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What Is The Best Contraceptive For Perimenopause?

What Is The Best Contraceptive For Perimenopause?

Perimenopause, the transitional stage before you reach menopause, typically starts in your mid-40s, but it can begin in your late 30s or early 40s. Despite the irregular periods during this time, you can still get pregnant. So it’s recommended to use effective contraception until you reach menopause.

There is no singular best contraception for perimenopausal women. Your doctor will look at your medical history, followed by your risks of health conditions. Aside from that, you won’t be limited by your age when choosing a contraceptive.

Daniel Atkinson
Medically reviewed by
Daniel Atkinson, GP Clinical Lead
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Medically reviewed by
Dr Daniel Atkinson
GP Clinical Lead
on Jun 19, 2024.
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Last updated on Jun 18, 2024.

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  • Perimenopausal women can use contraception to avoid pregnancy – it comes down to medical history and health risks, not age.
  • Progesterone-only methods for perimenopause include the implant, injection, mini-pill, and coil – but not all are suitable for everyone.
  • Combined methods can regulate menstrual cycles and relieve symptoms, but may pose risks if you smoke or have certain health conditions.
  • Non-hormonal contraceptives, like condoms and copper IUDs provide effective contraception without hormonal side effects.

What contraception is available during perimenopause?

While there aren’t specific restrictions on contraception during perimenopause, your choices can be limited if you have certain medical conditions or health risks. For instance, hormonal contraceptives should be avoided if you’ve had breast cancer. Instead, your doctor will likely advise you to use non-hormonal methods, such as the copper IUD.

The only contraceptive method that’s not recommended for perimenopausal women is fertility awareness-based methods (FABM). It’s a natural contraceptive method that tracks your vaginal mucus and temperature daily to find your most fertile window where you would avoid sexual intercourse. However, during perimenopause, hormonal fluctuations can cause irregularities in your ovulation and menstrual cycle, making it difficult to accurately predict fertile days. As a result, FABM is an unreliable form of contraception and should be avoided to prevent unintended pregnancy.

Progesterone-only methods

Progesterone-only methods only contain the synthetic hormone progesterone. There are four main types: the implant, injection, mini pill, and hormonal intrauterine system (IUS), commonly known as the hormonal coil. This type prevents pregnancy by stopping the process of ovulation and thickening the cervical mucus, making it difficult for sperm to reach an egg.

The IUS is particularly useful as it is a very effective contraceptive; once it has been fitted you can forget about it for five years and it can also play an important role in HRT if you decide you would like this to help with menopausal symptoms.

Most women can safely use progesterone-only contraception, but some can’t, such as those who:

  • had a stroke,
  • have a liver condition,
  • had breast cancer,
  • any cardiovascular illnesses, or
  • unexplained vaginal bleeding.

The implant

The implant is a long-acting reversible contraception (LARC) method that lasts approximately three years. It consists of a tiny plastic rod inserted under the skin of the upper arm, releasing small amounts of progesterone to prevent pregnancy. It’s over 99% effective if replaced every three years.

One of the primary advantages of the implant is its long-lasting nature, making it a hassle-free method that won’t require daily or monthly management. It can also help regulate your hormones, potentially reducing perimenopausal symptoms like mood swings and hot flashes.

However, some women may experience irregular bleeding as a side effect of the implant. This can make it difficult to track hormone levels and menstrual patterns during perimenopause.

The injection

The contraceptive injection, known commonly by the brand name ‘Depo-Provera’, is a LARC that lasts 8-13 weeks. Compared to other LARCs, it requires repeat injections every few months. It contains the active drug medroxyprogesterone acetate (MPA), which is a synthetic version of progesterone.

MPA can help relieve some menopausal symptoms and lighten your periods. But some studies have found that MPA can negatively impact bone density and oestrogen levels.

Perimenopausal women already face the risk of bone fractures and osteoporosis, due to declined oestrogen levels. MPA may further lower oestrogen levels and bone density, possibly increasing your risk of osteoporosis. This was found in a study where women using MPA had a significant decrease in bone density, although the results did find the density returned to pre-MPA levels after discontinuation.

However, another study concluded that the use of MPA during menopause did not result in decreased bone density. Ultimately, individual responses to MPA can vary, so it’s hard to predict how MPA will affect you.

The hormonal coil

The hormonal coil or intrauterine system (IUS) is another LARC method that can last 3 to 8 years, depending on the brand. It’s a plastic T-shaped device that’s inserted into your uterus and is over 99% effective in preventing pregnancy. It comes in three doses: 13.5 mg, 19.5 mg and 52 mg, allowing flexibility to adjust the dose to your individual needs.

An IUS can be particularly beneficial for perimenopausal women experiencing heavy menstrual bleeding. Its ability to decrease endothelial growth leads to lighter, pain-free periods. One study showed that perimenopausal women using the IUS experienced a significant reduction in heavy periods compared to those using MPA.

Furthermore, depending on the brand, some IUS, such as the Mirena coil, can offer both contraceptive and HRT effects. This allows you to get the benefits of HRT while simultaneously having effective pregnancy protection.

Progesterone-only pills

Progesterone-only pills (POP), also known as mini-pills, are progestin-only pills suitable for individuals who can’t take oestrogen. They need to be taken daily, which can be slightly less convenient than other progesterone-only methods. Mini pills come in various doses and with different active ingredients, so if one doesn’t work well for you, there are other options that you can try.

For menopausal women who cannot use oestrogen, mini pills offer a safer alternative with a lower risk of high blood pressure, blood clots, and stroke compared to combined hormonal contraceptives. Additionally, POPs are less likely to cause oestrogen-related side effects such as breast tenderness, bloating, and headaches, making them more tolerable for some individuals.

However, mini pills may be less effective in managing menopausal symptoms due to the lack of oestrogen. So you might not notice much improvements in your menopausal symptoms, such as vaginal dryness.

Contraception: Here's what we've got.

Blister strip of Zelleta tablets

Zelleta

Desogestrel

Same hormone and same dose as Cerazette and Cerelle. 12 hour window if you're late taking it.

  • Starting from £25.95
Blister strip of Cerelle tablets

Cerelle

Desogestrel

Very similar to Cerazette and Zelleta. 28 day pill. 12 hour leeway if you take it late.

  • Starting from £29.95
Blister strip of Cerazette tablets

Cerazette

Desogestrel

Probably the most well-known brand of mini pill. 12 hour leeway if you're late taking it.

  • Starting from £33.95
Blister strip of contraceptive pills

Hana

Desogestrel

Similar to Cerazette, Zelleta and Cerelle, but you don't need a prescription for it.

  • Starting from £39.95
Slynd

Slynd

Drospirenone

Progesterone-only pill with a 24-hour missed pill window.

  • Starting from £49.95
Large Desorex Blister Pack

Desorex

Desogestrel

Mini pill taken every day to prevent pregnancy. A good option if you’re sensitive to oestrogen.

  • Starting from £26.95
Yellow blister pack containing 35 small white tablets

Norgeston

Levonogestrel

Slightly different type of mini pill that contains levonorgestrel, and comes in strips of 35.

  • Starting from £26.95
Blister strip of Noriday tablets

Noriday

Norethisterone

Norethisterone-based alternative. 3 hour window if you're late taking it.

  • Starting from £25.95
Desogestrel blister

Desogestrel

Desogestrel

Contains a small amount of progestogen to prevent pregnancy. Can be used while breastfeeding. 12-hour window if you forget to take it.

  • Starting from £36.95
Generic

Lovima

Desogestrel

Desogestrel pill that works just like Cerazette and Cerelle, but doesn't need a prescription.

  • Starting from £64.95
Silver blister pack containing 28 small round white tablets

Feanolla

Desogestrel

Desogestrel-based mini pill, very similar to Zelleta, Cerelle and Cerazette.

  • Starting from £27.95

Combined contraceptives

Combined contraceptive methods contain a combination of two synthetic hormones: oestrogen and progesterone. There are three main types: the patch, combined pill, and contraceptive ring. These combined contraceptives work similarly to progestin-only methods by thickening the cervical mucus, which prevents the sperm from reaching the egg, and also by inhibiting the maturation of the egg, preventing ovulation.

Generally, combined contraceptives are safe for menopausal women, but if you are over 35 and at risk of getting a stroke, ischemic heart disease and cardiovascular disease, then it’s best to avoid them. You should also avoid them if you have high blood pressure, or smoke more than 15 cigarettes a day. Combined contraceptives aren’t suitable for women over 50 years.

The patch

The contraceptive patch is a square sticky patch that’s applied to your skin each week. It’s commonly known by the brand name Evra, which contains ethinyl estradiol and norelgestromin and comes in two doses. It can be used up until the age of 50.

For perimenopausal women, the contraceptive patch can help regulate hormonal fluctuations, which can alleviate menopausal symptoms, such as hot flashes, night sweats, vaginal dryness and mood swings. This can make the transition to menopause much smoother.

However, in some cases, you might get oestrogen-related side effects while taking it, such as nausea and breast tenderness. Generally, they go away as your body adjusts, but for some individuals, they can worsen during perimenopause. And like most hormonal contraceptives, it can mask menopausal changes making it difficult to understand your body during the transition.

Contraception: Here's what we've got.

Square silver packet containing one pink skin patch

Evra

Ethinylestradiol/Norelgestromin

A bit like a skin plaster, works in the same way as the combined pill. Changed weekly with a 7 day break every month.

  • Starting from £51.95

Combined pill

Combined pills are available in different doses and combinations of synthetic oestrogen and progesterone. So, if one combined pill doesn’t suit your individual needs, there are alternatives with different ingredients that could potentially offer better compatibility and effectiveness.

Combined pills can ease your transition into menopause by restoring the regularity of your menstrual cycle, improving menopausal symptoms, like hot flushes, night sweats and vaginal dryness and preventing endometrial hyperplasia (irregular thickening of the uterine lining).
This prevents irregular bleeding and reduces the risk of endometrial cancer. You’ll also have a regular bleed during the pill-free week every month, which further helps regulate your menstrual cycles and prevents abnormal bleeding.

Furthermore, more benefits were found with a higher dose of oestrogen (30–35 mcg) compared to the lower dose (20 mcg), including controlled bleeding and improvement in hormonal migraines.

However, the continuous use of combined oral contraceptives during menopause should be discussed with your doctor as it can lead to increased health risks. So it’s important to stop taking combined oral contraceptives at the appropriate time (and definitely before the age of 50) and look for suitable alternatives.

Contraception: Here's what we've got.

Drovelis

Drovelis

Drospirenone and estetrol monohydrate.

Effective pill to prevent pregnancy. Can make periods lighter and less painful.

  • Starting from £39.95
Blister strip of Elevin tablets

Elevin

Ethinylestradiol/Levonorgestrel

Safest category combined pill, with a lower risk of oestrogen side effects. Very similar to Levest.

  • Starting from £63.95
Blister strip of Rigevidon tablets placed diagonally

Rigevidon

Ethinylestradiol/Levonorgestrel

Very similar to Microgynon and Levest. Safest category pill that helps with heavy menstrual bleeds.

  • Starting from £25.95
Blister strip of Yasmin tablets

Yasmin

Ethinylestradiol/Drospirenone

Well known pill that reduces PMS symptoms and can help to make your periods more regular.

  • Starting from £41.95
Back of Microgynon blister tablets

Microgynon

Ethinylestradiol/Levonorgestrel

Safest category pill that reduces heavy bleeding. Same hormone mix as Levest and Rigevidon.

  • Starting from £27.95
Blister strip of Levest tablets

Levest

Ethinylestradiol/Levonorgestrel

Safest category pill, helps with heavy menstrual bleeding. Very similar to Rigevidon and Microgynon.

  • Starting from £26.95
Blister strip of Eloine tablets

Eloine

Ethinylestradiol/Drospirenone

Like Yasmin but in a lower dose. 28 day pill you take without a break.

  • Starting from £43.95
Orange blister pack containing 21 round white tablets

Lizinna

Norgestimate/Ethinylestradiol

Very similar pill to Cilest and Cilique and can help to make periods more regular.

  • Starting from £30.95
Silver Gedarel blister pack containing 21 round white tablets labelled with days and arrows

Gedarel

Ethinylestradiol/Desogestrel

Comes as a 'standard' oestrogen dose or a lower dose option. Very similar to Marvelon and Mercilon.

  • Starting from £29.95
Blister strip of Marvelon tablets

Marvelon

Ethinylestradiol/Desogestrel

Pill with a 'regular' oestrogen dose. Comes in a 21 pack. Very similar to Cimizt and Gedarel 30.

  • Starting from £34.95
Blister strip of Ovranette tablets

Ovranette

Ethinylestradiol/Levonorgestrel

Very similar to Microgynon and Levest. Safest category pill that makes menstrual bleeds lighter.

  • Starting from £25.95
Blister strip of Cimizt tablets

Cimizt

Ethinylestradiol/Desogestrel

Regular oestrogen dose pill that helps with PMS symptoms. Similar to Marvelon and Gedarel 30.

  • Starting from £28.95
Blister strip of Mercilon tablets

Mercilon

Ethinylestradiol/Desogestrel

Lower dose version of Marvelon. Good option if you get mild side effects on higher oestrogen pills.

  • Starting from £36.95
Silver Yacella blister pack containing 21 round yellow tablets labelled with days of the week

Yacella

Ethinylestradiol/Drospirenone

Helps with PMS and can make periods more regular. Very similar to Yasmin.

  • Starting from £37.95
Blister strip of Femodene tablets

Femodene

Ethinylestradiol/Gestodene

Standard oestrogen dose. Similar to Millinette and Katya. 21 and 28 pill options available.

  • Starting from £34.95
Brevinor Blister Pack UK

Brevinor

Ethinylestradiol/Norethisterone

Phasic pill that's designed to match your cycle. Very similar to Synphase.

  • Starting from £25.95
Maexeni Blister UK

Maexeni

Ethinylestradiol + levonorgestrel

Very low risk pill that's similar to Microgynon and Levest, and helps with heavy bleeding.

  • Starting from £25.95
Blister strip of Qlaira tablets

Qlaira

Estradiol/Dienogest

Unique 4-phase pill designed to match fluctuating hormone cycles. Comes in 28 pill packs.

  • Starting from £59.95
Silver Lucette blister pack containing 21 round white tablets marked with arrows

Lucette

Ethinylestradiol/Drospirenone

Very similar to Yasmin. Can help with PMS and making your periods more regular.

  • Starting from £39.95
Silver Synphase blister pack containing 12 light blue tablets and 9 white tablets

Synphase

Norethisterone/Ethinylestradiol

Phasic pill that matches changes in your hormone cycle. Very similar to Brevinor and Ovysmen.

  • Starting from £24.95
Blister Strip of TriRegol tablets

TriRegol

Ethinylestradiol/Levonorgestrel

Triphasic pill. Similar to Microgynon, but with phased doses to match changes during your cycle.

  • Starting from £26.95
Blister strip of Logynon tablets

Logynon

Ethinylestradiol/Levonorgestrel

Phased dose pill, similar to TriRegol. Designed to match changes in hormone during your cycle.

  • Starting from £28.95
Bimizza Blister UK

Bimizza

Ethinylestradiol/Desogestrel

Lower dose of oestrogen. Similar to Mercilon and Gedarel 20.

  • Starting from £32.95
Zoely blister UK

Zoely

Estradiol/Nomegestrol

Higher oestrogen dose pill, helps to make periods more regular.

  • Starting from £51.95
Blister strip of Femodene tablets

Femodette

Ethinylestradiol/Gestodene

Lower dose version of Femodene. Comes in a 21 pill pack or a 28 pill pack you take without a break.

  • Starting from £35.95
Blister strip of Millinette tablets

Millinette

Ethinylestradiol/Gestodene

Same hormone mix and dose as Femodene and Marvelon. Lower oestrogen version available.

  • Starting from £29.95
Silver blister pack containing 21 small round blue tablets

Cilique

Norgestimate and ethinyl estradiol

Also known as Cilest. Can help to make your periods more regular.

  • Starting from £30.95
generic

Norimin

Norethisterone/ethinylestradiol

21-day pill with a seven day break, similar to Norinyl-1. Contains a low dose of oestrogen.

  • Starting from £36.95
Pink blister pack containing 21 round white tablets

Sunya

Ethinylestradiol/Gestodene

Lower dose version of Katya. Less oestrogen, better if you've had side effects on higher doses.

  • Starting from £32.95
Silvery blue Katya blister pack containing 21 round white tablets

Katya

Ethinylestradiol/Gestodene

Standard oestrogen dose pill that's very similar to Femodene and Millinette.

  • Starting from £32.95
Silver blister pack containing 21 round white tablets

Norinyl-1

Norethisterone/Mestranol

Contains a different type of oestrogen to most other pills but gives the same protection level.

  • Starting from £25.95
Akizza blister online

Akizza

Ethinylestradiol/Gestodene

Comes as a regular or low oestrogen dose. Helps with PMS.

The contraceptive ring

The contraceptive ring, also known as the vaginal ring, is inserted into the vagina and remains in place for three weeks, which is then followed by a ring-free week. The contraceptive ring requires replacement every three weeks, compared to weekly with the patch or daily with the pill. But on the flip side, it can be uncomfortable to insert and shouldn’t be used after the age of 50.

Compared to combined oral contraceptives, individuals using the contraceptive ring reported fewer accounts of nausea, irritability and depression, but did have a higher frequency of vaginitis (vaginal infection) and genital itching.

A potential benefit is the vaginal lubrication you get from the localised oestrogen. Many menopausal women suffer from vulvovaginal atrophy, a condition that causes symptoms, like vaginal dryness, irritation, and soreness. In a study, up to 98% of individuals who used the contraceptive ring felt their symptoms improved significantly.

Contraception: Here's what we've got.

Individual NuvaRing

Nuvaring

Ethinylestradiol/Etonogestrel

Small, flexible ring. Sits in the vagina and works like the pill. Only needs changing once a month.

  • Starting from £71.95

Non-hormonal methods

There are three main options for non-hormonal methods of contraception, including condoms, copper IUD, and sterilisation. These methods are good for perimenopausal women who want effective protection without the additional hormones. They can also be suitable for women who have or are at risk of breast cancer.

Condoms

Barrier methods, such as male and female condoms, are a reliable form of contraception for menopausal women. They’re effective at preventing pregnancy and can offer protection against sexually transmitted infections (STIs). However, it’s important to note that although they are 98% effective at preventing pregnancy, their effectiveness can be reduced by user errors and accidental damage.

Copper coil

The copper coil, or intrauterine device (IUD) is an effective method of contraception that works by creating a toxic environment unsuitable for the sperm to survive in, preventing the fertilisation of an egg.

It’s a LARC that lasts approximately 10 years, which can be a convenient option for women who don’t wish to be concerned about contraception for a long time. It’s also one of the most effective non-hormonal methods, with a very low failure rate.

But because of the lack of hormones, it can’t help manage your menopausal symptoms. You might also experience heavier bleeding and increased cramping, which can worsen your menopausal symptoms. Lastly, there’s a small risk of dislocation, which could cause it to lose its contraceptive effect.

Sterilisation

Sterilisation is a permanent method of contraception, making it a favourable method for women who no longer wish to have children. There are different procedures available, such as tubal ligation, the closing of your fallopian tubes, and hysterectomy, the removal of your womb, remember, sterilisation is one of the few contraceptive options available for men, it’s more reliable and less invasive too. Because of the different procedures, you will have different benefits and disadvantages.

If you have a hysterectomy, it can eliminate menstrual periods, meaning you won’t ever experience heavy bleeding, painful cramps, or other menstrual symptoms. This is because, without a womb, you won’t have a menstrual or ovulatory cycle. But you can still encounter hormonal changes, that could result in menopausal symptoms, such as hot flushes, and vaginal dryness.

However, tubal ligation won’t have the same benefits as a hysterectomy as your hormones won’t be affected. You’ll still experience bleeding and menstrual symptoms, although some women have noticed lighter and less painful periods. Nevertheless, it is a method that’s over 99% effective, so you can comfortably have sexual intercourse without worrying about the risk of pregnancy. And if you change your mind later on, it can be a reversible process so you could become fertile again.

What are the benefits of using contraception in your 50s?

Using contraception in your 50s can have benefits beyond preventing pregnancy. The most important benefit is that it can help ease your transition into menopause by managing your menopausal symptoms, like night sweats, irregular bleeding and cramps. Both hormonal and non-hormonal methods of contraception can provide this benefit, but hormonal methods are more effective.

Furthermore, if you take hormonal contraceptives, they can help regulate your hormone levels and prevent extreme hormonal fluctuations. This can be beneficial in regulating your period cycle and lightening your periods. Additionally, it can reduce vasomotor symptoms, such as hot flashes and night sweats.

Using certain types of contraceptives can also decrease your risk of some health conditions. For instance, the progesterone-only pill can reduce the risk of endometrial and breast cancer.

Can HRT be used as contraception?

No, hormone replacement therapy (HRT) can’t be used as a contraception even if the same hormones are used. This is because the hormone concentration in HRT is lower than that of contraceptives, so it won’t have much of a contraceptive effect. This was found in a study that showed only 40% of HRT users had inhibited ovulation, meaning there was a 60% chance of getting pregnant. The only HRT that has a contraceptive effect is the Mirena coil. Although it works primarily as a contraceptive, it also works systematically to help menopausal symptoms.

At what age can I stop using contraception?

You can stop contraception at any time, but if you are sexually active and don’t want to get pregnant then it’s recommended to wait until you have reached menopause, typically around the age of 51.

If you’re under 50, you can stop using contraceptives without the risk of pregnancy two years after your last period. If you’re over 50, you can stop using contraceptives one year after your last period.

However, if you’re over 50 and you haven’t reached menopause yet, it’s recommended to continue using contraceptives. Although fertility declines with age, there’s still a possibility of becoming pregnant.

Your contraceptive choices at 50 do become limited, but your doctor will discuss the most suitable options for you based on your medical history and risks. Listed below are some contraceptive guidelines for women over the age of 50:

Combined contraceptives should be stopped over the age of 50. You will be advised to switch to progesterone-only methods or non-hormonal methods.
Contraceptive injection should be stopped, your doctor will recommend a suitable alternative.
Progesterone-only methods can be continued until you’re 55. At this age, you’ll usually have a natural loss of fertility, but your doctor might confirm you’re infertile with a test.

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When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

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