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Reviewed on Nov 25, 2025. by Dr Alexandra Cristina Cowell Writer & Clinical Content Reviewer Registered with GPhC (No. 2241935) Next review due on November 27, 2028.
Dr Alexandra Cristina Cowell

Last updated on Nov 25, 2025.

Product info

  • Rizatriptan tablets are a migraine-relief treatment you take when you get symptoms.

  • Rizatriptan re-constricts blood vessels in the brain that widen during migraines to ease symptoms.
  • Can relieve your migraine symptoms within thirty minutes of taking a tablet.

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£48.95
  • Prices include:
    Express shipping

    24 hour shipping by secure courier.

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
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    Save £0.00 each order
Rizatriptan Rizatriptan

What is Rizatriptan?

Rizatriptan is a tablet treatment that relieves the symptoms of migraine with or without aura. It’s a selective serotonin receptor agonist, and like sumatriptan, almotriptan, frovatriptan, naratriptan and eletriptan, it’s a treatment that’s been specifically formulated to treat migraines. These treatments are frequently known as ‘triptans’ (for obvious reasons), and they all work in largely the same way.

Triptans like Rizatriotan don’t work to prevent migraine headaches from occurring, they should only be used to help your symptoms when they occur. If you suffer frequent migraines, you might be encouraged to try to identify what causes your migraines by keeping a diary in order to reduce them.

How does Rizatriptan work?

It’s thought that migraine symptoms start when temporary changes to your brain’s chemistry cause blood vessels to widen. Rizatriptan binds to your serotonin receptors, which makes the blood vessels around your brain narrow, reducing the transmission of pain signals to improve your symptoms.

Because Rizatriptan has a specific method of action, it shouldn’t be taken for regular tension headaches, or for any other pain relief. Using too many painkillers or triptans can lead to something called medication overuse headache – where headaches start being caused as a result of withdrawal symptoms. [1]

What doses of Rizatriptan are there?

There are two doses of Rizatriptan: 5mg and 10mg. The recommended dose is 10mg, unless you are taking propranolol, or have kidney or liver problems. If this is the case, then you’ll likely be prescribed the 5mg dose.

Treated trusted sources:

  1. Fischer, M.A. and Jan, A. (2020). Medication-overuse Headache (MOH). [online] PubMed.
treated.com This page was written by The Treated Content Team.
Dr Alexandra Cristina Cowell 1218322
This page was medically reviewed by Dr Alexandra Cristina Cowell on November 25, 2025. Next review due on November 27, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Rizatriptan Rizatriptan

How to take Rizatriptan

You should always take Rizatriptan exactly as instructed by your clinician. To take Rizatriptan, simply swallow one tablet, whole, with liquid. You should then wait at least two hours before taking another tablet if your symptoms come back. Don’t take more than one tablet for the same migraine attack.

How long does it take Rizatriptan to work?

Rizatriptan should start to get to work to help your symptoms within two hours of taking it. [1] If you don’t feel like your symptoms are improving, don’t take an additional tablet for the same migraine attack. Instead, contact a clinician for guidance.

What should I do if I make a mistake when taking Rizatriptan?

Try to always make sure you follow your clinician’s guidance when taking Rizatriptan. If you’ve taken too much and feel unwell, seek medical help straight away.

Treated trusted sources:

  1. Tfelt-Hansen, P., Teall, J., Rodriguez, F., Giacovazzo, M., Paz, J., Malbecq, W., Block, G.A., Reines, S.A. and Visser, W.H. (1998). Oral Rizatriptan Versus Oral Sumatriptan: A Direct Comparative Study in the Acute Treatment of Migraine. Headache: The Journal of Head and Face Pain, [online] 38(10), pp.748–755.
treated.com This page was written by The Treated Content Team.
Dr Alexandra Cristina Cowell 1218322
This page was medically reviewed by Dr Alexandra Cristina Cowell on November 25, 2025. Next review due on November 27, 2028.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Rizatriptan Rizatriptan

Rizatriptan isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.

Rizatriptan Rizatriptan

FAQ: Rizatriptan

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

How is Rizatriptan different from other treatments for migraine?

Answer:
Migraine treatments usually come in the form of one of:

  • painkillers

  • antiemetics (anti-sickness medicines)

  • triptans

  • combination treatments (usually a combination of painkiller and antiemetic)


Rizatriptan, as a triptan, has a similar mode of action to other triptans, in that it binds to your serotonin receptors in order to reduce the swelling of your brain’s blood vessels and reduce your symptoms. But different triptans can suit some people more or less than other people. Also, some triptans, like frovatriptan, stay in your system for a long time (but take a while to work), whereas other triptans, like sumatriptan, can start to get to work quickly to help your symptoms but don’t stay in your system for as long. [1]

Finding the best treatment for you can sometimes take a bit of trial and error. If you’re not sure where to start, talk to us about your health and our expert team can point you in the right direction.

Is Rizatriptan similar to any other treatments?

Answer:
There’s a branded equivalent of Rizatriptan, called Maxalt. Both Rizatriptan and Maxalt are available as 5 and 10mg tablets, but Maxalt is also available as 5 and 10 mg oral lyophilisates and Rizatriptan is also available as 5 and 10mg orodispersable tablets, which dissolve in the mouth. They’ll work in much the same way to treat your symptoms - they’re just produced by different companies in different labs.

Branded medicines are usually a bit more expensive than generics, so you might find that Maxalt can cost a little more than Rizatriptan.

Which version of Rizatriptan should I use?

Answer:
The standard dose of Rizatriptan is 10mg, though you may be prescribed 5mg if you have a history of liver or kidney problems. There’s also an orodispersible tablet of Rizatriptan that melts on the tongue, which you might prefer to use if you struggle to swallow tablets.

Do I need a prescription for Rizatriptan?

Answer:
Yes, you need a prescription for Rizatriptan.

Triptans aren’t suitable for everyone, and a clinician is going to want to be sure that you suffer from migraine headaches and not a different kind of headache, or that your symptoms aren’t being caused by another condition.

Treated trusted sources:

  1. Tfelt-Hansen, P., De Vries, P. and Saxena, P.R. (2000). Triptans in Migraine. Drugs, [online] 60(6), pp.1259–1287.

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