Because it’s a second generation antihistamine, Levocetirizine has been formulated in a way so that it doesn’t easily cross the blood-brain barrier. As a result, unlike first generation antihistamines, it doesn’t interrupt histamine receptors in your brain, making it far less likely to cause drowsiness.[1]
Some people still get drowsy when they take Levocetirizine, though. So if you’ve taken it and feel drowsy, you should avoid driving or operating heavy machinery.
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Levocetirizine is a once-a-day tablet used for allergies like hay fever and hives.
- It works by binding to your histamine receptors to stop them from causing symptoms.
- It starts working within an hour and lasts for up to 28 hours.
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Levocetirizine Levocetirizine
What is Levocetirizine?
Levocetirizine is a tablet that you take once a day to help you with common allergy conditions and symptoms, such as hay fever and hives. It’s an antihistamine, which means that it can get to work quickly to help you with your symptoms, and stays in your system for the full day.
Levocetirizine is a second generation antihistamine, so, unlike early antihistamines, it’s less unlikely that it’ll make you drowsy (although some people still do feel drowsy when they take Levocetirizine).
How does Levocetirizine work?
When your body detects something that it considers a threat, it produces a chemical called histamine to try and keep it out. In the case of allergic reactions, your body is reacting to something that it wrongly considers a threat, such as pollen.
Antihistamines, like Levocetirizine, work by binding to your histamine receptors and stopping histamine from causing your symptoms.
What doses of Levocetirizine are there?
There’s only one dose of Levocetirizine: 5mg. If it’s not working for your symptoms at this dose, please let our clinician know. You might need to try another treatment.
This page was written by The Treated Content Team. 
This page was medically reviewed by Dr Daniel Atkinson on January 13, 2023. Next review due on January 10, 2025.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Levocetirizine Levocetirizine
How to take Levocetirizine
You should always take Levocetirizine exactly as prescribed by our clinician. It’s not recommended for children under six. To use Levocetirizine:
- swallow the tablet whole with water
- take it with or without food
- the recommended dose is one tablet per day
How long does it take Levocetirizine to work?
Levocetirizine gets to work pretty quickly to treat your symptoms. You should start feeling the effects after around an hour, and it reaches its peak approximately six hours after taking it. [1] It stays in your system for around 28 hours as well, so if you take it around the same time each day it should prevent your symptoms from setting in.
What should I do if I make a mistake when taking Levocetirizine?
Taking too much Levocetirizine can be harmful for your health and give you some unpleasant side effects. Seek medical help and advice if you’ve accidentally taken too much. If you forget your dose of Levocetirizine then skip it and take your next dose at the usual time. Don’t double up on doses to make up for missed ones.
Treated trusted sources:
- Nettis, E., Calogiuri, G.F., Di Leo, E., Cardinale, F., Macchia, L., Ferrannini, A. and Vacca, A. (2008). Once daily levocetirizine for the treatment of allergic rhinitis and chronic idiopathic urticaria. Journal of Asthma and Allergy, 2, pp.17–23.
This page was written by The Treated Content Team. This page was medically reviewed by Dr Daniel Atkinson on January 13, 2023. Next review due on January 10, 2025.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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