Oestrogen only HRT patch that you replace twice a week.

Estraderm transdermal patches deliver oestrogen-only hormone replacement therapy (HRT) to help you manage your post-menopause symptoms.
Answer a few questions about your health, and we’ll find the right HRT treatments for you. Order Estraderm MX online and we’ll deliver it to your door.
Estraderm is an oestrogen-only HRT patch that releases oestrogen into the skin. This delivery method makes it quick and easy to use. You can get a month-long pack with eight patches, or a three month pack with 24 patches.
The active ingredient in Estraderm MX is estradiol, which is produced naturally in your body. It is also the strongest form of oestrogen.
Estraderm delivers estradiol through your skin. It’s a sticky patch that you wear for several days before you take it off and replace it with a new one.
Oestrogen-only HRT like Estraderm increases the levels of oestrogen in your body. This relieves post-menopausal symptoms including hot flushes, night sweats and sleeping difficulties. It also protects you against osteoporosis, or weak bones, which can develop in some women after the menopause.
Women who haven’t had a period for at least one year can take Estraderm MX to help decrease post-menopause symptoms.
Estraderm MX may be a more appropriate treatment option for women who have had a hysterectomy. Women who still have a uterus will need to take an additional progestogen alongside Estraderm, as oestrogen in isolation can cause the womb-lining to keep growing. Without a separate progestogen to manage this, it can increase your risk of endometrial cancer. The additional progestogen could come from a Mirena contraceptive ‘coil’ (or similar) or in the form of a gel or tablet.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Beginning a HRT treatment should be easy. There are different guidelines for how you should start your journey with Estraderm MX.
When you’re ready to start taking Estraderm MX, remove the clear film from the patch and stick it on a hairless section of skin below your waist. Most patients choose their buttocks, but you can also place it on your lower back, hip, or abdomen. You’ll replace the patch every three or four days. It’s easiest if you designate the same two days to apply a patch, like Monday and Thursday or Wednesday and Saturday. Patches can’t be reused.
Don’t put Estraderm on or near your breasts or on broken or irritated skin. If you forget to replace your patch, put a new one on as soon as you remember. Keep switching your patches on the same days as before.
Research into the effectiveness of Estraderm MX and other oestrogen-only patches is limited. Most studies measure effectiveness by the frequency of hot flushes while using HRT. Post-menopausal women who took HRT drugs experienced hot flushes 84% less often.
Estraderm MX is available in four different doses and the amount of oestrogen absorbed through your skin varies with each dose:
If you are on Estraderm MX and your post-menopause symptoms aren’t easing, our clinician can increase your dose. If you’re experiencing side effects like redness, itching, breakthrough bleeding, or headaches, our clinician may reduce your dose. Just sign in to your account and send our clinician a message, and they can chat to you about changing your dose.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Overview - Hormone replacement therapy (HRT). NHS.
Clinical efficacy of estradiol transdermal system in the treatment of hot flashes in postmenopausal women. Research and Reports in Transdermal Drug Delivery.
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Menopause (HRT): Here are some other options.
Oestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.
Simple treatment for menopause symptoms. Estradot is a HRT patch you change just twice a week.
Sequential dose patch. Use to manage menopause symptoms if you still have periods.
Continuous combined HRT pill. Made for menopause symptoms if you haven't had a period in 1 year.
Like Kliofem, but half the dose. HRT pill that’s good if you're sensitive to hormones.
A daily tablet for post-menopausal symptoms. It’s hormone-free, but works just like female hormones.
HRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.
Combined treatment for menopause relief. Sequential pills for women who no longer have periods.
Oestrogen-only pill for menopause treatment. Same hormones as Elleste Solo, different brand.
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Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
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