Trusted Shops is a company that validates online merchants and offers buyer protection services.
They audit the processes companies use to trade online and provide a 'TrustMark' to those who meet their criteria of being price transparent, and offering quality customer service and data security.
Price checker
25mcg/24hr
37.5mcg/24hr
50mcg/24hr
75mcg/24hr
100mcg/24hr
£39.95
8 Patches£39.95
24 Patches£77.95Save £41.90
Prices include:
Express shipping
24 hour shipping by secure courier.
Consultation + Access to our clinicians
Ask our experts anything you like, any time you want.
Total
£39.95
Save £0.00 each order
Reviewed on Aug 27, 2024. byDr Daniel AtkinsonGP Clinical LeadRegistered with GMC (No. 4624794)Next review due on August 29, 2027.
Last updated on Aug 27, 2024.
Product info
Estradot is a HRT patch that treats moderate to severe menopause symptoms.
You wear the patch daily, replacing it twice each week.
Estradot works by replacing falling oestrogen levels in your body.
Price checker
25mcg/24hr
37.5mcg/24hr
50mcg/24hr
75mcg/24hr
100mcg/24hr
£39.95
8 Patches£39.95
24 Patches£77.95Save £41.90
Prices include:
Express shipping
24 hour shipping by secure courier.
Consultation + Access to our clinicians
Ask our experts anything you like, any time you want.
Estradot is a HRT medication, or more specifically, a continuous form of HRT. That means it’s a patch that you wear every day (replacing the patch with a new one twice a week), so that the hormone in it is released into the body continuously.
Estradot is just one brand of one type of HRT, with various dosages available. This allows treatments for every phase of the menopause, as well as different strengths of medication that are prescribed depending on severity of your symptoms.
In other words, there’s a treatment for almost everyone going through the menopause.
What is Estradot prescribed to treat?
Estradot is prescribed to control hormone levels when you’re going through the postmenopause. The menopause is a time of life when your hormones begin to fluctuate, signalling the end of menstruation and fertility. It’s a natural process but it can have a significant effect on your life and wellbeing.
The postmenopause describes the time after your period has stopped, while the perimenopause describes symptoms experienced while you still have bleeding.
How does Estradot work?
Menopause symptoms are caused by a drop in the hormone oestrogen. This causes symptoms such as night sweats, hot flushing and brain fog. Estradot contains estradiol hemihydrate, a synthetic version of oestrogen. The increase in oestrogen helps ease the symptoms, making them more manageable.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr Daniel Atkinson on August 29, 2024. Next review due on August 29, 2027.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
EstradotEstradiol
How to apply Estradot
Tear open the patch and peel off one side of the protective backing. Without touching the sticky side, apply half of the patch on your lower abdomen. Fold the patch and remove the other half of the backing. Press the patch firmly on your skin and hold it down for about 10 seconds.
For detailed instructions, check the patient leaflet.
What to do when you start using Estradot
Instructions at the start of a treatment for Estradot will depend on a number of things. If you’re:
currently using continuous or combined HRT (containing two hormones), you can start using Estradot whenever you want.
changing from sequential HRT (where progesterone is taken for about 12 days), you should start Estradot after completing your previous cycle.
If you’re not sure what type of HRT you’ve been using, speak with your clinician, who will be able to advise you.
Where to apply Estradot patches
Estradot patches should be applied to the lower part of your body and never to your breasts. The area of skin should be hairless and should not be placed on an area where you might wear elastic, such as your waist or lower legs. When replacing your patch, you should avoid using the same patch of skin.
After use, fold the patch onto itself (so the sticky side is completely covered) and throw it in the bin. You should never flush your HRT patch down the toilet.
When to change your Estradot patch
Estradot should be replaced two times a week, every three to four days. You should try to stick to the same days each week, for example, every monday and thursday.
For other days, follow the same pattern. For instance: Wednesday – Saturday – Wednesday. You can write the day the patch will be used on with the calendar checklist that comes with Estradot to keep track of your use.
What should I do if you forget to change the patch?
If you forget to change your patch on the scheduled day, simply change it as soon as you remember and go back to the normal schedule after this, no matter how short the time you’ll be using it.
So, for example, if you forget to take the patch on Monday and remember on Wednesday, use the new patch for one day and go back to the Thursday – Monday – Thursday schedule.
This page was written by The Treated Content Team.
This page was medically reviewed by Dr Daniel Atkinson on August 29, 2024. Next review due on August 29, 2027.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
EstradotEstradiol
Estradot isn’t suitable for everyone, and there are some things that you need to be aware of when using it.
Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.
EstradotEstradiol
FAQ: Estradot
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
What are the ingredients in Estradot?
Answer:
The active ingredient in Estradot is the synthetic version of the hormone oestrogen, called estradiol hemihydrate. It’s released slowly into the body over the course of a few days before it needs to be changed.
Women who have had a hysterectomy can use Estradot safely, women who still have their womb should have an additional progesterone, either from a Mirena ‘coil’ or from progesterone gel or tablets which are taken for several days per month. [1]
What Estradot doses are there?
Answer:
There are five doses of Estradot: 25mcg, 50 mcg, 37.5mcg, 75mcg, and 100mcg. Estradot 25mcg or 50mcg are the most commonly prescribed dosages at the beginning of your treatment. Your prescribing clinician will then monitor to see if Estradot 100 or 75 might be needed.
How long does it take Estradot to work?
Answer:
It usually takes a few weeks before you’ll start to feel the benefits of HRT, and up to three months before it becomes fully effective, so a little patience is needed.
During this time, you might feel some side effects as the body gets used to the new hormones. These will likely subside after around six to eight weeks, but if they don’t, speak with our clinician about lowering your dosage or trying a different medication.
What should I do if you forget to change the patch?
Answer:
If you forget to change your patch on the scheduled day, simply change it as soon as you remember and go back to the normal schedule after this, no matter how short the time you’ll be using it.
So, for example, if you forget to take the patch on Monday and remember on Wednesday, use the new patch for one day and go back to the Thursday - Monday - Thursday schedule.
Can I cut the patch in half?
Answer:
You should not cut the patch in half. If you believe the dose you are receiving is too high, you should discuss this with our clinician.
Getting the right amount of hormones in the body can be tricky, but with a little patience, and the right guidance from us, you should be able to get the right treatment for you. No matter how small you think the issue is, we’re always here to help.
Is there a difference between Estradot or Evorel?
Answer:
Estradot and Evorel are two of the most popular oestrogen only HRT treatments, but is there any difference between the two in their effectiveness? In short, no, and the same goes for any other oestrogen only medication.
HRT delivered through the skin (transdermally) using patches or gel is a little safer than tablets from women who have cardiovascular risk factors, such as high blood pressure, heart problems, being overweight or having high cholesterol.
Apart from dosages and the form the treatment comes in (Estradot and Evorel are patches, while Oestrogel is a gel and Zumenon is available as a tablet) the only other difference is branding and price.
Do I need a prescription for Estradot?
Answer:
Yes, our clinician will need to assess and monitor how your symptoms are progressing during treatment. What’s more, oestrogen only HRT, such as Estradot, can present significant health risks for some women while being perfectly safe for others.
Thankfully, there are many treatments available, so our clinical team should be able to find the right option for you.
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Why this page was updated on Aug 27, 2024
Content checked and updated as part of our 3-yearly periodic review, to ensure accuracy and currentness.
Current version (Aug 27, 2024)
Edited by: The Treated Content Team.Medically reviewed by: Dr Daniel Atkinson, GP Clinical Lead
Aug 01, 2022
Published by: The Treated Content Team.Medically reviewed by: Dr Daniel Atkinson, GP Clinical Lead
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
This is healthcare on your terms.
All from the comfort of your device. Get access to what you need, when you need it.
100% online
Ask questions and get expert recommendations, at the touch of a button.
Tailored choices
We'll narrow down some treatments for you to choose from based on your medical profile.
Express delivery
Receive your treatment by secure delivery, in discreet packaging.
Repeats made easy
Set your own delivery schedule and pause or make changes any time you like.
Users find Estradot patches to be effective in managing menopausal symptoms. The patches are consistently described as small, convenient, and easy to apply. A key benefit noted by multiple users is that they adhere well to the skin and do not fall off easily.
I did not know that increasing the dose also increased the price. Too bad.
A
AnoniemVerified user Verified useron May 05, 2026
551
Very satisfied with Treated.com. The entire process is tightly organized, clear intake, quick assessment by a doctor and then fast delivery. Everything feels professional and discreet.
What is particularly striking is the convenience! You can arrange everything online without hassle, but with medical check-ups.
In short: reliable, efficient and user-friendly. Definitely recommended.
A
AnoniemVerified user Verified useron May 05, 2026
551
Treatment plan is good. Medicine is providing help for issue. Service was professional.
C
ChristopherVerified user Verified useron May 03, 2026
551
Very professional!
M
MarkusVerified user Verified useron April 27, 2026
551
I am very satisfied with the effect
G
GünterVerified user Verified useron April 27, 2026
We're making healthcare more about you. Sign up to our newsletter for personalised health articles that make a difference.
Dr Daniel Atkinson
GP Clinical Lead
Dr Daniel oversees all matters clinical at Treated. He supports the rest of our team to make sure everything we’re doing is safe and puts patients first. He also spends a lot of time consulting with patients first hand, so he can see how well things are working and what we can improve. Registered with the GMC (No. 4624794).
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Reviews you can trust
All of our reviews are collected from real patients after their treatment has been delivered.
We publish reviews collected through independent platforms including Reviews.io and Trustpilot.