Oestrogen-only HRT, in a patch or tablet.

Progynova comes in tablets and skin patches that deliver oestrogen-only HRT. This helps to relieve symptoms of the menopause.
After answering some questions from our clinicians, we can find the HRT treatment that best fits you. We’re listening – choose your HRT and order Progynova online.
Progynova is an oestrogen-only HRT treatment that comes as either a tablet or a skin patch that you change once a week. Progynova tablets are used to relieve symptoms of perimenopause – this is the start of menopause where you’ll start to experience irregular periods. Progynova patches are for postmenopausal women (who haven’t had a period in over 12 months).
Women go through menopause because their levels of oestrogen and progesterone – hormones produced by the ovaries – go down naturally as they get older. This can cause symptoms like hot flushes, low mood, anxiety, and vaginal pain or dryness. Progynova balances the level of oestrogen in your body to help lessen the symptoms of menopause.
Progynova is suitable for women who have had their uterus removed (a hysterectomy). This is because both Progynova tablets and patches are oestrogen-only HRT treatments, containing the active ingredient estradiol (Progynova tablets use estradiol valerate, and the patches estradiol hemihydrate). When oestrogens are used alone for a long time, the risk of illnesses such as endometrial cancer (cancer of the womb’s lining) increases.
You can take Progynova if you have not had a hysterectomy, but only alongside a progesterone treatment that reduces the increased risk of endometrial cancer. But most commonly, if you have not had a hysterectomy, we offer various combined HRT treatments that include progesterone.
We offer Progynova 1mg and 2mg tablets, as well as Progynova TS 50mcg and 100mcg transdermal patches. Larger doses such as Progynova 6mg and 8mg tablets are also available, but we do not offer these.
If you’re prescribed Progynova tablets, you’ll need to take them once per day. If you’re using the patches, they only need to be changed once a week.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
How you take Progynova will be different depending on whether you’re using tablets or skin patches. You should always follow our clinician’s guidance to get the best results from your treatment while reducing any possible side-effects. If you’re not sure which treatment is right for you, speak to us and we can help advise you.
You should typically take a single 1mg or 2mg tablet of Progynova once a day with or without food. This will depend on your prescription.
You shouldn’t use Progynova patches until at least twelve months have passed since your last period, or if you haven’t had a hysterectomy. To use your patches:
If you were taking other HRT treatment continuously before starting Progynova patches, finish your current pack before starting Progynova the next day. Don’t have a break between your old treatment and your new treatment.
You might be instructed to include a gap week in your HRT treatment. If so, apply one patch per week for three weeks, then take a seven-day break before starting again with your next patch. If you were taking HRT treatment with a gap week before Progynova patches, you should start your new course immediately after the gap days.
Only ever take one tablet per day or apply one patch at a time. No treatment is needed if you take too much Progynova, but it may cause sickness or menstruation-like bleeding. If you’re using patches and experience this, you should remove the patches. If you’re concerned, speak with your doctor or clinician.
If you forget to apply your patch, apply a new one for the remainder of your seven day cycle. If your patch falls off before it has been on for seven days, you can either reapply it or use a new one for the rest of the seven days. If you leave your patch off for multiple days, you could have some spotting or breakthrough bleeding.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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Menopause (HRT): Here are some other options.
Oestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.
Simple treatment for menopause symptoms. Estradot is a HRT patch you change just twice a week.
Sequential dose patch. Use to manage menopause symptoms if you still have periods.
Continuous combined HRT pill. Made for menopause symptoms if you haven't had a period in 1 year.
Like Kliofem, but half the dose. HRT pill that’s good if you're sensitive to hormones.
A daily tablet for post-menopausal symptoms. It’s hormone-free, but works just like female hormones.
HRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.
Combined treatment for menopause relief. Sequential pills for women who no longer have periods.
Oestrogen-only pill for menopause treatment. Same hormones as Elleste Solo, different brand.
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Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
‘Progynova 2mg tablets patient leaflet.’ Electronic Medicines Compendium, p. 2.
‘Progynova TS50 micrograms/24 hours transdermal patch.’ Electronic Medicines Compendium, p. 2.
‘Progynova Consumer Medicine Information.’ Medsafe: New Zealand Medicines and Medical Devices Safety Authority, p. 1.
‘Progynova 2mg tablets patient leaflet.’ Electronic Medicines Compendium, p. 8.
‘Weight gain and hormone replacement therapy: are women’s fears justified?’ Maturitas (2000), 34(1)
‘Methods for Endometrial Preparation in Frozen-Thawed Embryo Transfer Cycles’ Journal of the Turkish-German Gynecological Association.
‘Progynova Consumer Medicine Information.’ Medsafe: New Zealand Medicines and Medical Devices Safety Authority, p. 4.
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