Low-dose combined HRT, good for hormone sensitivity.

Premique is a combined hormone replacement therapy (HRT) treatment for post-menopausal women. It reduces menopause symptoms and can help to prevent osteoporosis in a once daily tablet.
Answer a few questions about your health, and we’ll recommend HRT treatments tailored just for you. Order Premique online and get your medication on subscription.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Taking Premique is quick and easy. Swallow one pill each day with or without food and water. Don’t skip any pills and don’t pause in between packs.
If you aren’t currently taking any HRT medications, you can begin taking Premique at any time. If you’re making the switch from another continuous combined HRT option, you can also start at any time. However, if you’re switching from a different kind of HRT, you will need to start Premique after completing your last cycle.
If you miss a dose of Premique, take it as soon as you remember. If you missed more than one dose, only take the most recently forgotten one before continuing as usual. Never take a double dose.
Premique is proven to be an effective HRT treatment for post-menopausal women. It provides significant health benefits while causing fewer side effects than higher dose HRT options .
There are two different doses available for Premique. If you’re taking HRT for the first time, our clinician will start you on the low dose option with 0.3mg of conjugated estrogens and 1.5mg of medroxyprogesterone acetate.
If you are still experiencing menopause symptoms that are interfering with your daily life, our clinician may bump you up to the higher dose with 0.625mg of conjugated estrogens and 5mg of medroxyprogesterone acetate.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
A cost-utility analysis of low-dose hormone replacement therapy in postmenopausal women with an intact uterus. Current Medical Research and Opinion, 21(12), pp.2051–2061.
Weight gain and hormone replacement therapy: are women’s fears justified? Maturitas, 34, pp.S3–S8.
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Quantity | Starting from |
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84 M/R Tablets | £79.95 |
168 M/R Tablets | £137.95 Save £21.95 |
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84 Tablets | £39.95 |
168 Tablets | £63.95 Save £15.95 |
Quantity | Starting from |
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84 Tablets | £39.95 |
168 Tablets | £63.95 Save £15.95 |
Quantity | Starting from |
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8 Patches | £47.95 |
24 Patches | £87.95 Save £55.90 |
Quantity | Starting from |
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8 Patches | £47.95 |
24 Patches | £87.95 Save £55.90 |
Quantity | Starting from |
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84 Tablets | £51.95 |
168 Tablets | £87.95 Save £15.95 |
Quantity | Starting from |
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84 Tablets | £51.95 |
168 Tablets | £87.95 Save £15.95 |
Quantity | Starting from |
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24 Tablets | £58.95 |
48 Tablets | £98.95 Save £18.95 |
Quantity | Starting from |
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80 Gel | £35.95 |
160 Gel | £49.95 Save £21.95 |
240 Gel | £61.95 Save £45.90 |
Quantity | Starting from |
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12 Patches | £55.95 |
Quantity | Starting from |
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12 Patches | £55.95 |
Quantity | Starting from |
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84 Tablets | £37.95 |
168 Tablets | £59.95 Save £15.95 |
Quantity | Starting from |
---|---|
84 Tablets | £37.95 |
168 Tablets | £59.95 Save £15.95 |
Quantity | Starting from |
---|---|
28 Tablets | £33.95 |
56 Tablets | £47.95 Save £19.95 |
84 Tablets | £61.95 Save £39.90 |
Quantity | Starting from |
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30 Tablets | £37.95 |
60 Tablets | £59.95 Save £15.95 |
90 Tablets | £81.95 Save £31.90 |
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Menopause (HRT): Here are some other options.
Oestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.
Combined continuous HRT patch. Used it's been more than 12 months since your last period.
Sequential dose patch. Use to manage menopause symptoms if you still have periods.
Comes as a continuous or sequential tablet, depending on whether you're still having periods.
Oestrogen-only HRT to tackle vaginal menopause symptoms.
HRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.
Oestrogen only tablet or patch for women who've had a hysterectomy, or used alongside a progesterone in combined HRT.
Generic version of Livial. Hormone-free HRT that can improve mood and libido.
The natural progesterone treatment. Taken alongside oestrogen to relieve symptoms of menopause.
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Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
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