Migraine relief that melts on the tongue.
Vydura is a migraine treatment that can prevent and relieve symptoms. It comes in the form of an oral lyophilisate, which is a wafer that melts under your tongue.
Start a consultation and get tailored options to manage your migraines. Order Vydura online and get it delivered as soon as the next working day.
Vydura is a treatment for migraines that can be used for episodes with or without aura. It’s a wafer-like orodispersible, which melts in your mouth. You place it on or under your tongue, and the medication dissolves to be absorbed by your body. It can be used to treat acute migraine episodes as they happen, or as a preventative treatment if you have more than four attacks a month.
Migraines are throbbing headaches that usually affect one side of the head. They can cause sensitivity to light, dizziness, and difficulty speaking. If you suffer from migraines, you’ll know how overbearing they can be, and the impact they can have on your daily life.
Vydura works by targeting a substance in your body called calcitonin gene-related peptide (CGRP). CGRP is a chemical messenger that’s known to contribute to migraines. The active ingredient in Vydura, rimegepant, blocks CGRP. This can help reduce the severity of migraines, and even prevent them from starting.
Vydura comes in a single dose — each oral lyophilisate contains 75mg of rimegepant. The maximum dose is one orodispersible (wafer) per day. Taking more than one won’t help improve your migraine symptoms and should be avoided.
If you feel like one dose of Vydura a day isn’t relieving your migraine symptoms, you can talk to a clinician about trying an alternative treatment.
If you’re using Vydura to treat migraines that have already started, you’ll be told to take one orodispersible when your attack comes on. If you’re using Vydura for migraine prevention, the usual dose is one orodispersible every other day.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Vydura is for oral use only, and can be taken with or without a meal. Because it dissolves under your tongue, there’s no need to take your dose with water.
Make sure your hands are dry when removing Vydura from its blister. Peel back the foil covering, gently remove the lyophilisate, and place it on or under your tongue. Because the lyophilisates are delicate, avoid pushing them through the foil like you might do with a regular tablet, as it could cause them to break.
Each dose of Vydura needs to be taken as soon as you’ve taken it out of the blister, and should never be stored elsewhere to take another time.
A study found that Vydura can provide relief from the main symptoms of a migraine attack within two hours of taking a dose, and provide sustained pain relief for between 2-48 hours. When compared with placebo, a significant amount of patients found Vydura helped them function normally two hours after their dose.
How long the medication takes to work might vary from person to person. If you’re taking Vydura every other day to prevent migraine attacks, it might be worth keeping a diary to see if the amount of migraines you get each week or month has reduced.
You should never take more than one lyophilisate (wafer) each day, as this is the maximum dose. If you know you’ve taken too much Vydura, go to hospital right away and seek urgent help. If you can, bring the box your medication arrived in along with the patient information leaflet (PIL). Doing so can help hospital staff decide the best course of action.
If you forget to take your usual Vydura tablet, avoid doubling-up the next day to make up for the missed dose. Instead, just skip the tablet you missed and carry on as normal.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Oral rimegepant for preventive treatment of migraine: a phase 2/3, randomised, double-blind, placebo-controlled trial. The Lancet, [online] 397(10268), pp.51–60.
Rimegepant for the treatment of migraine. Health Psychology Research, [online] 10(5).
“Calcitonin Gene-Related Peptide (CGRP): Role in Migraine Pathophysiology and Therapeutic Targeting.” Expert Opinion on Therapeutic Targets, vol. 24, no. 2, 1 Feb. 2020, pp. 91–100.
“VYDURA 75 Mg Oral Lyophilisate - Summary of Product Characteristics (SmPC) - (Emc).” Www.medicines.org.uk
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Meet CraigDelivery, consultation, treatment. It’s all included in the price.
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2 Oral Lyophilisate | £65.95 |
8 Oral Lyophilisate | £179.95 Save £83.85 |
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3 Tablets | £28.95 |
6 Tablets | £39.95 Save £17.95 |
9 Tablets | £51.95 Save £34.90 |
12 Tablets | £63.95 Save £51.85 |
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6 Tablets | £53.95 |
12 Tablets | £87.95 Save £19.95 |
18 Tablets | £119.95 Save £41.90 |
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2 Pack | £48.95 |
4 Pack | £82.95 Save £14.95 |
6 Pack | £112.95 Save £33.90 |
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2 Pack | £45.95 |
4 Pack | £79.95 Save £11.95 |
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6 Tablets | £82.95 |
12 Tablets | £149.95 Save £15.95 |
18 Tablets | £209.95 Save £38.90 |
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6 Tablets | £119.95 |
12 Tablets | £228.95 Save £10.95 |
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6 Tablets | £61.95 |
12 Tablets | £107.95 Save £15.95 |
18 Tablets | £153.95 Save £31.90 |
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6 Tablets | £72.95 |
12 Tablets | £129.95 Save £15.95 |
18 Tablets | £182.95 Save £35.90 |
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3 Tablets | £45.95 |
6 Tablets | £79.95 Save £11.95 |
9 Tablets | £114.95 Save £22.90 |
12 Tablets | £137.95 Save £45.85 |
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3 Oral Lyophilisates | £44.95 |
6 Oral Lyophilisates | £74.95 Save £14.95 |
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6 Tablets | £26.95 |
12 Tablets | £37.95 Save £15.95 |
18 Tablets | £49.95 Save £30.90 |
Quantity | Starting from |
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3 Tablets | £47.95 |
6 Tablets | £79.95 Save £15.95 |
12 Tablets | £111.95 Save £79.85 |
Quantity | Starting from |
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3 Tablets | £32.95 |
6 Tablets | £49.95 Save £15.95 |
9 Tablets | £66.95 Save £31.90 |
12 Tablets | £82.95 Save £48.85 |
Quantity | Starting from |
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3 Tablets | £26.95 |
6 Tablets | £37.95 Save £15.95 |
9 Tablets | £49.95 Save £30.90 |
12 Tablets | £59.95 Save £47.85 |
Quantity | Starting from |
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6 Tablets | £28.95 |
12 Tablets | £39.95 Save £17.95 |
18 Tablets | £51.95 Save £34.90 |
Quantity | Starting from |
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6 Tablets | £28.95 |
12 Tablets | £39.95 Save £17.95 |
Quantity | Starting from |
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6 Tablets | £26.95 |
12 Tablets | £37.95 Save £15.95 |
18 Tablets | £49.95 Save £30.90 |
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6 Tablets | £89.95 |
12 Tablets | £171.95 Save £7.95 |
18 Tablets | £228.95 Save £40.90 |
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6 Tablets | £36.95 |
12 Tablets | £59.95 Save £13.95 |
18 Tablets | £82.95 Save £27.90 |
Quantity | Starting from |
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6 Tablets | £36.95 |
12 Tablets | £59.95 Save £13.95 |
18 Tablets | £82.95 Save £27.90 |
Quantity | Starting from |
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6 Tablets | £66.95 |
12 Tablets | £112.95 Save £20.95 |
18 Tablets | £158.95 Save £41.90 |
Quantity | Starting from |
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6 Tablets | £66.95 |
12 Tablets | £119.95 Save £13.95 |
18 Tablets | £165.95 Save £34.90 |
Quantity | Starting from |
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6 Tablets | £66.95 |
12 Tablets | £119.95 Save £13.95 |
18 Tablets | £165.95 Save £34.90 |
Quantity | Starting from |
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6 Dose | £91.95 |
12 Dose | £169.95 Save £13.95 |
18 Dose | £227.95 Save £47.90 |
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Migraine: Here are some other options.
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Branded version of Rizatriptan. Comes as both a tablet or an orodispersible for quick and easy migraine relief.
The generic version of Naramig. Works in the body for 6 hours to treat your symptoms.
Generic version of Maxalt. Can provide effective migraine relief within two hours.
Generic tablet. Similar to Imigran. Suitable for migraines with or without aura.
Generic version of Zomig. Comes as a regular or melt in the mouth tablet.
Branded version of Zolmitriptan. Available as tablets or nasal spray for fast symptom relief.
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