A clinically proven weight loss pill.

Mysimba helps you to lose weight by working on the receptors of the brain that control appetite. Together with a healthy diet and exercise, it can help you lose weight.
Get the treatment that works best for you. Talk to us to get personalised treatment suggestions. Order Mysimba online and have it delivered to you on subscription.
Mysimba is a weight loss tablet that works in the brain to alter feelings of hunger and how your body spends energy. You’ll start off on a low dose of one tablet per day, and gradually increase this to two tablets twice a day over the first four weeks.
When it’s used alongside a calorie controlled diet and regular exercise, it can be very effective at helping people lose weight. In clinical trials, people taking Mysimba had a ‘mean’ (average) weight loss of 5.4% when taking it over 54 weeks, and a mean weight loss of 8.1% when it was combined with behavioural counselling.
Mysimba is a medicine that’s only available on prescription, so you’ll need to have a consultation with us about it before you use it.
Mysimba weight loss tablets contain naltrexone and bupropion, and these work on the specific area of the brain that controls how much food you eat and how energy is spent. By affecting cravings for food, it makes it less likely you’ll overeat, which can lead to significant weight loss if you make adjustments to your lifestyle too.
The ingredient bupropion is also used in some antidepressant medications, as well as a popular stop smoking treatment called Zyban. So Mysimba is quite different to the weight loss tablet Orlistat, which affects how much fat you take up from food.
Mysimba has been shown to work well in clinical trials, and be even more effective when used alongside weight loss management counselling. In a study of people taking it over 56 weeks, there was an average weight loss of 5.4%, and an average weight loss of 8.1% in people who also had behavioural support.
In a combined analysis of studies, up to 42% of people taking Mysimba over 56 weeks lost at least 5% of their body weight, and up to 22% lost 10% of their body weight. So it has proven to be effective for a sizeable portion of people that take it.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Mysimba 8 mg/90 mg prolonged-release tablets - Summary of Product Characteristics (SmPC) - (emc). [Accessed 22 Mar. 2022].
European Medicines Agency. Mysbimba. EPAR summary for the public. Science Medicines Health. 2015.
Patel, K. et al. Taylor and Francis Online. Clinical Focus: Cardiovascular Disease - Review. Safety and tolerability of new-generation anti-obesity medications: a narrative review. 2017.
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112 Tablets | £143.95 |
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336 Tablets | £385.95 Save £45.90 |
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84 Capsules | £56.95 |
168 Capsules | £97.95 Save £15.95 |
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84 Capsules | £61.95 |
168 Capsules | £107.95 Save £15.95 |
252 Capsules | £149.95 Save £35.90 |
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1 Pens | £86.95 |
2 Pens | £160.95 Save £12.95 |
3 Pens | £241.95 Save £18.90 |
4 Pens | £287.95 Save £59.85 |
5 Pens | £344.95 Save £89.80 |
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84 Capsules | £61.95 |
168 Capsules | £112.95 Save £10.95 |
252 Capsules | £158.95 Save £26.90 |
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Weight loss: Here are some other options.
A low dose version of Xenical. It reduces the amount of fat being absorbed by your body.
Just like Xenical but without the branding. Can reduce fat absorption by up to 33%.
Highly effective daily injection. It interacts with your brain to make you feel more full.
Weekly injection for weight loss. Expected spring/summer 2023.
Branded version of Orlistat. It can help reduce how much fat is absorbed by the body.
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