Combined HRT tablet that relieves menopausal symptoms.

Kliofem is a combined form of HRT, so it’s got two hormones in it that tackle menopausal symptoms.
Chat to us about your health, and we’ll recommend HRT treatments that are tailored just for you. Order Kliofem online and get it on subscription.
Kliofem is a combined HRT tablet that helps to keep symptoms of the menopause under control. It’s suitable for postmenopausal women who haven’t had a period for over a year.
It’s also sometimes used to treat osteoporosis, which can develop after the menopause and cause fragile and brittle bones.
Because it’s a continuous combined HRT treatment, it needs to be taken on a daily basis. The tablet comes in a calendar pack to help you keep a track of your medication.
With the menopause, your ovaries start to produce less and less oestrogen. This reduction in oestrogen triggers symptoms like discomfort during sex, vaginal dryness, difficulty sleeping, hot flushes, night sweats and low mood or anxiety.
For some women, these symptoms can be uncomfortable, and the oestrogen in Kliofem, estradiol, helps to relieve them.
But on its own, the oestrogen in Kliofem can cause the womb to grow more than it should, which may result in womb cancer if it isn’t kept in line. And this is where the progesterone in combined HRT treatments like Kliofem comes in. It keeps the oestrogen in check.
It’s a continuous combined type of HRT, so it’s usually suitable for women who are postmenopausal (women who haven’t had a period for one year).
If you’re still having your period then, or if your womb has been removed, it won’t be the recommended treatment for you. Our clinician will usually recommend combined sequential or sequential HRT medications if you’re still getting your period, or oestrogen only options if you’ve had a hysterectomy.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Take one Kliofem tablet daily, at the same time. Once you have taken all 28 tablets in the pack, move on to your next one.
If a dose is missed, it should be taken within the next 12 hours. If more than 12 hours has passed, start taking the tablet as you would normally the following day.
If you’re looking to stop taking Kliofem, let our clinician know. They can talk you through the effects of stopping treatment, and explore other medications with you if you’re looking to switch to something else.
A clinical trial review for Kliofem showed the following results:
Kliofem also provides effective relief from postmenopausal symptoms, including hot flushes, vaginal dryness, mood swings, reduced sex drive and night sweats.
No. Kliofem is a single dose tablet that contains 2mg estradiol and 1mg norethisterone. If you find that the hormones on this dose trigger side effects, or if it isn’t working for you as well as it should, drop our clinician a message. They can chat through alternative HRT treatment options with you.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
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Meet RuaraidhDelivery, consultation, treatment. It’s all included in the price.
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84 Tablets | £47.95 |
168 Tablets | £77.95 Save £17.95 |
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84 Tablets | £39.95 |
168 Tablets | £63.95 Save £15.95 |
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84 Tablets | £39.95 |
168 Tablets | £63.95 Save £15.95 |
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8 Patches | £47.95 |
24 Patches | £87.95 Save £55.90 |
Quantity | Starting from |
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8 Patches | £47.95 |
24 Patches | £87.95 Save £55.90 |
Quantity | Starting from |
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84 Tablets | £51.95 |
168 Tablets | £87.95 Save £15.95 |
Quantity | Starting from |
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84 Tablets | £51.95 |
168 Tablets | £87.95 Save £15.95 |
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24 Tablets | £58.95 |
48 Tablets | £98.95 Save £18.95 |
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80 Gel | £35.95 |
160 Gel | £49.95 Save £21.95 |
240 Gel | £61.95 Save £45.90 |
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12 Patches | £55.95 |
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12 Patches | £55.95 |
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84 Tablets | £37.95 |
168 Tablets | £59.95 Save £15.95 |
Quantity | Starting from |
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84 Tablets | £37.95 |
168 Tablets | £59.95 Save £15.95 |
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28 Tablets | £33.95 |
56 Tablets | £47.95 Save £19.95 |
84 Tablets | £61.95 Save £39.90 |
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30 Tablets | £37.95 |
60 Tablets | £59.95 Save £15.95 |
90 Tablets | £81.95 Save £31.90 |
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Menopause (HRT): Here are some other options.
Oestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.
Combined continuous HRT patch. Used it's been more than 12 months since your last period.
Sequential dose patch. Use to manage menopause symptoms if you still have periods.
Comes as a continuous or sequential tablet, depending on whether you're still having periods.
Oestrogen-only HRT to tackle vaginal menopause symptoms.
HRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.
Oestrogen only tablet or patch for women who've had a hysterectomy, or used alongside a progesterone in combined HRT.
Generic version of Livial. Hormone-free HRT that can improve mood and libido.
The natural progesterone treatment. Taken alongside oestrogen to relieve symptoms of menopause.
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