The HRT that comes as a spray.

Lenzetto is a spray-form of HRT. Just apply it to your upper arm to get effective relief from the symptoms of menopause.
Order Lenzetto online with Treated and get the HRT you need, delivered right to your doorstep. Our clinicians are always a message away with expert advice for managing the menopause.
Lenzetto is a form of HRT (hormone replacement therapy) which is suitable for women who’ve either had no period for the last six months, or a hysterectomy. What makes Lenzetto unique is that it comes as a spray, whereas other HRTs will usually either be pills, patches or gels.
Lenzetto is an oestrogen-only form of HRT, that helps you deal with the symptoms of the menopause. So if you’re struggling with hot flushes, sleep disturbances, sexual problems or mood swings, Lenzetto can help.
Lenzetto is made from estradiol - a synthetic form of oestrogen. Each spray dispenses 90mcl of the liquid, which contains 1.53 mg of estradiol. Lenzetto spray works transdermally. This basically means that you just spray it onto your skin and the active ingredient absorbs through the top layer (called the dermis) and into your bloodstream.
When you go through the menopause, your body stops producing oestrogen at the same level that it used to, which contributes towards your symptoms. Lenzetto replaces your natural oestrogen in order to reduce these symptoms.
Lenzetto spray bottles only come in one size, but how many sprays you need per day will depend on your symptoms. Your clinician will usually recommend you start on the lowest dose, which is one spray per day. Using the lowest dose needed to help your symptoms can reduce the risk of side effects.
If you’re using multiple sprays per day, it’s best to apply them all at the same time. Just spray them on separate spots on your inner forearm, for as many sprays as you need.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Always read the patient information leaflet that comes with your medication, and talk to your clinician if you have any questions.
Lenzetto is absorbed into your bloodstream quickly, but it may take some time for you to notice a difference. Your clinician should review your Lenzetto dose every three-to-six months to make sure it’s still right for you.
Make sure not to rub the spray into your skin. If you get any on your hands while applying it, you should wash them with soap and water. Cover your skin with clothing two minutes after you spray Lenzetto. If anyone comes in contact with your skin, they should wash the area with soap and water.
If you forget to use Lenzetto, use it when you remember, unless it’s nearly time for your next dose. Then keep using it as normal. If you accidentally use too much, contact a clinician for advice if you have any worrying symptoms.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
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Meet CraigDelivery, consultation, treatment. It’s all included in the price.
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1 Spray | £37.95 |
2 Spray | £55.95 Save £19.95 |
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84 Tablets | £39.95 |
168 Tablets | £63.95 Save £15.95 |
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84 Tablets | £39.95 |
168 Tablets | £63.95 Save £15.95 |
Quantity | Starting from |
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8 Patches | £47.95 |
24 Patches | £87.95 Save £55.90 |
Quantity | Starting from |
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8 Patches | £47.95 |
24 Patches | £87.95 Save £55.90 |
Quantity | Starting from |
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84 Tablets | £51.95 |
168 Tablets | £87.95 Save £15.95 |
Quantity | Starting from |
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84 Tablets | £51.95 |
168 Tablets | £87.95 Save £15.95 |
Quantity | Starting from |
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24 Tablets | £58.95 |
48 Tablets | £98.95 Save £18.95 |
Quantity | Starting from |
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80 Gel | £35.95 |
160 Gel | £49.95 Save £21.95 |
240 Gel | £61.95 Save £45.90 |
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12 Patches | £55.95 |
Quantity | Starting from |
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12 Patches | £55.95 |
Quantity | Starting from |
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84 Tablets | £37.95 |
168 Tablets | £59.95 Save £15.95 |
Quantity | Starting from |
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84 Tablets | £37.95 |
168 Tablets | £59.95 Save £15.95 |
Quantity | Starting from |
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28 Tablets | £33.95 |
56 Tablets | £47.95 Save £19.95 |
84 Tablets | £61.95 Save £39.90 |
Quantity | Starting from |
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30 Tablets | £37.95 |
60 Tablets | £59.95 Save £15.95 |
90 Tablets | £81.95 Save £31.90 |
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Menopause (HRT): Here are some other options.
Oestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.
Combined continuous HRT patch. Used it's been more than 12 months since your last period.
Sequential dose patch. Use to manage menopause symptoms if you still have periods.
Comes as a continuous or sequential tablet, depending on whether you're still having periods.
Oestrogen-only HRT to tackle vaginal menopause symptoms.
HRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.
Oestrogen only tablet or patch for women who've had a hysterectomy, or used alongside a progesterone in combined HRT.
Generic version of Livial. Hormone-free HRT that can improve mood and libido.
The natural progesterone treatment. Taken alongside oestrogen to relieve symptoms of menopause.
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Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
Lenzetto 1.53 mg/spray, transdermal spray, solution, Patient Information Leaflet.
Oestrogen and progestogen hormone replacement therapy for peri-menopausal and post-menopausal women: weight and body fat distribution. Cochrane Database of Systematic Reviews.
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