Both doses contain 2.5mg of linagliptin, but the lower dose treatment contains 850mg of metformin, whereas the higher dose treatment contains 1,000mg of metformin.

Our clinician will recommend the best dose for you based on your condition and your health.

How to take Jentadueto

You should always take Jentadueto exactly as instructed by our clinician. You’ll be told how much to take, but the standard dose is usually to take one tablet twice a day, with meals (this will help you to avoid getting an upset stomach).

How long does it take Jentadueto to work?

Jentadueto gets to work pretty quickly when you take it, though it can take several weeks for your HbA1c (the test of your average blood sugar levels over the last 2-3 months) to reduce. You might not feel much difference from taking Jentadueto, but that doesn’t mean that it’s not working, as hyperglycemia doesn’t always give you symptoms.

What should I do if I make a mistake when taking Jentadueto?

If you take too much Jentadueto it can lead to lactic acidosis. As a result, you should seek medical help straight away if you take too much and start to feel unwell. If you forget to take your dose of Jentadueto, you can take it when you remember - so long as it’s not too close to your next scheduled dose. If it is, you should skip that dose and continue as normal. Don’t double your doses to make up for missed ones.