2 hormones, 1 pill for 99% protection.

Yacella is a combined contraceptive pill that contains two hormones, drospirenone and ethinyl estradiol.
Tell us about your health, and get recommendations for treatment from our experts. Choose your pill, and order Yacella online on a delivery schedule that works best for you.
Yacella contains two hormones which are very similar to hormones to the ones your body produces to control the menstrual cycle. It’s the “combination” of these that makes it a “combined” contraceptive pill.
Hormones that the body produces naturally rise and fall, controlling the menstrual cycle so that the usual things that need to happen for you to get pregnant take place, like ovulation. Yacella stops these natural fluctuations and so prevents pregnancy, changing the hormonal balance in your body.
The combined pill is a popular choice because it’s completely reversible. You can stop taking it anytime if you decide you want to start a family.
To make sure it’s safe to use, contraceptive pills like Yacella are tested before they are released to the public. It’s quite common for the pill to cause some milder side effects when you first start taking it, but these normally go away on their own after a short time.
If they persist, our clinician may be able to find you a better solution, which might include tweaking your dose or suggesting another type of pill, such as the mini pill.
There are four other pills that are ‘bioequivalent‘. This means they have exactly the same hormones in them, in exactly the same amounts. These are called Lucette, Yasmin, Dretine and Yiznell. So the pills should work in the same way, even if they look different, come in different packaging and are priced differently.
There’s also a pill called Eloine. It’s like Yacella, but has slightly less oestrogen hormone in it. So if you get side effects on Yacella like headaches or nausea, you might be better trying Eloine.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Yacella instructions are straightforward and easy to follow. Once you get into the habit of taking it, it becomes second nature.
Each strip of Yacella contains the 21 pills you need to take for each 28-day cycle. Above each pill are the days of the week, which helps you to keep track of what’s been taken.
Take one pill a day for 21 days, at the same time every day.
Once you reach the end of your strip, you should take a seven day break, during which you will likely experience a withdrawal bleed. On the eighth day, start the next strip of 21 pills.
It can be taken with or without food and should be swallowed whole with water.
If you have not taken a hormonal contraceptive the previous month, you should take the first Yacella tablet at the beginning of your cycle. This is the first day of bleeding on your period. This will ensure that you remain fully protected against pregnancy from the outset.
If you take Yacella on another day in your cycle, you’ll need to use a barrier contraceptive, such as a condom, for seven days.
If you have taken a hormonal contraceptive up until the day before you start using Yacella, simply start the 21 pill strip and complete the course, even if this extends the number of days you are taking a contraceptive. At the end of the cycle, take the seven day break as usual.
If you have taken the mini pill, or any progesterone only contraceptive, up until the first day of using Yacella, you should start the strip of 21 pills the day after finishing your previous method. When switching from a progesterone only pill to a combined pill, you’ll need to use a barrier contraceptive for the first seven days.
If you miss a Yacella pill, you should check the leaflet that comes with your pill for advice on what to do.
It’s better to take the pill every day at the same time. But if you’re a little late taking it (less than 12 hours) your protection won’t be reduced. Just take the pill when you remember and the next at the normal time.
Beyond 12 hours, it counts as a missed pill and if you miss one or more pills, take the most recent forgotten pill as soon as you remember and the next one at the usual time. This might mean taking two pills on the same day.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Oral Contraceptive Pills. Stat Pearls. U.S.A. NCBI
Weight and Body Composition Changes During Oral Contraceptive Use in Obese and Normal Weight Women. Journal of Women’s Health. U.S.A. NCBI.
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63 Tablets | £29.95 |
126 Tablets | £44.95 Save £14.95 |
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63 Tablets | £32.95 |
126 Tablets | £49.95 Save £15.95 |
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63 Tablets | £32.95 |
126 Tablets | £47.95 Save £17.95 |
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63 Tablets | £26.95 |
126 Tablets | £41.95 Save £11.95 |
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63 Tablets | £39.95 |
126 Tablets | £63.95 Save £15.95 |
252 Tablets | £109.95 Save £49.85 |
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63 Tablets | £34.95 |
126 Tablets | £57.95 Save £11.95 |
252 Tablets | £91.95 Save £47.85 |
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63 Tablets | £27.95 |
126 Tablets | £43.95 Save £11.95 |
252 Tablets | £78.95 Save £32.85 |
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84 Tablets | £27.95 |
168 Tablets | £43.95 Save £11.95 |
336 Tablets | £78.95 Save £32.85 |
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63 Tablets | £25.95 |
126 Tablets | £41.95 Save £9.95 |
252 Tablets | £66.95 Save £36.85 |
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63 Tablets | £41.95 |
126 Tablets | £61.95 Save £21.95 |
252 Tablets | £98.95 Save £68.85 |
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Combined pills: Here are some other options.
Standard oestrogen dose. Similar to Millinette and Katya. 21 and 28 pill options available.
Comes as a 'standard' oestrogen dose or a lower dose option. Very similar to Marvelon and Mercilon.
Standard oestrogen dose pill that's very similar to Femodene and Millinette.
Safest category pill, helps with heavy menstrual bleeding. Very similar to Rigevidon and Microgynon.
Very similar to Yasmin. Can help with PMS and making your periods more regular.
Pill with a 'regular' oestrogen dose. Comes in a 21 pack. Very similar to Cimizt and Gedarel 30.
Safest category pill that reduces heavy bleeding. Same hormone mix as Levest and Rigevidon.
Very similar to Microgynon and Levest. Safest category pill that helps with heavy menstrual bleeds.
Well known pill that reduces PMS symptoms and can help to make your periods more regular.
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