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Mysimba helps you to lose weight by working on the receptors of the brain that control appetite. Together with a healthy diet and exercise, it can help you lose weight.
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Mysimba is a weight loss tablet that works in the brain to alter feelings of hunger and how your body spends energy. Youโll start off on a low dose of one tablet per day, and gradually increase this to two tablets twice a day over the first four weeks.
When itโs used alongside a calorie controlled diet and regular exercise, it can be very effective at helping people lose weight. In clinical trials, people taking Mysimba had a โmeanโ (average) weight loss of 5.4% when taking it over 54 weeks, and a mean weight loss of 8.1% when it was combined with behavioural counselling.
Mysimba is a medicine thatโs only available on prescription, so youโll need to have a consultation with us about it before you use it.
Mysimba weight loss tablets contain naltrexone and bupropion, and these work on the specific area of the brain that controls how much food you eat and how energy is spent. By affecting cravings for food, it makes it less likely youโll overeat, which can lead to significant weight loss if you make adjustments to your lifestyle too.
The ingredient bupropion is also used in some antidepressant medications, as well as a popular stop smoking treatment called Zyban. So Mysimba is quite different to the weight loss tablet Orlistat, which affects how much fat you take up from food.
Mysimba has been shown to work well in clinical trials, and be even more effective when used alongside weight loss management counselling. In a study of people taking it over 56 weeks, there was an average weight loss of 5.4%, and an average weight loss of 8.1% in people who also had behavioural support.
In a combined analysis of studies, up to 42% of people taking Mysimba over 56 weeks lost at least 5% of their body weight, and up to 22% lost 10% of their body weight. So it has proven to be effective for a sizeable portion of people that take it.
European Medicines Agency. Mysbimba. EPAR summary for the public. Science Medicines Health. 2015.ย
Mysimba 8 mg/90 mg prolonged-release tablets - Summary of Product Characteristics (SmPC) - (emc).ย [Accessed 22 Mar. 2022].
Patel, K. et al. Taylor and Francis Online. Clinical Focus: Cardiovascular Disease - Review. Safety and tolerability of new-generation anti-obesity medications: a narrative review. 2017.
Read the leaflet that comes with the medication before you take Mysimba. If thereโs anything you arenโt sure about, let us know.
If you forget your Mysimba dose, donโt worry โ just take your next dose as normal and continue the course. Donโt take double the amount at your next dose, because this wonโt have any benefit and increases the risk of side effects.
If youโre having trouble remembering to take the medication, you might find it useful to set a daily reminder to take it at specific times, or take it with a specific meal each day.
If youโve taken too much Mysimba, you should seek immediate medical attention. Go to your nearest hospital and take your Mysimba packaging with you if possible.
Taking the tablets at the same time each day can help you to remember when to take your tablet and prevent you from taking too much by accident.
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