Tablet for non-diabetic hyperglycaemia that lasts longer.

Glucophage SR is the slow-release form of Glucophage. It’s a pill for non-diabetic hyperglycaemia that lowers your blood sugar levels. It also treats type 2 diabetes.
Talk to us about your health, and get recommendations for treatment from our experts. Order Glucophage SR online, on subscription.
Glucophage SR is a pill treatment for non-diabetic hyperglycaemia, also known as pre-diabetes. People affected by non-diabetic hyperglycaemia have blood sugar levels which are higher than normal, but not high enough to be considered type 2 diabetes. Treating raised blood sugar levels early is essential in the prevention of type 2 diabetes, and that’s where medications like Glucophage SR come into play.
It can also help with type 2 diabetes by keeping your blood sugar levels manageable. It’s usually a good option if diet and exercise changes haven’t brought your diabetes under control. Glucophage SR is a prolonged or slow-release form of Glucophage, a medication that lowers your blood sugar. Being slow-release just means that the effects of the medication happen over a long period of time. It also means you don’t have to take the pills as often.
Glucophage SR has the active ingredient metformin hydrochloride. It’s a type of medication called a biguanide, which stops the overproduction of glucose in your liver. It makes an enzyme called AMPK work harder than usual, which allows your cells to respond better to the insulin in your body, so you can manage your blood sugar.
It also helps you reabsorb glucose from your blood. This helps to lower your blood sugar levels and keep them stable. So your hyperglycaemia or type 2 diabetes are brought under control and you can live your life as normal.
Glucophage SR comes in three different size tablets: 500mg, 750mg, and 1000mg tablets. People usually start on the lowest dosage of 500mg. After about two weeks of taking the pills, your dose might be increased. Your clinician will monitor you and check in with you regularly to see how treatment is working out.
The maximum daily dose of Glucophage SR is 2000mg (four 500mg tablets), but most people need a lot less than this. Your clinician might prescribe Glucophage SR by itself or in combination with other antidiabetic medication or insulin, but it depends on the severity of your condition.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Always follow your clinician’s advice on taking Glucophage SR. If you have any questions and you’ve ordered with us, just log into your account and send us a message. There are some general guidelines you can keep in mind too.
Glucophage contains the active ingredient metformin. Metformin has been linked to birth defects in the sons of men who took metformin in the 3 months before conception, so talk to your doctor about alternative treatments if you’re male and thinking of starting a family.
Glucophage SR is a slow-release medication. So your blood sugar levels won’t reduce instantly after you take it, but you should notice a difference within a couple of days. The medication slowly builds up in your system, so it might take four or five days to reach full effectiveness.
If you’ve been taking Glucophage SR for over a week and there’s little difference in your blood sugar levels, contact our clinician. They can review your treatment with you and help you decide if you need a higher dose or a different form of treatment.
If you accidentally take more Glucophage SR than you’re supposed to, don’t worry too much. Glucophage SR overdoses are uncommon and you’re likely to be fine. But if you notice any unusual symptoms after taking the tablets, get emergency medical attention. A clinician can monitor your symptoms and treat them as they occur.
If you forget to take your Glucophage SR tablet when you’re meant to, take your next dose at the usual time. Never take a double dose to make up for missing one.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Registered with GMC (No. 4624794)
Meet DanielRegistered with GPhC (No. 2202465)
Meet SanjedaRegistered with GPhC (No. 2070724)
Meet CraigWe know health, but you know you.
Our experts tell you what’s safe, but you decide what’s best.
Answer a few questions and tell us about yourself. Get tailored advice from our clinicians so you can choose better.
Choose your treatment and how often you have it delivered.
We know things change. It’s the nature of life. We’ll check in regularly to make sure your treatment is still right for you.
Pause. Change. Skip. Start again. Any time you like.
On time
Good
Pleased with the service, very straightforward to order and delivery was very fast.
Everything was quick and professional
Shipping is speedy and the product is amazing.
Excellent company
We're making healthcare more about you. Sign up to our newsletter for personalised health articles that make a difference.
Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
NHS Diabetes Prevention Programme (NHS DPP) Non-diabetic hyperglycaemia Produced by: National Cardiovascular Intelligence Network (NCVIN).
The mechanisms of action of metformin. Diabetologia, 60(9), pp.1577–1585.
Fatal metformin overdose presenting with progressive hyperglycemia. The western journal of emergency medicine,
Metformin and Type 2 Diabetes Prevention. Diabetes Spectrum, 31(4), pp.336–342.
Comparison of Clinical Efficacy and Safety of Metformin Sustained-Release Tablet (II) (Dulening) and Metformin Tablet (Glucophage) in Treatment of Type 2 Diabetes Mellitus. Frontiers in Endocrinology, 12.
Lactic acidosis in patients with diabetes. Polish Archives of Internal Medicine, 123(3), pp.91–97.
Summary for Patients: Preconception Antidiabetic Drugs in Men and Birth Defects in Offspring. Annals of Internal Medicine, 175(5).
We couldn't find what you're looking for.
Here's everything we treat. Or, if you're looking for something we don't have yet, you can suggest something.
If there’s a particular treatment or condition you’re looking for, tell us and we’ll look into it for you.
Submit your question here, or tell us if you’ve found an issue on our site.
We’ll get back to you very soon. We aim to respond to all queries in one working day.
You’re signed up to our newsletter. Keep an eye on your inbox for our latest update.
By clicking 'Subscribe now' you're agreeing to our Privacy Policy.
We’ve sent you an email asking you to confirm your email address.