Lymecycline

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Reviewed on July 09, 2026. by Dr Alexandra Cristina Cowell Writer & Clinical Content Reviewer Registered with GPhC (No. 2241935) Next review due on Jul 05, 2029.

Last updated on July 09, 2026.

Product info

Lymecycline is an antibiotic with anti-inflammatory properties that treats perioral dermatitis.
It stops bacteria and reduces inflammation to relieve your symptoms.
Comes in oral capsules that you take each morning. Treatment can last several weeks or months.

Price checker

Prices include:

Express shipping
24 hour shipping by secure courier.
Consultation + Access to our clinicians
Ask our experts anything you like, any time you want.
Total
£44.95

Save £0.00 each order

Lymecycline: essential info
Lymecycline: instructions
Important stuff you need to know
FAQ

What is Lymecycline?

Lymecycline is an antibiotic. It has anti-inflammatory and antibacterial properties that prevent the growth of bacteria. ^[1] It’s typically prescribed to treat skin conditions like acne or perioral dermatitis.

Perioral dermatitis is a condition that’s characterised by a red rash around the face. It can be confused with acne as both are red, itchy and have acne-like breakouts. The exact cause is unknown, but the inflammation of the hair follicles and vessels leads to spots commonly around the mouth. ^[2]It’s normally treated with topical calcineurin inhibitors, or antibiotics if creams don’t work.

How does Lymecycline work?

Lymecycline is in a category of drugs called tetracyclines. The way drugs in this category work is by binding to the ribosome (the part that makes protein) which stops the production of proteins. The lack of proteins prevents the growth of bacteria, which eventually kills them. It also lowers inflammation by reducing the amount of fatty acids in sebum (the oily substance present on the skin).^[3] Excess fatty acids can cause spots, so reducing it can decrease them.

Treated trusted sources:

Tolino E, Skroza N, Mambrin A, Proietti I, Bernardini N, Balduzzi V, Marchesiello A, Di Fraia M, Michelini S, Potenza C. An Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris. J Clin Aesthet Dermatol. 2021 May;14(5):56-58. Epub 2021 May 1. PMID: 34188751; PMCID: PMC8211333.
Tolaymat L, Hall MR. Perioral Dermatitis. [Updated 2023 Apr 17]. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023
Alomar A, Berth-Jones J, Bos JD, Giannetti A, Reitamo S, Ruzicka T, Stalder JF, Thestrup-Pedersen K; European Working Group on Atopic Dermatitis. The role of topical calcineurin inhibitors in atopic dermatitis. Br J Dermatol. 2004 Dec;151 Suppl 70 Dec 2004:3-27. doi: 10.1111/j.1365-2133.2004.06269.x. PMID: 15548171.

This page was written by The Treated Content Team.

This page was medically reviewed by Dr Alexandra Cristina Cowell on July 03, 2026. Next review due on July 05, 2029.

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