Estradot
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Reviewed on August 29, 2024. by
Dr Daniel Atkinson
GP Clinical Lead
Registered with GMC (No. 4624794)
Next review due on August 29, 2027.
Dr Daniel Atkinson

Product info

  • Estradot is a HRT patch that treats moderate to severe menopause symptoms.

  • You wear the patch daily, replacing it twice each week.
  • Estradot works by replacing falling oestrogen levels in your body.

Price checker
£39.95
  • Prices include:
    Express shipping

    24 hour shipping by secure courier.

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    £39.95
    Save £0.00 each order
Estradot Estradiol

What is Estradot?

Estradot is a HRT medication, or more specifically, a continuous form of HRT. That means it’s a patch that you wear every day (replacing the patch with a new one twice a week), so that the hormone in it is released into the body continuously. Estradot is just one brand of one type of HRT, with various dosages available. This allows treatments for every phase of the menopause, as well as different strengths of medication that are prescribed depending on severity of your symptoms. In other words, there’s a treatment for almost everyone going through the menopause.

What is Estradot prescribed to treat?

Estradot is prescribed to control hormone levels when you’re going through the postmenopause. The menopause is a time of life when your hormones begin to fluctuate, signalling the end of menstruation and fertility. It’s a natural process but it can have a significant effect on your life and wellbeing. The postmenopause describes the time after your period has stopped, while the perimenopause describes symptoms experienced while you still have bleeding.

How does Estradot work?

Menopause symptoms are caused by a drop in the hormone oestrogen. This causes symptoms such as night sweats, hot flushing and brain fog. Estradot contains estradiol hemihydrate, a synthetic version of oestrogen. The increase in oestrogen helps ease the symptoms, making them more manageable.

Treated trusted sources:

  1. Newson, L.R. (2016). Best practice for HRT: unpicking the evidence. British Journal of General Practice, 66(653), pp.597–598.
treated.com This page was written by The Treated Content Team.
Dr Daniel Atkinson
This page was medically reviewed by Dr Daniel Atkinson on August 29, 2024. Next review due on August 29, 2027.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Estradot Estradiol

How to apply Estradot

Tear open the patch and peel off one side of the protective backing. Without touching the sticky side, apply half of the patch on your lower abdomen. Fold the patch and remove the other half of the backing. Press the patch firmly on your skin and hold it down for about 10 seconds.

For detailed instructions, check the patient leaflet.

What to do when you start using Estradot

Instructions at the start of a treatment for Estradot will depend on a number of things. If you’re:

  • currently using continuous or combined HRT (containing two hormones), you can start using Estradot whenever you want.
  • changing from sequential HRT (where progesterone is taken for about 12 days), you should start Estradot after completing your previous cycle.

If you’re not sure what type of HRT you’ve been using, speak with your clinician, who will be able to advise you.

Where to apply Estradot patches

Estradot patches should be applied to the lower part of your body and never to your breasts. The area of skin should be hairless and should not be placed on an area where you might wear elastic, such as your waist or lower legs. When replacing your patch, you should avoid using the same patch of skin.

After use, fold the patch onto itself (so the sticky side is completely covered) and throw it in the bin. You should never flush your HRT patch down the toilet.

When to change your Estradot patch

Estradot should be replaced two times a week, every three to four days. You should try to stick to the same days each week, for example, every monday and thursday.

For other days, follow the same pattern. For instance: Wednesday – Saturday – Wednesday. You can write the day the patch will be used on with the calendar checklist that comes with Estradot to keep track of your use.

What should I do if you forget to change the patch?

If you forget to change your patch on the scheduled day, simply change it as soon as you remember and go back to the normal schedule after this, no matter how short the time you’ll be using it.

So, for example, if you forget to take the patch on Monday and remember on Wednesday, use the new patch for one day and go back to the Thursday – Monday – Thursday schedule.

treated.com This page was written by The Treated Content Team.
Dr Daniel Atkinson
This page was medically reviewed by Dr Daniel Atkinson on August 29, 2024. Next review due on August 29, 2027.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Estradot Estradiol

Estradot isn’t suitable for everyone, and there are some things that you need to be aware of when using it.

Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.

Estradot Estradiol

FAQ: Estradot

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

What are the ingredients in Estradot?

Answer:
The active ingredient in Estradot is the synthetic version of the hormone oestrogen, called estradiol hemihydrate. It’s released slowly into the body over the course of a few days before it needs to be changed.

Women who have had a hysterectomy can use Estradot safely, women who still have their womb should have an additional progesterone, either from a Mirena ‘coil’ or from progesterone gel or tablets which are taken for several days per month. [1]

What Estradot doses are there?

Answer:
There are five doses of Estradot: 25mcg, 50 mcg, 37.5mcg, 75mcg, and 100mcg. Estradot 25mcg or 50mcg are the most commonly prescribed dosages at the beginning of your treatment. Your prescribing clinician will then monitor to see if Estradot 100 or 75 might be needed.

How long does it take Estradot to work?

Answer:
It usually takes a few weeks before you’ll start to feel the benefits of HRT, and up to three months before it becomes fully effective, so a little patience is needed.

During this time, you might feel some side effects as the body gets used to the new hormones. These will likely subside after around six to eight weeks, but if they don’t, speak with our clinician about lowering your dosage or trying a different medication.

What should I do if you forget to change the patch?

Answer:
If you forget to change your patch on the scheduled day, simply change it as soon as you remember and go back to the normal schedule after this, no matter how short the time you’ll be using it.

So, for example, if you forget to take the patch on Monday and remember on Wednesday, use the new patch for one day and go back to the Thursday - Monday - Thursday schedule.

Can I cut the patch in half?

Answer:
You should not cut the patch in half. If you believe the dose you are receiving is too high, you should discuss this with our clinician.

Getting the right amount of hormones in the body can be tricky, but with a little patience, and the right guidance from us, you should be able to get the right treatment for you. No matter how small you think the issue is, we’re always here to help.

Is there a difference between Estradot or Evorel?

Answer:
Estradot and Evorel are two of the most popular oestrogen only HRT treatments, but is there any difference between the two in their effectiveness? In short, no, and the same goes for any other oestrogen only medication.

HRT delivered through the skin (transdermally) using patches or gel is a little safer than tablets from women who have cardiovascular risk factors, such as high blood pressure, heart problems, being overweight or having high cholesterol.

Apart from dosages and the form the treatment comes in (Estradot and Evorel are patches, while Oestrogel is a gel and Zumenon is available as a tablet) the only other difference is branding and price.

Do I need a prescription for Estradot?

Answer:
Yes, our clinician will need to assess and monitor how your symptoms are progressing during treatment. What’s more, oestrogen only HRT, such as Estradot, can present significant health risks for some women while being perfectly safe for others.

Thankfully, there are many treatments available, so our clinical team should be able to find the right option for you.

Treated trusted sources:

  1. Vinogradova, Y., Coupland, C. and Hippisley-Cox, J. (2020). Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases. BMJ, 371.

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Dr Daniel Atkinson

GP Clinical Lead
Dr Daniel Atkinson

Registered with GMC (No. 4624794)

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Registered with GPhC (No. 2070724)

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Registered with GPhC (No. 2202465)

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Similar but different

Menopause (HRT): Here are our other options.

Blister strip of Elleste Solo tablets
Elleste Solo Estradiol

Oestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.

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Individual Evorel Conti patch
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Sachet containing individual Evorel Sequi patch
Evorel Sequi Estradiol/Norethisterone

Sequential dose patch. Use to manage menopause symptoms if you still have periods.

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Blister strip of Femoston tablets
Femoston Estradiol/Dydrogesterone

Comes as a continuous or sequential tablet, depending on whether you're still having periods.

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Generic
Gina Estradiol

Oestrogen-only HRT to tackle vaginal menopause symptoms.

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Dash of Duac Gel
Oestrogel Estradiol

HRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.

  • Works in N/A
  • Lasts for 24 hours
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£44.95
See this option
Generic
Progynova Estradiol

Oestrogen only tablet or patch for women who've had a hysterectomy, or used alongside a progesterone in combined HRT.

  • Works in N/A
  • Lasts for 24 hours
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£55.95
See this option
tibolone
Tibolone Tibolone

Generic version of Livial. Hormone-free HRT that can improve mood and libido.

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£33.95
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Silver blister pack containing 15 round tablets
Utrogestan Micronised progesterone

The natural progesterone treatment. Taken alongside oestrogen to relieve symptoms of menopause.

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£37.95
See this option

Here’s what you had to say

  • Product reviews
  • Service reviews
Estradot
4.0

Average rating based on 20 reviews.

Our verification process
551

Does the business

Good product, does the business and doesn't fall off like some of the others.

D
551

Convenient application and reliable srvice

Patch is well tolerated and easy to apply

A
551

Good customer service by Treated

Can’t say if Estradot is working after a week but I can say they are at least sticking well - customer service and the whole process from treated has been exceptional - if only the nhs worked like this,

A
551

Easy and convenient

Easy and convenient

C
551

Fantastic & Quick service

I’ve used Treated twice for obtaining my HRT when there has been a national shortage, and been able to get it from them both times. Perfect service. Would use again if needed to.

A
Read all reviews  

Read more about Estradot

Further reading

Take a look at our helpful health guides related to menopause (hrt).

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