Tolbutamide is a daily diabetes treatment with a potent mode of action to lower your blood sugar levels.
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Tolbutamide is a tablet that works to reduce the high blood sugar levels caused by type-2 diabetes. Type-2 diabetes is a condition that’s typically developed in adulthood when your body no longer produces enough insulin, or when your body is no longer able to properly use the insulin it does produce (or a combination of the two). Insulin is an essential hormone for processing the sugar that you eat, as it moves it from your bloodstream into your cells for it to be used as energy.
As a result, when you have type-2 diabetes your blood sugar level might become too high for long periods of time, which can be bad for your long-term health. Sometimes type-2 diabetes can be managed by diet and exercise alone, especially in its early stages, but when this hasn’t worked treatments are then recommended to help you control your blood sugar levels.
How does Tolbutamide work?
Tolbutamide is a first-generation sulfonylurea - one of a number of types of diabetes treatment. Sulfonylureas, like Tolbutamide, work to reduce your blood sugar by helping your pancreas to secrete more insulin. They do this by binding to receptors on your pancreas’ beta cells, opening your calcium channels and closing your potassium channels. This causes an influx of calcium to move into these cells which then causes more insulin to be released.
More insulin equals more glucose transportation into your cells, which equals lower blood sugar for you.
What doses of Tolbutamide are there?
Tolbutamide tablets are only available in one dose: 500 mg. You might, though, be advised to take more or less tablets based on your health needs, which will dictate your daily ‘dose’. The standard starting dose is to take two tablets per day, which can be increased or decreased depending on how you respond to it.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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How to take Tolbutamide
You should always take Tolbutamide exactly as instructed to by our clinician. To take it, simply swallow your tablet whole with water. Tolbutamide should be taken either with or immediately after your first main meal of the day, or in smaller doses throughout the day with meals.
How long does it take Tolbutamide to work?
Tolbutamide should get to work pretty quickly to start lowering your blood sugar, but it can take weeks to months for it to have a measurable effect. As with any diabetes treatment that you’re taking, you should continue to have regular tests of your blood sugar levels (HbA1c) to make sure that it’s working. If your blood sugar isn’t improving, even after taking the maximum daily dose of Tolbutamide, you’ll likely be prescribed additional or alternative treatment.
What should I do if I make a mistake when taking Tolbutamide?
If you accidentally take too much Tolbutamide, seek medical help straight away. Taking too much Tolbutamide can lead to hypoglycaemia (low blood sugar) which can be dangerous for your health. If you forget your dose of Tolbutamide, you can take it when you remember - so long as it’s not too close to your next scheduled dose. If it is, simply skip that dose and continue with your normal dose schedule. Don’t double up on doses to make up for missed ones.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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FAQ: Tolbutamide
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Is Tolbutamide similar to any other treatments?
Answer:
There are other sulfonylureas you can get which will have a similar mode of action to Tolbutamide. Tolbutamide is a ‘first generation’ sulfonylurea - which means that it’s been around for a while, and newer ‘second generation’ drugs have since been licensed for use.
Tolbutamide isn’t typically prescribed as frequently as newer treatments because while it’s more potent, there’s evidence to suggest that it’s more likely to give you side effects. If you’re prescribed this treatment, though, it’s because a clinician has decided that the benefits it’ll bring to your health are greater than any risks.
How is Tolbutamide different from other treatments for diabetes?
Answer:
Diabetes treatments can come in a range of different types, each of which will work slightly differently to lower your blood sugar. The ‘first-line’ treatment for diabetes is typically metformin, which works by helping your body to use insulin better. But Sulfonylureas like Tolbutamide might then be prescribed to you if metformin on its own hasn’t worked or isn’t suitable for you.
Other types of treatments can include DPP-4 inhibitors, SGLT-2 inhibitors and glitazones. Typically, diabetes treatments involve a bit of trial-and-error, and sometimes a treatment that originally works well might become less effective over time and you’ll need to switch to another treatment or try a few different types at once (or combination treatments).
Do I need a prescription for Tolbutamide?
Answer:
Yes, you need a prescription for Tolbutamide. This is because it’s not a suitable treatment for everyone, and your condition will need to be monitored while you’re using it to make sure that it carries on being safe and effective for you.
Why should I buy Tolbutamide online with Treated?
Answer:
We’ll send you your treatment quickly, discreetly and securely once you’ve talked to us about your health. We know that navigating your diabetes treatment can be a frustrating experience, but our clinicians are on hand to help make the experience a little more hassle-free.
You’ll be able to log into your account and send us a message at any time if you have any questions or concerns, and we’ll send you a handy reminder when your prescription’s due to expire. So you won’t have to worry about running out of the treatment you need.
Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
