Morning sickness

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Morning sickness

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Rated

4.5

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Rated

4.5

Summary

Nausea and vomiting in the morning is common in early pregnancy, and can be severe.
We don’t know what causes morning sickness, but hormonal changes are thought to be the culprit.
OTC treatment and lifestyle changes can help. Prescription medicine is available for severe cases.

Morning sickness: essential info
Causes and symptoms
What are my options?
FAQ

Reviewed on February 14, 2026. by

Dr Daniel Atkinson

GP Clinical Lead

GMC (No. 4624794)

Next review due on February 14, 2029

Last updated on January 28, 2026

Find the morning sickness treatment that’s best for you.

We’ve got a range of options, and our clinicians can help you find the one that’s best for your body and your budget.

Prochlorperazine

In stock

Treat morning sickness, enjoy a healthy pregnancy. Effective anti-nausea tablets delivered to you.

Starting from £54.95

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Xonvea

doxylamine succinate + pyridoxine hydrochloride

Rated

(4)

In stock

The only pill made for morning sickness. Easy tablet for a better pregnancy.

Starting from £86.95

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Cyclizine

Cyclizine hydrochloride

In stock

An effective tablet that can relieve morning sickness within 2 hours.

Starting from £44.95

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Metoclopramide

In stock

Tablet available in three different strengths that works in the brain to reduce nausea.

Starting from £38.95

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What is morning sickness?

Morning sickness is a condition during pregnancy that causes nausea and vomiting. It usually begins around the sixth week of pregnancy, and continues until about the second trimester.

Despite its name, morning sickness can occur any time of the day or night. It’s most severe during the first trimester, but it isn’t always confined to that time. Many women can even have it all day long, and throughout the duration of their pregnancy.

Some women have very mild symptoms, while others can become more ill. Whilst many women can get relief from over the counter remedies, the most serious cases of morning sickness can require prescription treatments.

How common is morning sickness?

Morning sickness is a very common condition during pregnancy. About 70% of pregnant women will experience some level of morning sickness.^[1] Some women have it so severely that it progresses to a condition called hyperemesis gravidarum.

A pregnant woman with hyperemesis gravidarum may become dangerously dehydrated, or lose more than 5% of her body weight prior to pregnancy.^[2] In severe morning sickness cases, and for women suffering from hyperemesis gravidarum, treatment will often be necessary.

Treated trusted sources:

Cleveland Clinic. (2017). Morning Sickness, Nausea & Vomiting of Pregnancy.
Mayo Clinic. (2020). Morning sickness – Symptoms and causes.

This page was written by The Treated Content Team.

This page was medically reviewed by Dr Daniel Atkinson on February 14, 2026. Next review due on February 14, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

What causes morning sickness?

The causes of morning sickness aren’t fully understood, but a widely accepted theory is that it’s the increased hormones during the first trimester that cause the nausea and vomiting.^[1] Another potential cause of morning sickness is the hypersensitivity to smells that can happen during pregnancy.

What are the symptoms of morning sickness?

The symptoms of morning sickness are often consistent between different people. It usually involves nausea and vomiting that can be triggered by unpleasant smells, hunger, and increased saliva production caused by pregnancy. Some women can also experience morning sickness onset after eating certain foods that are spicy or sweet.

Can morning sickness lead to other problems?

Morning sickness doesn’t usually have any long term effects. It’s uncomfortable and inconvenient, but doesn’t harm the pregnant mother or unborn fetus in most cases, unless it progresses to hyperemesis gravidarum.

When you have hyperemesis gravidarum, the accompanying dehydration and weight loss can affect the health of both you and your baby. In the most severe cases, it can lead to hospitalisation. If your morning sickness or hyperemesis gravidarum is preventing you from keeping food or water down, talk to your clinician. There might be a treatment that can help you to control your symptoms.

Treated trusted sources:

National Health Service (NHS). (2020). Vomiting and morning sickness.

This page was written by The Treated Content Team.

This page was medically reviewed by Dr Daniel Atkinson on February 14, 2026. Next review due on February 14, 2029.

How we source info.

What medications are there for morning sickness?

There are lots of available medications that can help you with the symptoms of morning sickness, and they can work in different ways. Some of them are marketed specifically for pregnant women with morning sickness, while others are general nausea medications that are prescribed for different conditions.

Doxylamine/Pyridoxine (Xonvea in the UK) is a prescription medication that’s marketed specifically for morning sickness. This combination medication includes two active ingredients: doxylamine succinate and pyridoxine hydrochloride. Other off-label treatment options include Cyclizine, Metoclopramide, and Prochlorperazine. Off-label simply means that these medications’ use for treating morning sickness isn’t specified in the license, but they’re commonly used for this purpose in clinical practice, so they’re considered safe.

Is there a ‘best’ treatment for morning sickness?

The best morning sickness treatment for you will depend on your needs. Your health history will help our clinician to determine which medications might be safest for you and your baby.

If you’re not sure which treatment option could be best for you, our experts can help you decide once you’ve talked to us about your health. Based on your medical history, symptoms and personal preferences, your clinician can help to point you in the right direction.

Does morning sickness always need treatment?

You don’t always need to take prescribed medications to help with your morning sickness symptoms. Sometimes your symptoms can be helped by trying natural foods, some supplements or by adjusting your diet.

Some studies have suggested that ginger has the potential to provide relief from morning sickness, but research is still quite limited.^[1]

Most women will see their morning sickness symptoms resolve between weeks 16-20.^[2] If morning sickness symptoms go away fully during the second trimester, you shouldn’t need to continue any treatments or home remedies. Mild morning sickness symptoms might not require any intervention if they’re bearable, so you can choose whether or not you’d like to use any treatments based on your own comfort and needs.

Treated trusted sources:

Ernst, E. and Pittler, M.H. (2000). Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. British Journal of Anaesthesia, 84(3), pp.367–371.
Lacroix, R., Eason, E. and Melzack, R. (2000). Nausea and vomiting during pregnancy: A prospective study of its frequency, intensity, and patterns of change. American Journal of Obstetrics and Gynecology, 182(4), pp.931–937.

How we source info.

FAQ: Morning sickness

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

Can you get side effects from morning sickness treatment?

Answer:

You might experience side effects from your morning sickness medication, and they’ll usually vary - depending on the treatment that you’re using. Xonvea is the primary treatment option that’s marketed specifically for morning sickness. People who take Doxylamine/Pyridoxine might experience fatigue, dizziness and dry mouth.

Other medications like Cyclizine, Metaclopromide, and Prochlorperazine that are used to treat nausea and vomiting for a variety of conditions, including pregnancy, have a range of potential side effects. Depending on which one you’re taking, you could experience:

Loss of appetite

Headaches

Rashes

Insomnia

Diarrhea

Constipation

Tremors

Mood changes

Weakness

Changes in blood pressure

Increased prolactin

Blood clots

Seizures

For more specific advice on morning sickness treatment side effects, you can visit our individual product pages, or refer to your patient information leaflet.

Is morning sickness treatment safe?

Answer:

Medications to treat the symptoms of morning sickness are generally safe. Some people might prefer a medication like Doxylamine/Pyridoxine, because it’s formulated specifically for pregnant women. Other medications are also safe, but are more frequently used to treat nausea and vomiting caused by something else, like motion sickness or chemotherapy.

Do you need a prescription for morning sickness treatments?

Answer:

Most morning sickness treatments will require a prescription so that your clinician can monitor your condition. This is especially true for medications for pregnant women, because of the sensitive nature of pregnancy and the increased risk of health complications.

If you’re considering morning sickness treatments, talk to your clinician about the different options. They can determine which is most appropriate for you based on your medical history and personal preferences.

Does morning sickness treatment always work?

Answer:

Morning sickness treatments are effective, but results can vary. They can be highly effective for some women, but might not work as well for others.

Doxylamine/Pyridoxine has proven to be particularly effective for treating the symptoms of morning sickness. Pregnant women reported 68% reduced nausea while taking Xonvea and doctors rated this medication as 78% effective. Nearly 50% of women reported that they hadn’t vomited in five days or more while taking Xonvea.^[1]

Other nausea medications can also be effective. Combining these treatments with lifestyle changes and home remedies could increase relief from symptoms. Discuss the options with our clinician to determine which treatments could be best for you.

Treated trusted sources:

NICE. (2021). Doxylamine/pyridoxine (Xonvea) for treating nausea and vomiting of pregnancy.

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Dr Daniel Atkinson

GP Clinical Lead

Registered with GMC (No. 4624794)

Ms Sanjeda Chowdhury

Superintendent Pharmacist + Independent Prescriber

Registered with GPhC (No. 2202465)

Mr Craig Marsh

Independent Prescriber

Registered with GPhC (No. 2070724)

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