- Biguanides - metformin, the most commonly prescribed first-line treatment for type-2 diabetes, comes under this category
- Sulfonylureas - these work by increasing the amount of insulin secreted by the pancreas. You might be prescribed a sulfonylurea instead of metformin if it isn’t suitable for you
- DPP-4 inhibitors - these work by blocking the break-down of hormones which stimulate insulin secretion
- GLP-1 agonists - these treatments are often injected, and they increase your levels of incretins - the hormones that help your pancreas produce more insulin
- SGLT-2 inhibitors - these work by increasing the amount of glucose that gets excreted in your urine
Komboglyze contains two of these different types of treatments - metformin (a biguanide) and saxagliptin, which is a DPP-4 inhibitor. You can get different treatments which contain just one of these types of medicines (monotherapy) or different combinations of these types of medicines.