Effective tablet for angina and hypertension.

Istin is a tablet that lowers your blood pressure and reduces symptoms of angina.
Talk to us about your health if you have concerns about angina or high blood pressure. Find out if Istin is safe for you and order Istin online.
Istin is one of the brand names of a drug called amlodipine. It’s a prescription only medication that’s used to treat two common conditions – angina and high blood pressure.
Angina is the name used to describe a pain that starts in your chest and sometimes spreads elsewhere. It’s caused by reduced blood flow to your heart muscles, and while it isn’t usually life-threatening, it is a warning sign that you could be at risk of experiencing a heart attack or a stroke. The pain of angina can vary from a tightness that makes it feel hard to breathe, to a dull, heavy discomfort that spreads to your arms, shoulders, back or jaw. An angina attack is usually brought on by stress or physical activity, and stops within a few minutes of resting.
High blood pressure, also known as hypertension, is when the force of the blood pumping through your arteries is too high. The more that your heart pumps and the narrower your arteries, the higher your blood pressure will be. People who have an unhealthy lifestyle are more likely to develop high blood pressure. This includes those who are overweight, eat too much salt, fat and sugar, smoke, or drink too much alcohol. Stress is also a big factor in high blood pressure. If you have high blood pressure, it can make angina symptoms worse. High blood pressure also increases your risk of serious health problems including heart disease, stroke and a heart attack.
The active ingredient in Istin, amlodipine, is what’s known as a ‘calcium channel blocker’. Calcium channel blockers work by causing the muscle cells in your artery walls to relax. This enables your arteries to widen, letting blood flow through them more easily. This means that the heart doesn’t have to work as hard to push blood around the body, reducing blood pressure to a healthy level. Having a lower blood pressure reduces your risk of a number of health problems, including angina.
Istin is available in two doses:
The dose that you’ll be prescribed will be based on your personal circumstances, such as your age, how high your blood pressure is, and if you have any other health conditions (such as any issues with your liver or kidneys). But typically you’ll start on the lower dose of 5mg and be monitored - with the dosage being increased if the starting dose isn’t working well enough. You might have to stay on the lower dose if you have some underlying conditions or you’re struggling with side effects.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Istin can be taken with or without food, and should be taken orally, once per day. It can be helpful to take it at the same time every day so that it becomes routine, making you less likely to forget a dose.
Istin tablets should always be swallowed whole with water. However if you struggle to swallow tablets, you can dissolve the tablet in a glass of water first, so long as you drink the whole glass immediately afterwards.
You shouldn’t eat or drink lots of grapefruit or grapefruit juice when you’re taking Istin tablets. This is because grapefruit can increase the concentration of Istin in your body, making side effects more likely.
Istin starts to work immediately, but it may take several weeks for your blood pressure to reach its lowest levels. Because high blood pressure rarely causes any noticeable symptoms, you probably won’t realise that your blood pressure has come down unless you get it checked. If you suffer from angina, your symptoms and the frequency of your angina attacks should start to reduce within a few weeks.
Always take Istin exactly as you’ve been told to by our clinician.
If you accidentally take more Istin than you should, you should seek medical help straight away, and don’t drive. Excessive levels of amlodipine can cause drowsiness, which makes driving dangerous. Make sure you take your Istin packaging with you, along with any remaining medication.
If you have missed a dose of Istin, you should take it as soon as you remember. However, if it’s nearly time for your next dose, you should skip the missed dose and continue as normal. Never take more Istin to ‘catch-up’ on the dose that you missed.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Overview - High Blood Pressure (hypertension). [online] NHS.
Clinical safety and efficacy of once-a-day amlodipine for chronic stable angina pectoris. The American Journal of Cardiology, [online] 62(9), pp.518–522.
Amlodipine in hypertension: a first-line agent with efficacy for improving blood pressure and patient outcomes. Open Heart, [online] 3(2), p.e000473.
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Meet RuaraidhDelivery, consultation, treatment. It’s all included in the price.
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56 Tablets | £91.95 Save £23.95 |
84 Tablets | £149.95 Save £23.90 |
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28 Tablets | £66.95 |
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28 Tablets | £22.95 |
56 Tablets | £34.95 Save £10.95 |
84 Tablets | £45.95 Save £22.90 |
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28 Tablets | £22.95 |
56 Tablets | £34.95 Save £10.95 |
84 Tablets | £45.95 Save £22.90 |
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28 Patches | £53.95 |
56 Patches | £82.95 Save £24.95 |
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28 Patches | £53.95 |
56 Patches | £89.95 Save £17.95 |
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100 Tablets | £48.95 |
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180 Sprays | £49.95 |
360 Sprays | £81.95 Save £17.95 |
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180 Sprays | £45.95 |
200 Sprays | £51.95 |
360 Sprays | £68.95 Save £22.95 |
400 Sprays | £74.95 Save £27.16 |
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Angina: Here are some other options.
Once daily tablet that lowers blood pressure. Generic version of Istin.
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Stop attacks with a fast-dissolving tablet. Take before exercise and get back your freedom.
Fast-acting preventative and emergency spray for angina. So it stops and treats attacks.
Branded version of Glyceryl Trinitrate. Works quickly in the body to prevent and tackle attacks.
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