- feeling or being sick;
- inflammation affecting the heart;
- heartburn;
- vaginal infection; or:
- worsening of a disease called systemic lupus erythematosus (SLE).
For more information on the side effects, check the patient information leaflet.
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Last updated on Sep 17, 2023.
Vibramycin-D is an antibiotic containing doxycycline used to treat mouth ulcers.
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Vibramycin-D is an oral antibiotic that can treat mouth ulcers. It’s in a group of drugs called tetracyclines, which kill bacteria by inhibiting the production of proteins.
Mouth ulcers, also known as canker sores, are white inflamed spots that form in your mouth. They can be caused by many things, like hormonal changes or irritation, and often cause discomfort and pain.[1]Â Even though mouth ulcers don’t always need treatment, taking Vibramycin-D can help prevent them from coming back.
Doxycycline, the active ingredient in Vibramycin-D, is what’s known as a tetracycline. These drugs bind to bacterial ribosomes (the component that makes protein) to stop protein production.[2] Without proteins, bacteria can’t grow, which leads to their eventual death.
It also has additional benefits beyond just being an antibiotic. It has anti-inflammatory properties, which can help reduce swelling by suppressing the action of inflammatory cells. And it can help with tissue damage and the healing of your ulcer, as it has anti-collagenase properties. Collagenase is an enzyme that breaks down tissue. Inhibiting its actions can reduce pain and help speed up the healing process.[3]
Although you can get different doses of doxycycline, Vibramycin-D is only available in 100mg strengths. Vibramycin-D differs slightly from other doxycycline tablets. It’s a dispersible tablet which dissolves when mixed with water. This way, you can use it as a mouth rinse.

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When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
You’ll typically take four tablets a day for three days. Your clinician will decide how long your treatment course should be based on your individual needs. To take Vibramycin-D:
Your ulcer should heal within three days. But it can take longer or quicker, depending on its severity. When you take antibiotics, it’s important that you finish the full course of your treatment. This will help stop the infection from coming back.
If you forget to take a dose, take it as soon as you remember. If it’s nearly time for your next dose, skip it. Don’t take a double dose to make up for a missed one.
If you accidentally swallow it, it’s unlikely you’ll get side effects. You might get a stomach ache, but this usually happens if you take a higher dose.

How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Vibramycin-D isn’t suitable for everyone, and there are some things that you need to be aware of when using it.
Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Last updated on Sep 17, 2023.
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Sep 17, 2023
Published by: The Treated Content Team. Medically reviewed by: Dr Alexandra Cristina Cowell, Writer & Clinical Content ReviewerHow we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Writer & Clinical Content Reviewer
Cristina writes content for Treated, and reviews content produced by our other writers to make sure it’s clinically accurate.
Meet Alexandra CristinaHow we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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