Once-daily tablet for long-term treatment of GORD.
Rabeprazole tablets are for the treatment of moderate to severe gastro-oesophageal reflux disease (or GORD for short). It can also treat stomach ulcers and stomach infections.
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Rabeprazole is a generic treatment for several gastro-related conditions like GORD and stomach ulcers. It’s part of a group of medicines called proton pump inhibitors (PPIs). Rabeprazole works by reducing the amount of acid made by the stomach, alleviating symptoms such as heartburn and acid reflux. It can also reverse damage to the oesophagus and prevent stomach ulcers.
It’s also used to treat a condition called Zollinger-Ellison syndrome, which is where the stomach produces an excessive amount of acid caused by a growth in the pancreas, as well as H. pylori infections in people with peptic ulcer disease.
Rabeprazole works by reducing the amount of acid your stomach makes. GORD is a recurring condition where you experience acid reflux, heartburn, stomach ulcers, and inflammation around your oesophagus and gullet.
Rabeprazole, similar to other PPIs, stops the ‘proton pump’ (a chemical system in the cells of your stomach lining that produces acid) from working properly. This then reduces the amount of acid in the stomach, relieving symptoms of GORD, healing the stomach lining from ulcers, and preventing damage to the oesophagus.
It also comes as a delayed-release tablet, which means the medication will be released in the intestine where it’s needed (rather than being broken down by stomach acids). This allows Rabeprazole to be more effective for longer, because it binds better to the proton pump.
Rabeprazole is available in either 10 mg or 20 mg of rabeprazole tablets. To treat symptoms of GORD (heartburn and acid reflux), the usual dose is 10 to 20 mg a day. For stomach ulcers, the dose is 20 mg a day.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
There are several ways to take Rabeprazole, depending on the severity and type of your condition. Your prescriber will tell you how to take it safely. We’ll outline the guidelines for taking Rabeprazole for GORD below.
To take Rabeprazole:
For GORD ulcers:
For GORD maintenance:
For symptomatic GORD:
You should be able to feel the effects of Rabeprazole within a few days, but it can take up to four weeks for it to work fully. It can take four to eight weeks to treat stomach ulcers, and longer still for the maintenance of GORD. For symptomatic GORD you usually take it only when you need it, and then you can stop once your symptoms have stopped.
Studies have shown that rabeprazole, compared with other PPIs, is very close behind esomeprazole to have the most rapid action.
If you’ve forgotten to take Rabeprazole, take a tablet as soon as you remember. Don’t take a double dose to make up for the forgotten dose. If you take more than you should, seek urgent medical attention as soon as possible.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Medicines: rabeprazole: about rabeprazole, nhs.uk
“Comparison of the effects of esomeprazole 40 mg, rabeprazole 20 mg, lansoprazole 30 mg, and pantoprazole 40 mg on intragastrıc pH in extensive metabolizer patients with gastroesophageal reflux disease.” The Turkish journal of gastroenterology: the official journal of Turkish Society of Gastroenterology vol. 27,5 (2016): 408-414. doi:10.5152/tjg.2016.15514
“Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study.” Gut vol. 67,1 (2018): 28-35. doi:10.1136/gutjnl-2017-314605
“Rabeprazole in treatment of acid peptic diseases: results of three placebo-controlled dose-response clinical trials in duodenal ulcer, gastric ulcer, and gastroesophageal reflux disease (GERD). The Rabeprazole Study Group.” Digestive diseases and sciences vol. 43,5 (1998): 993-1000. doi:10.1023/a:1018822532736
“Efficacy of rabeprazole once daily for acid-related disorders.” Digestive diseases and sciences vol. 46,3 (2001): 587-96. doi:10.1023/a:1005659518030
“Rabeprazole: an update of its use in acid-related disorders.” Drugs vol. 61,15 (2001): 2327-56. doi:10.2165/00003495-200161150-00016
“Rabeprazole: an update of its use in acid-related disorders.” Drugs vol. 61,15 (2001): 2327-56. doi:10.2165/00003495-200161150-00016
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GORD: Here are some other options.
Generic version of Ventra. Tablets that soothe symptoms of acid reflux.
Generic capsule that you take daily to reduce the amount of acid in your stomach.
Branded treatment for GORD that's available as either a capsule or pellets.
Like Esomeprazole, but branded. Tablets or granules available in a 10mg, 20mg or 40mg dose.
Generic version of Losec. Can treat GORD, heartburn and stomach ulcers too.
Gastro-resistant tablet that stops stomach acid from entering the throat.
Daily GORD relief tablets that come in two doses. Can also treat stomach ulcers.
One a day oro-dispersible tablet for managing GORD. Available in two doses.
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