This may include:
- Difficulty in breathing
- Swelling of the face, neck and throat
Tablet that eases spasms caused by IBS.
Starting from £35.95
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Buy Colofac online.
Colofac is an antispasmodic treatment for irritable bowel syndrome. It gets to work in around an hour to treat your symptoms, relieving pain and discomfort.
We understand how difficult it can be to live with IBS. That’s why we’ve made it simple to manage your symptoms. Talk to us about your health and get tailored treatment recommendations from our experts.
Starting from £35.95
Here’s what's included in the price:
Consultation
Answer a few questions about your health so we can get to know you better.
Free 24h delivery
Your treatment delivered in secure packaging, the very next day.
Aftercare
We’ll check in with you regularly to see how your treatment is going.
Colofac Mebeverine
What is Colofac?
Colofac is a medicine used to treat the symptoms of irritable bowel syndrome (or ‘IBS’ for short). It’s a common condition that affects your digestive system, causing symptoms like cramps, diarrhoea, constipation and discomfort. Although IBS is a widespread condition, there’s no cure. However, changing your diet and using medication can help to improve your symptoms.
Colofac contains the active ingredient mebeverine hydrochloride, which is a type of antispasmodic. IBS is usually associated with pain, discomfort and spasms in the digestive system. Colofac works by relieving these spasms and other symptoms, allowing you to feel more comfortable.
How does Colofac work?
IBS is a condition that affects your lower gastrointestinal tract, including the small and large intestines. When your intestines spasm (squeeze or tighten), it can cause pain in your lower abdomen. Colofac's active ingredient, mebeverine hydrochloride, is an antispasmodic. This means it relaxes the muscles in your intestines, which stops spasms from occurring.
What doses of Colofac are there?
Colofac comes in 2 different doses: Colofac 135mg tablets and Colofac 200mg Modified-Release capsules.
Both contain the same active ingredient, mebeverine hydrochloride, but the 200mg version is a slow-release tablet. A slow-release tablet releases the drug gradually over a period of time rather than in one go.
Medically reviewed by
Dr Alexandra Cristina Cowell
Writer & Clinical Content Reviewer
on July 12, 2023.
Meet Alexandra Cristina 
This page was medically reviewed by Dr Alexandra Cristina Cowell, Writer & Clinical Content Reviewer on July 12, 2023. Next review due on July 12, 2025.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Colofac Mebeverine
How to take Colofac
Both Colofac 200mg MR capsules and Colofac 135mg tablets should be taken 20 minutes before eating a meal, with a whole glass of water. Do not chew the tablets.
- The dosage depends on the version of Colofac taken.
- The starting dose for Colofac 200mg MR capsules is 1 capsule taken twice a day.
- For Colofac 135mg tablets, 1 tablet is taken 3 times a day. This number can be lowered if symptoms improve, but do not take more than 3 tablets daily.
If you’re taking two tablets a day, take one before breakfast and the other before your evening meal. And for 3 times a day, take one before your breakfast, lunch and evening meal. Children under the age of 10 shouldn’t take Colofac, unless advised.
How long does Colofac take to work?
Colofac usually starts to work around 1 hour after taking it.
Once you feel better, you can stop taking Colofac (but it’s better to ask our clinicians first before stopping). If your symptoms remain the same after 2 weeks have passed, contact our clinician for the next steps.
Making a mistake whilst taking Colofac
If you forget to take a dose, take it when you remember. If it’s nearly time for your next dose, skip the missed dose. Do not take a double dose.
If you have taken more Colofac than required, talk to our clinicians or go to the A&E if you feel any side effects.
Medically reviewed by
Dr Alexandra Cristina Cowell
Writer & Clinical Content Reviewer
on July 12, 2023.
Meet Alexandra Cristina This page was medically reviewed by Dr Alexandra Cristina Cowell, Writer & Clinical Content Reviewer on July 12, 2023. Next review due on July 12, 2025.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Reference Popover #ref1
Treated trusted source
Daniluk, Jaroslaw et al.
(2022). The Efficacy of Mebeverine in the Treatment of Irritable Bowel Syndrome—A Systematic Review. Journal of Clinical Medicine. 11. 1044.
Reference Popover #ref2
Treated trusted source
NHS
National Health Service (2023). Mebeverine. (Accessed: 22 May 2023)
Reference Popover #ref3
Treated trusted source
Patel N, Shackelford K.
Irritable Bowel Syndrome. [Updated 2022 Oct 30]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan
Reference Popover #ref4
Treated trusted source
NHS
National Health Service (2023). Buscopan. (Accessed: 22 May 2023)
This page was medically reviewed by Dr Alexandra Cristina Cowell, Writer & Clinical Content Reviewer on July 12, 2023. Next review due on July 12, 2025.
Your partners in health
Dr Daniel Atkinson
Registered with GMC (No. 4624794)
Meet DanielMs Sanjeda Chowdhury
Registered with GPhC (No. 2202465)
Meet SanjedaMr Craig Marsh
Registered with GPhC (No. 2070724)
Meet CraigWhat’s included? Everything.
Delivery, consultation, treatment. It’s all included in the price.
Colofac Mebeverine
- M/R 200mg
- 135mg
| Quantity | Starting from |
|---|---|
| 60 Capsules | £35.95 |
| 120 Capsules | £55.95 Save £15.95 |
| 180 Capsules | £75.95 Save £31.90 |
| Quantity | Starting from |
|---|---|
| 100 Tablets | £35.95 |
| 200 Tablets | £55.95 Save £15.95 |
| 300 Tablets | £75.95 Save £31.90 |
Buscopan Hyoscine
- 10mg
- Cramps 10mg
- IBS Relief 10mg
| Quantity | Starting from |
|---|---|
| 20 Tablets | £34.95 |
| Quantity | Starting from |
|---|---|
| 20 Tablets | £34.95 |
| Quantity | Starting from |
|---|---|
| 20 Tablets | £34.95 |
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