The once weekly tablet to prevent malaria.

Lariam only needs to be taken once a week to provide protection against malaria in some of the world’s most high risk areas.
Order Lariam online with us and get effective malaria protection when you travel.
Lariam tablets are used to prevent malaria, and contain the active ingredient mefloquine. They’re usually recommended to people travelling to certain locations in South America, central and sub-saharan Africa and south-east Asia that are considered high risk.
Lariam isn’t normally prescribed for travel to low or moderate-risk countries, but it could be advised if other antimalarial medicines - like Malarone or Doxycycline - aren’t suitable for you. Lariam is also recommended if you’re travelling to an area where there’s malaria that’s difficult to treat.
Lariam is taken before, during and after you travel to a high-risk area. It’s taken once a week, starting ten days before departure. You’ll then continue to take it once a week, on the same day, for the duration of your trip, and every week for another four weeks after you leave.
Like all medicines, Lariam can cause side effects. There’s a slightly higher chance of feeling side effects from Lariam compared to Malarone, so it’s usually only prescribed if Malarone isn’t suitable for you.
In 2019 there were an estimated 229 million cases of malaria worldwide . Malaria is a life-threatening disease caused by the plasmodium parasite, which is carried by mosquitoes. Malaria is passed to humans when a mosquito carrying the parasite bites and breaks the skin.
Symptoms of malaria include fever, vomiting and headaches. Symptoms usually appear between 7 to 18 days after you’re infected with malaria, but in some cases it can take up to a year for you to notice them.
Mefloquine, the active ingredient in Lariam, stops plasmodium parasites in the body from multiplying. It does this by preventing the creation of an enzyme the parasite needs in order to spread throughout your body. Once the parasite is weakened, your immune system can kill it off.
Lariam comes in a single dosage: 250mg. It’s suitable for adults and children weighing over 45kg.
One tablet is taken per week, starting ten days before you depart for a high risk area. Then one tablet is taken for each week that you’re in the high risk area. After you’ve left the high-risk area, you’ll take a tablet a week for a further four weeks. In certain cases, such as if you’re taking other medication, you might want to start taking Lariam two to three weeks before you travel. This will be to make sure that the combination of the drugs doesn’t give you any unpleasant effects.
It’s possible for small children to take Lariam, but the dose will need to be altered (depending on the child’s weight).
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
It’s important to take Lariam before, during and after visiting a high risk area. You should always complete the full course of Lariam that you’re prescribed to ensure that you’re protected from malaria.
You should always take Lariam as directed by our clinician. If you have any doubts or questions seek advice from the patient leaflet provided with Lariam or from your clinician.
Taking Lariam:
If you start taking Lariam ten days before leaving for a high risk area, it should start working to help prevent malaria by the time that you leave.
It takes 6-24 hours for the active ingredient to enter your bloodstream, but by taking Lariam ten days in advance you’ll be able to deal with any side effects before you leave, and switch to another treatment if necessary. It also means that your body can get used to it before you travel.
If you miss a dose of Lariam, you should take the missed dose as soon as you remember. If it’s nearly time to take your next dose you should skip the missed dose and carry on as before. You shouldn’t take a double dose of Lariam.
If you accidentally take too much Lariam, contact a clinician for guidance.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Ministry of Defence.
Mefloquine for preventing malaria in non-immune adult travellers. Cochrane Database of Systematic Reviews.
Registered with GMC (No. 4624794)
Meet DanielRegistered with GPhC (No. 2202465)
Meet SanjedaRegistered with GPhC (No. 2070724)
Meet CraigDelivery, consultation, treatment. It’s all included in the price.
Quantity | Starting from |
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7 Tablets | £44.95 |
8 Tablets | £49.95 Save £1.42 |
9 Tablets | £56.95 |
10 Tablets | £61.95 Save £2.26 |
11 Tablets | £67.95 Save £2.69 |
12 Tablets | £73.95 Save £3.11 |
14 Tablets | £84.95 Save £4.95 |
Quantity | Starting from |
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16 Tablets | £86.95 |
23 Tablets | £114.95 Save £10.04 |
30 Tablets | £143.95 Save £19.08 |
37 Tablets | £172.95 Save £28.12 |
44 Tablets | £201.95 Save £37.16 |
51 Tablets | £229.95 Save £47.20 |
65 Tablets | £275.95 Save £77.28 |
Quantity | Starting from |
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37 Capsules | £28.95 |
44 Capsules | £39.95 |
51 Capsules | £51.95 |
58 Capsules | £63.95 |
65 Capsules | £74.95 |
72 Capsules | £86.95 |
86 Capsules | £97.95 |
Quantity | Starting from |
---|---|
16 Tablets | £86.95 |
23 Tablets | £114.95 Save £10.04 |
30 Tablets | £143.95 Save £19.08 |
37 Tablets | £172.95 Save £28.12 |
44 Tablets | £201.95 Save £37.16 |
51 Tablets | £229.95 Save £47.20 |
65 Tablets | £275.95 Save £77.28 |
Quantity | Starting from |
---|---|
16 Tablets | £56.95 |
23 Tablets | £73.95 Save £7.92 |
30 Tablets | £89.95 Save £16.83 |
37 Tablets | £107.95 Save £23.75 |
44 Tablets | £125.95 Save £30.66 |
51 Tablets | £142.95 Save £38.58 |
65 Tablets | £171.95 Save £59.41 |
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Malaria prevention: Here are some other options.
Like Malarone, but generic. A daily tablet that you start two days before travelling to prevent malaria.
Take two days before travel to prevent malaria, and for one month after you return.
Works in most malarious regions. Once daily tablet you start 2 days before travel.
Like Malarone, but doesn't need a prescription. Start two days before you enter a malaria risk zone.
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Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
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