Fybogel Mebeverine

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Reviewed on June 19, 2026. by Ms Sanjeda Chowdhury Superintendent Pharmacist + Independent Prescriber Registered with GPhC (No. 2202465) Next review due on Jun 19, 2029.

Last updated on June 19, 2026.

Product info

Fybogel Mebeverine is a treatment for IBS symptoms.
It relieves both constipation and abdominal pain associated with IBS.
It can take up to 24 hours to see the full effects.

Price checker

Prices include:

Express shipping
24 hour shipping by secure courier.
Consultation + Access to our clinicians
Ask our experts anything you like, any time you want.
Total
£85.95

Save £0.00 each order

Fybogel Mebeverine: essential info
Fybogel Mebeverine: instructions
Important stuff you need to know
FAQ

What is Fybogel Mebeverine?

Fybogel Mebeverine is a treatment that eases the symptoms of IBS. It contains two active ingredients: ispaghula husk and mebeverine hydrochloride. Ispaghula husk is derived from a plant that is naturally high in fibre. This makes it a laxative and is often used to treat constipation.^[1]

The second active ingredient is mebeverine hydrochloride, which is a type of antispasmodic. This means it prevents spasms from occurring. ^[3]Together, they treat the symptoms of IBS.

Irritable bowel syndrome (IBS) is a common condition that affects your gastrointestinal system. This includes the mouth, stomach, intestines and more. Common symptoms include bloating, diarrhoea, constipation and pain in the lower abdomen. ^[2]
Although IBS is quite prevalent, there’s no cure. For most people, it’s a long-term condition so taking medication such as Fybogel Mebeverine can help relieve some of the symptoms.

How does Fybogel Mebeverine work?

IBS is commonly associated with discomfort in the lower abdomen. This occurs as a result of the intestines squeezing or tightening. This is known as a spasm. People with IBS may also have a change in stool consistency (either loose or hard) or an increase or decrease in stool frequency. ^[3]

Fybogel Mebeverine works by treating both of these problems. Mebeverine hydrochloride relaxes the muscles in the intestines, thereby preventing spasms from occurring. ^[1]
This prevents pain in the lower abdomen. Ispaghula husk traps water in the intestine. This trapped water combines with any stools making them softer and easier to pass. ^[2]
The increased water in the stools can also increase stool frequency in treating constipation. Spasms linked to IBS can also be relieved by defecation, which is why a laxative like ispaghula husk will help.

The combination of active ingredients used in Fybogel Mebeverine works to prevent spasms in the gut and helps maintain constant bowel movements, helping to treat the symptoms of IBS.

Who can take Fybogel Mebeverine?

Most adults and children over the age of 12 can take Fybogel Mebeverine. However, if you have any of the following, do not take it:

Blocked bowel movements.
Muscle weakness or decreased bowel activity.
Difficulty when swallowing or any throat problems.
Severe constipation or passed blood from the bowel.
A sudden change in bowel habits that has lasted for more than 2 weeks.

Treated trusted sources:

Jalanka, J., et al. (2019). The Effect of Psyllium Husk on Intestinal Microbiota in Constipated Patients and Healthy Controls. International Journal of Molecular Sciences, 20(2)
Daniluk, J., et al (2022). The Efficacy of Mebeverine in the Treatment of Irritable Bowel Syndrome—A Systematic Review. Journal of Clinical Medicine, 11(4)
Saha, L. (2014). Irritable bowel syndrome: Pathogenesis, diagnosis, treatment, and evidence-based medicine. World Journal of Gastroenterology : WJG, 20(22), 6759-6773.

This page was written by The Treated Content Team.

This page was medically reviewed by Ms Sanjeda Chowdhury on June 19, 2026. Next review due on June 19, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

FAQ: Fybogel Mebeverine

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

What are the side effects of Fybogel Mebeverine?

Answer:

Fybogel Mebeverine can cause side effects that can affect some people. Some side effects linked to the use of Fybogel Mebeverine include:

An allergic reaction - such as: hives, swollen face, or rashes. If you experience an allergic reaction, stop taking it immediately and seek immediate medical attention.

Bloating and flatulence during the first couple of days. But usually, once your body adjusts, this should reduce.

Difficulty swallowing and blockage of the bowels. This may increase or occur, especially if you take the treatment with an insufficient amount of water.

What is the difference between Fybogel Mebeverine and Fybogel?

Answer:

Fybogel Mebeverine and Fybogel are two different drugs. Fybogel Mebeverine contains two active ingredients ispaghula husk and mebeverine hydrochloride. This is commonly used to treat IBS. Whereas, Fybogel contains only Ispaghula husk and is used to treat constipation.

How does Fybogel Mebeverine compare to other drugs?

Answer:

Colofac and Buscopan are two other treatments for IBS. Colofac contains the active ingredient mebeverine hydrochloride, which is the same as one of the ingredients used in Fybogel Mebeverine. ^[1] Buscopan is another medicine used to treat the symptoms of IBS and contains the active ingredient hyoscine butylbromide. ^[2] This is another antispasmodic like mebeverine. It relaxes the muscles in your stomach preventing stomach cramps.

Which one you choose depends on your symptoms. If you have stomach cramps, you may want Buscopan. But if you have constipation and spasms, Fybogel Mebeverine may be the better option for you.

When can’t I take Fybogel Mebeverine?

Answer:

Don’t take Fybogel Mebeverine if you are pregnant or breastfeeding.

You should avoid taking Fybogel Mebeverine for 30 to 60 minutes before or after taking insulin and after taking medication for thyroid problems. If you need more info on this, just drop a message to our clinicians.