Oestrogen-only HRT in a vaginal tablet.
Gina 10 microgram vaginal tablets are a type of HRT, also known as hormone replacement therapy. It’s designed to relieve symptoms of the menopause in your vagina, such as irritation or dryness.
If you’re looking for HRT online, take our consultation and we’ll recommend the treatments that suit you. Speak to our experts about your health, and order Gina HRT tablets online.
Gina HRT tablets are a type of local vaginal hormone replacement therapy. This means you insert the tablets directly into your vagina using the included applicators to relieve symptoms of menopause in the vagina. For example, this might include irritation or dryness.
Gina vaginal tablets are a type of oestrogen-only HRT, as their only active ingredient is estradiol (a form of oestrogen). Typically, oestrogen-only HRT treatments are best suited to women who have had a hysterectomy, as the increased level of oestrogen can increase the risk of certain conditions (such as breast cancer or blood clots) in women who have an intact uterus.
Because Gina is applied locally to the vagina (instead of systemically like an oral tablet or skin patch), very little is absorbed into your bloodstream. So it’s thought that the risk of developing side effects with Gina is lower than with systemic HRT. However, the only side effect currently confirmed to have reduced risk for certain is the increased possibility of developing breast cancer (if you haven’t had it in the past).
As women get older, the level of hormones their bodies produce begins to change. The menopausal transition is a period when two hormones made by the ovaries (oestrogen and progesterone) decrease naturally. In the years leading up to menopause, you may notice changes to your menstrual cycle, hot flushes, and other symptoms. This is known as perimenopause.
The menopause doesn’t actually occur until 12 months after your last period. After menopause, due to the reduced hormone levels in your body, you may get symptoms such as dryness and soreness in your vagina. Gina tablets provide oestrogen locally to replace the hormones your body is no longer producing. This helps to relieve vaginal discomfort.
Gina estradiol tablets are only for postmenopausal women over the age of 50 who haven’t had a period in over a year.
Usually, HRT treatments that contain just oestrogen are recommended for women who have had a hysterectomy. Women with an intact uterus can use them, but only alongside a progesterone treatment. This is because increasing the level of oestrogen in the body without also raising the level of progesterone can heighten the risk of breast and endometrial cancer, among other conditions.
However, as Gina menopause tablets are applied locally, directly into the vagina, it’s considered to have a lower risk of these adverse effects. This means it’s suitable to be used by women who haven’t had a hysterectomy.
This treatment only comes in one dose, the Gina 10 microgram vaginal tablet. Other vaginal estradiol tablets used to be available at a higher dose of 25mcg, such as Vagifem 25mcg. However, this dose has been discontinued after medical advice suggested women use the lowest effective dose of oestrogen; 10mcg tablets were shown to provide results that weren’t significantly different from the values of the 25mcg dose.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
You should always take Gina as instructed by your clinician.
If you’re taking Gina for the first time, or you’ve taken a break from Gina and your menopause symptoms have returned, you should start by using one tablet every day for two weeks. This initial dose will increase the local level of oestrogen in your vagina. After two weeks, you’ll switch to a maintenance dose of one tablet two times a week, leaving three to four days between doses. This altered dose is to maintain the increased level of oestrogen.
Follow these steps to take your Gina vaginal tablets:
Your symptoms should start to improve after a few months of taking Gina. If you find your symptoms are getting worse, you should contact your clinician. Likewise, if you’ve been taking Gina for three months and noticed no improvement in your symptoms, you should speak with your doctor or pharmacist.
Only take Gina as you’re told to by your clinician, and make sure to check your patient information leaflet if you need more details. The dosage of estradiol in Gina is very low, so even if you accidentally take more than you should, you’re unlikely to notice any side effects.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
Proposal to make Gina 10 microgram vaginal tablets (Estradiol) available from pharmacies. (Accessed 14 Dec 2022).
Gina 10 micrograms vaginal tablets: Estradiol. (Accessed 15 Dec 2022).
Vagifem 25microgram vaginal tablets (Dowelhurst Ltd). (Accessed 15 Dec 2022).
‘Efficacy and safety of ultra-low-dose Vagifem (10mcg)’, Patient Preference and Adherence. vol. 5. pp. 571-574. (Accessed 15 Dec 2022).
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Menopause (HRT): Here are some other options.
Oestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.
Combined continuous HRT patch. Used it's been more than 12 months since your last period.
Sequential dose patch. Use to manage menopause symptoms if you still have periods.
Comes as a continuous or sequential tablet, depending on whether you're still having periods.
HRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.
Oestrogen only tablet or patch for women who've had a hysterectomy, or used alongside a progesterone in combined HRT.
Generic version of Livial. Hormone-free HRT that can improve mood and libido.
The natural progesterone treatment. Taken alongside oestrogen to relieve symptoms of menopause.
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