Hyperpigmentation
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Summary

  • Hyperpigmentation is a skin condition characterised by uneven patches of dark skin.
  • It might be caused by excess melanin, exposure to sun, or hormonal changes.
  • Treatments include off-label topical creams containing acids that can help lighten darkened skin patches.
Reviewed on July 06, 2026. by
Dr Alexandra Cristina Cowell
Writer & Clinical Content Reviewer
Registered with GPhC (No. 2241935)
Next review due on July 06, 2029
Dr Alexandra Cristina Cowell

Last updated on July 06, 2026

Find the Hyperpigmentation treatment that’s best for you.

We’ve got a range of options, and our clinicians can help you find the one that’s best for your body and your budget.

CeraVe SA Smoothing Cream

Salicylic acid

CeraVe SA Smoothing Cream
In stock

A 3-in-1 treatment that softens, exfoliates and moisturises your skin.

Starting from £59.95

Eucerin

Urea

Creme
In stock

Topical cream that hydrates your skin. Apply twice a day to moisturise or reduce hyperpigmentation.

Starting from £44.95

Tretinoin + Niacinamide

Tretinoin + Niacinamide

Tretinoin + Niacinamide
Out of stock

Topical treatment to help fade hyperpigmentation and melasma.

Starting from £99.95

Tretinoin + Niacinamide + Hydroquinone

Tretinoin + Niacinamide + Hydroquinone

Tretinoin + Niacinamide + Hydroquinone
Out of stock

Triple combination treatment to treat hyperpigmentation and melasma.

Starting from £99.95

Skinoren Cream

Azelaic acid

Creme
Out of stock

Off-label topical cream. Can improve skin pigmentation in 6 months.

Starting from £30.95

Tretinoin

Tretinoin

Creme

Off-label topical cream or capsule for lightening skin pigmentation. Contains a retinoid.

Finacea

Azelaic acid

Dash of Duac Gel
Out of stock

Powerful gel that stops inflammation, gets rid of bacteria and treats hyperpigmentation.

Starting from £39.95

Hydroquinone cream

Hydroquinone

Creme
Out of stock

Prescription-strength topical treatment for dark skin areas. Can be used on the face.

Starting from £35.95

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Meet the team
Dr-Daniel-Atkinson

Dr Daniel Atkinson

GP Clinical Lead

Registered with GMC (No. 4624794)

Ms-Sanjeda

Ms Sanjeda Chowdhury

Superintendent Pharmacist + Independent Prescriber

Registered with GPhC (No. 2202465)

Mr-Craig

Mr Craig Marsh

Independent Prescriber

Registered with GPhC (No. 2070724)

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