Low-dose combined HRT, good for hormone sensitivity.

Premique is a combined hormone replacement therapy (HRT) treatment for post-menopausal women. It reduces menopause symptoms and can help to prevent osteoporosis in a once daily tablet.
Answer a few questions about your health, and we’ll recommend HRT treatments tailored just for you. Order Premique online and get your medication on subscription.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Taking Premique is quick and easy. Swallow one pill each day with or without food and water. Don’t skip any pills and don’t pause in between packs.
If you aren’t currently taking any HRT medications, you can begin taking Premique at any time. If you’re making the switch from another continuous combined HRT option, you can also start at any time. However, if you’re switching from a different kind of HRT, you will need to start Premique after completing your last cycle.
If you miss a dose of Premique, take it as soon as you remember. If you missed more than one dose, only take the most recently forgotten one before continuing as usual. Never take a double dose.
Premique is proven to be an effective HRT treatment for post-menopausal women. It provides significant health benefits while causing fewer side effects than higher dose HRT options .
There are two different doses available for Premique. If you’re taking HRT for the first time, our clinician will start you on the low dose option with 0.3mg of conjugated estrogens and 1.5mg of medroxyprogesterone acetate.
If you are still experiencing menopause symptoms that are interfering with your daily life, our clinician may bump you up to the higher dose with 0.625mg of conjugated estrogens and 5mg of medroxyprogesterone acetate.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
A cost-utility analysis of low-dose hormone replacement therapy in postmenopausal women with an intact uterus. Current Medical Research and Opinion, 21(12), pp.2051–2061.
Weight gain and hormone replacement therapy: are women’s fears justified? Maturitas, 34, pp.S3–S8.
Good service
Excellent service from Treated, would highly recommend
Great service.
Great service.
Registered with GMC (No. 4624794)
Meet DanielRegistered with GPhC (No. 2202465)
Meet SanjedaRegistered with GPhC (No. 2070724)
Meet CraigRegistered with GPhC (No. 2070338)
Meet RuaraidhDelivery, consultation, treatment. It’s all included in the price.
We know health, but you know you.
Our experts tell you what’s safe, but you decide what’s best.
Answer a few questions and tell us about yourself. Get tailored advice from our clinicians so you can choose better.
Choose your treatment and how often you have it delivered.
We know things change. It’s the nature of life. We’ll check in regularly to make sure your treatment is still right for you.
Pause. Change. Skip. Start again. Any time you like.
Excellent
Very quick and efficient
Good service
Easy and efficient
Quick delivery and well packed , email to see how you are getting on . Cery pleased and highly recommend
Great company, fast delivery
Our average rating based on 15979 reviews.
Menopause (HRT): Here are some other options.
Oestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.
Simple treatment for menopause symptoms. Estradot is a HRT patch you change just twice a week.
Sequential dose patch. Use to manage menopause symptoms if you still have periods.
Continuous combined HRT pill. Made for menopause symptoms if you haven't had a period in 1 year.
Like Kliofem, but half the dose. HRT pill that’s good if you're sensitive to hormones.
A daily tablet for post-menopausal symptoms. It’s hormone-free, but works just like female hormones.
HRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.
Combined treatment for menopause relief. Sequential pills for women who no longer have periods.
Oestrogen-only pill for menopause treatment. Same hormones as Elleste Solo, different brand.
We're making healthcare more about you. Sign up to our newsletter for personalised health articles that make a difference.
Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
We couldn't find what you're looking for.
Here's everything we treat. Or, if you're looking for something we don't have yet, you can suggest something.
If there’s a particular treatment or condition you’re looking for, tell us and we’ll look into it for you.
If you made a mistake on the gender selection, you can amend this by pressing 'Cancel' below and changing your gender. If you entered the correct gender but made a mistake on the treatment category selection, you can choose a different category by pressing 'Choose other treatment' below.
You have recently requested a change to your treatment plan which is under review.
We'll let you know once our clinician has reviewed your request.
Our prescriber has already made treatment suggestions for you
You can view and select an option from your account.
You already have treatment for under review.
You have a consultation being reviewed. Our prescriber will contact you soon.
You already have a treatment plan for on pause. You can restart or make changes to this from your account.
Submit your question here, or tell us if you’ve found an issue on our site.
We’ll get back to you very soon. We aim to respond to all queries in one working day.
You’re signed up to our newsletter. Keep an eye on your inbox for our latest update.
By clicking 'Subscribe now' you're agreeing to our Privacy Policy.
Your order is on hold because we need to verify your identity.
You have an order on hold because we couldn’t take your payment. To continue, please add a new payment method.