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Reviewed on Aug 27, 2026. by Dr Daniel Atkinson GP Clinical Lead Registered with GMC (No. 4624794) Next review due on May 19, 2029.
Dr Daniel Atkinson

Last updated on Aug 27, 2026.

Product info

  • Foundayo is a weight loss pill that works in a similar way to Wegovy and Mounjaro.

  • It contains a new GLP-1 drug called orforglipron.
  • It’s taken daily alongside a weight management plan including diet changes and exercise.

Price checker

£184.95 30 tablets
  • Prices include:
    Express shipping

    24 hour shipping by secure courier.

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    £184.95
    Save £0.00 each order
Foundayo Orforglipron

What is Foundayo?

Foundayo is the brand name for orforglipron. It’s a new GLP-1 pill developed by Eli Lilly (the company behind Mounjaro). It’s approved for weight management in adults with obesity or overweight who also have weight-related health conditions like type-2 diabetes or heart disease. It first became available in the UK in August 2026.[1]

What makes it stand out from other weight loss medications is that, unlike other GLP-1 medications, Foundayo is a pill (not an injection) that you can take at any time of day without food or water restrictions.

This is because injectables like Wegovy or Mounjaro are larger molecules called peptides, while Foundayo’s active ingredient is a small, non-peptide molecule. This meant that it could be made into a pill that can be taken by mouth once a day.

How does Foundayo work?

Foundayo (orforglipron) is a GLP-1 receptor agonist, so it works similarly to drugs like Wegovy or Mounjaro. It mimics the GLP-1 hormone your body naturally produces to regulate your appetite, blood sugar, and digestion, helping to:[2]

  • Support weight loss by reducing hunger cues and calorie intake
  • Slow stomach emptying, which can help you feel full for longer after eating
  • Reduce appetite and food cravings, especially for foods that are high in fat and sugar
  • Improve blood sugar control by helping your body to use glucose more effectively and increasing insulin production
  • Lower blood pressure and improve your heart health

What doses of Foundayo are there?

There are six doses of Foundayo available:

Dose Color Shape
0.8mg Pink Round
2.5mg Light yellow Round
5.5mg Grayish purple Round
9mg Pink Modified oval
14.5mg Light yellow Modified oval
17.2mg Grayish purple Modified oval

All doses are pills that you take once a day, at any time.

You’ll typically start by taking the 0.8mg dose once daily for at least 30 days. If you tolerate it well, your doctor may advise that you increase the dose to 2.5mg daily.

After that, depending on your response to the medication, your dose may be titrated every 30 days until you reach the highest dose you feel comfortable on, up to a maximum of 17.2mg per day. However, not everyone needs the highest dose. Many people find that a lower dose works just fine for them.

Treated trusted sources:

  1. Medicines and Healthcare products Regulatory Agency. (2026). UK first in Europe to authorise orforglipron for weight management and type 2 diabetes. Gov.uk. Aug 10.
  2. Zheng, Z., et al. (2024). Glucagon-like peptide-1 receptor: mechanisms and advances in therapy. Signal Transduction and Targeted Therapy, 9(1), pp.1–29.
treated.com This page was written by The Treated Content Team.
Dr Daniel Atkinson 312
This page was medically reviewed by Dr Daniel Atkinson on May 19, 2026. Next review due on May 19, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Foundayo Orforglipron

How to take Foundayo

You’ll be advised to take Foundayo once a day by mouth:

  • With or without food
  • At any time of day
  • With a glass of water, which may help reduce side effects and keep you hydrated

Don’t break, crush, or chew the pill, and don’t take more than one pill a day.

You’ll also typically be advised to follow a dose escalation plan, where the dose is gradually increased over time:

  • Start with 0.8mg once daily for at least 30 days
  • If you tolerate this dose well, increase your daily dose to 2.5mg
  • After another 30 days, you can increase to 5.5mg once daily
  • After this, you can increase the dose gradually at intervals of at least 30 days, depending on how well you tolerate the medication, up to the maximum available dose of 17.2mg daily
treated.com This page was written by The Treated Content Team.
Dr Daniel Atkinson 312
This page was medically reviewed by Dr Daniel Atkinson on May 19, 2026. Next review due on May 19, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Foundayo Orforglipron

Viagra isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.

Foundayo Orforglipron

FAQ: Foundayo

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

How does Foundayo compare with other weight loss treatments?

Answer:
injection like other weight loss medications (injectable Wegovy and Mounjaro, for example). That’s mostly due to the fact that orforglipron is a small molecule which can be made into a pill, in comparison to the active ingredients in Wegovy and Mounjaro, which are peptides (much larger molecules that are better absorbed when injected).

Orforglipron is also generally easier and cheaper to manufacture than injectable GLP-1s, which could lower costs and improve availability. And early studies have suggested it may remain effective for longer before the body becomes less responsive to treatment.[1]

Here are the differences between Foundayo and other popular weight loss treatments:

Orforglipron vs. tirzepatide (Mounjaro)


Tirzepatide currently appears to produce greater overall weight loss in clinical trials.[2] However, Foundayo may be a more practical option for people who prefer pills over injections.

Orforglipron vs. semaglutide (Wegovy)


Studies suggest that orforglipron (Foundayo) may lead to greater weight loss than oral semaglutide (the active ingredient in the Wegovy pill)[3]:

Orforglipron: 9.2% at 36mg and 6.7% weight loss at 12mg
Oral semaglutide: 5.3% at 14mg and 3.7% weight loss at 7mg

Many people may also find it easier to take, as it doesn’t need to be taken on an empty stomach, like the Wegovy pill, and then wait for at least 30 minutes before eating or drinking.

Orforglipron vs. retatrutide


Retatrutide (also sometimes called Triple-G, because it targets three hormone receptors) is an injectable treatment that has shown promising weight loss results.[4] But it’s still being evaluated in clinical trials, and is not yet available on the market.

Will I need a prescription for Foundayo?

Answer:
Yes, you’ll need a prescription from your doctor to take Foundayo. Like most other weight loss drugs, it’s usually only recommended for people with obesity or those who are overweight and also have other weight-related health conditions (such as high blood pressure or type 2 diabetes). So a medical professional needs to check that it’s suitable for you.

And once they decide that Foundayo is right for you, it also needs ongoing monitoring, especially at the start of the treatment and when adjusting doses. This is to make sure that the medication is working safely for you and any side effects are well-managed.

Will I get side effects using Foundayo?

Answer:
While this doesn’t happen for everyone, you may get side effects from taking Foundayo. Like other GLP-1 medications, the most common side effects are gastrointestinal issues, like nausea, vomiting, diarrhea, constipation, stomach pain, bloating, passing gas, and acid reflux.[5]

Headaches, fatigue, and hair loss have also been reported in 5% to 9% of people taking Foundayo in clinical trials.[6]

These side effects usually become more noticeable at higher doses. But the good news is that they tend to improve over time as your body gets used to the medication or a new dose.

The above are common adverse reactions. For less common adverse reactions, check the patient information leaflet that comes with your medication. Examples include:

  • Acute pancreatitis

  • Severe gastrointestinal problems

  • Retinopathy (eye problems) in people with type 2 diabetes

  • Kidney issues

  • Low blood glucose levels


And if there’s anything unclear about your symptoms or side effects, double-check with a medical professional.

How effective is Foundayo for weight loss?

Answer:
Clinical trials have found orforglipron, the active ingredient in Foundayo, to be very effective for weight loss when combined with a reduced-calorie diet and exercise.

Over 36 weeks, people taking the 12mg dose lost an average of 9.4% of their body weight (around 21.6lbs). By comparison, the placebo group lost an average of just 2.3% of their body weight, or around 5.3lbs.[7]

Another 72-week clinical trial has found that people taking the maximum 17.2mg dose of Foundayo lost an average of 11.1% of their body weight (around 25lbs). Lower doses have also led to significant results, with average body weight loss of 8.3% on the 9mg dose and 7.4% on the 5.5mg dose, while the placebo group only lost 2.1% of their body weight over the same period (5.3lbs).[8]

Treated trusted sources:

  1. Wharton, S., et al. (2023). Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults with Obesity. The New England Journal of Medicine, 389(10), pp.877-888.
  2. Jastreboff, A.M., et al. (2022). Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal of Medicine, 387(3), pp.205-216.
  3. Rosenstock, J., et al. (2026). Efficacy and safety of once-daily oral orforglipron compared with oral semaglutide in adults with type 2 diabetes (ACHIEVE-3): a multinational, multicentre, non-inferiority, open-label, randomised, phase 3 trial. The Lancet, 407(10534), pp.1147-1160.
  4. Jastreboff, A.M., et al. (2023). Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial. The New England Journal Of Medicine, 389(6), pp.514-526.
  5. Dutta, D., et al. (2024). Orforglipron, a novel non‐peptide oral daily glucagon‐like peptide‐1 receptor agonist as an anti‐obesity medicine: A systematic review and meta‐analysis. Obesity science & practice, 10(2), e743.
  6. Eli Lilly and Company (2026). FOUNDAYO (orforglipron) tablet, film coated [Label].
  7. Wharton, S., et al. (2023). Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults with Obesity. The New England Journal of Medicine, 389(10), pp.877-888.
  8. Wharton, S., et al. (2025). Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment. New England Journal of Medicine, 393(18), pp.1796-1806.

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