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Gout is a form of arthritis that causes sudden joint pain, often in your big toe. But it can also affect other parts of the body, including your hands, wrists, knees and elbows.
Managing gout involves knowing how to treat a flare up, as well as combining lifestyle and dietary changes with medications, if needed, to keep long-term symptoms at bay. Here, we’ll look at the best ways to manage gout effectively and explain what your treatment journey might look like.

Although there are things you can try that might naturally prevent a gout attack, treating a flare up once it starts involves controlling pain and inflammation in the affected joint.
Often, common over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are recommended, as they work fast to control swelling.
Gout attacks trigger an immune response that increases prostaglandin production, fat-based chemical messengers that are produced whenever you have inflammation.
NSAIDs work by blocking your body from making prostaglandins when uric acid crystals are deposited in joints during a gout attack. By stopping prostaglandin production, NSAIDs calm this automatic inflammatory response down, which can help to ease pain and swelling during a gout flare up.
There are other prescription-strength NSAIDs that are used to manage gout which are stronger than ibuprofen, such as Naproxen, which can be taken as tablets or as an oral solution. As well as being used to treat gout, Naproxen is also prescribed for dental or muscle issues, or conditions like ankylosing spondylitis which affect joints in the back and neck.
Another option for treating gout flare ups is Colchicine, which treats inflammation by reducing the activation of white blood cells during an attack. Colchicine usually starts to work within thirty minutes to two hours of taking it, but it can sometimes take a couple of days to start reducing your pain effectively.
Using anti-inflammatory medications alongside adjusting your diet and activity levels might mean that you’re able to control your gout without the need for long-term treatments after an initial flare up.
But around 62% of people who experience an acute attack can experience another gout flare up within a year, which means you might need to consider medications that prevent gout attacks before they start.
One commonly prescribed long-term gout medication is Allopurinol (also known as Zyloric), which is considered a first-line treatment.
By reducing your uric acid levels, Allopurinol reduces the chances of uric acid crystals forming, which flare up and cause gout attacks. It’s a tablet that’s available in two doses, and you’ll usually be started on the lowest dose first to see if that works effectively at controlling your gout.
Another long-term gout treatment is Adenuric, which contains febuxostat, which works in a similar way to allopurinol and reduces your uric acid levels. It’s a tablet you take daily, and it’s also available in two strengths.
Medications like Allopurinol and Adenuric, which lower the levels of urate (uric acid) in your blood, can sometimes cause a temporary gout flare-up.
This is normal, and usually not anything to worry about. If this does occur, you might be advised to use an anti-inflammatory treatment (like an NSAID) to treat flare ups until your long-term medication has settled in your system.
If you get flare-ups often when you start a medication that works by lowering uric acid levels, it might be that your dose needs adjusting. To avoid this, and other side effects the treatments might cause, your clinician will usually advise you to start on the lowest available dose so your body can get used to it.
If lifestyle changes and taking anti-inflammatory medications like Naproxen or Ibuprofen during a gout flare up don’t work well enough to control your symptoms, your clinician might suggest having a blood test to measure your uric acid levels.
If your results show you might benefit from starting a gout treatment that you take regularly, they’ll recommend some options for you. After a month or so of using medication, they’ll suggest getting another blood test done to check your uric acid levels again. This helps your clinician decide the right dose for you going forward, or if they think you’d benefit from trying a different treatment.
Gout is caused by a build up of uric acid, but it can have many different contributing factors, such as diet, lifestyle, existing health conditions and medications. Because there’s such a wide variety of factors which can exacerbate gout symptoms, treatment plans will vary from person to person.
But there are some lifestyle adjustments that everyone who experiences gout can try, which might improve their symptoms.
Quitting smoking, exercising more often, limiting red meat and shellfish, and staying hydrated are some examples of ways you can prevent gout.
So alongside medications like Allopurinal, Colchichine and NSAIDs that might be prescribed to treat gout, your clinician might take a broader look at your lifestyle to see if there are any changes you can make to try and manage gout naturally.
Our clinicians can help you manage gout effectively. They’ll help you choose the right medication and dosage, and develop a tailored treatment plan built around your personal health.
As well as suggesting treatments, your clinician can advise you about lifestyle changes you can make that might improve your gout, such as exercising regularly and using vitamin C supplements or adding more to your diet.
And once you start a treatment, they’ll check in with you regularly as part of our ongoing aftercare to make sure you’re happy with your plan.
Prostaglandins and Inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology, 31(5), pp.986–1000.
How common are side-effects of treatment to prevent gout flares when starting allopurinol?
Connor, M. (2008). Allopurinol for pain relief: more than just crystal clearance? British Journal of Pharmacology, 156(1), pp.4–6.
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Last updated on Aug 27, 2026.
Our experts continually monitor new findings in health and medicine, and we update our articles when new info becomes available.
Aug 27, 2026
Published by: The Treated Content Team. Medically reviewed by: Dr Alexandra Cristina Cowell, Writer & Clinical Content ReviewerHow we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Writer & Clinical Content Reviewer
Cristina writes content for Treated, and reviews content produced by our other writers to make sure it’s clinically accurate.
MeetHow we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.