HRT pill in a neat calendar pack.
Trisequens
Estradiol/Norethisterone
Starting from £43.95
Starting from £43.95
Here’s what's included in the price:
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Buy Trisequens online.
Trisequens is a combination hormone replacement therapy medication that is used to treat postmenopausal symptoms like hot flushes and prevent osteoporosis.
Talk to an expert and get tailored treatment recommendations. With Treated, you can order Trisequens online and receive your prescription the next day.
Starting from £43.95
Here’s what's included in the price:
Consultation
Answer a few questions about your health so we can get to know you better.
Free 24h delivery
Your treatment delivered in secure packaging, the very next day.
Aftercare
We’ll check in with you regularly to see how your treatment is going.
Trisequens Estradiol/Norethisterone
What is Trisequens?
Menopause is caused by low levels of oestrogen and progesterone in women. These low hormone levels cause a variety of symptoms in postmenopausal women including hot flushes, night sweats and an increased risk of osteoporosis. Trisequens is a hormone replacement therapy treatment used to reduce these symptoms.
Trisequens combines estradiol with norethisterone acetate in a hormone replacement therapy treatment with a 28-day cycle. Estradiol is identical to the estrogen that is naturally produced in your body. Norethisterone acetate is a synthetic progestogen that closely mimics the progesterone that is naturally occurring in your body. Together, these hormones work to increase your hormone levels to reduce or eliminate your postmenopausal symptoms.
How does Trisequens work?
Trisequens comes in 28-day cycles. It’s a cyclical or sequential HRT product. The oestrogen is dosed continuously (daily) but in two different dosages. The progestogen is only added for 10 days of every 28-day cycle.
The hormones in Trisequens increase the oestrogen and progesterone in your body. This reduces the symptoms associated with menopause. It also reduces the risk of osteoporosis, which can cause brittle bones.
Who is Trisequens for?
Trisequens is a sequential combined pill for hormone replacement therapy. It is often prescribed for postmenopausal women who have symptoms of the menopause but still have irregular bleeding. It’s not an appropriate treatment for women who have a history of certain cancers, blood clots, heart attack, stroke or liver disease. If you have porphyria or an allergy to any ingredients in Trisequens, you shouldn’t take it.
This page was medically reviewed by Dr Daniel Atkinson, GP Clinical Lead on August 02, 2022. Next review due on August 01, 2024.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Trisequens Estradiol/Norethisterone
How to use Trisequens
Treating menopause symptoms with Trisequens is straightforward. It comes in 28-day pill packs that should be taken in order. Take your pill around the same time each day with a glass of water.
If you miss a dose of Trisequens, take it within 12 hours. If more than 12 hours have gone by, resume your pills the next day. Never take a double dose to make up for a missed dose. If you take more Trisequens than you’re supposed to, contact your doctor for guidance.
Don’t stop taking Trisequens without talking to your doctor first. They will advise you about the effects of discontinuing treatment and discuss other treatment options for you.
Trisequens reviews
Women who take Trisequens often experience reduced postmenopausal symptoms. This sequential hormone replacement therapy treatment is as effective as continuous hormone therapy replacement options .
What dose of Trisequens is best for me?
Trisequens isn’t available in different doses. It contains 2mg of estradiol and 1mg of norethisterone acetate in each pill. Taking your Trisequens at the same time each day maintains your hormones levels to reduce or prevent postmenopausal symptoms.
This page was medically reviewed by Dr Daniel Atkinson, GP Clinical Lead on August 02, 2022. Next review due on August 01, 2024.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Reference Popover #ref1
Treated trusted source
Comparison of continuous and sequential oestrogen-progestogen treatment in women with climacteric symptoms. (1989). Maturitas, 11(1), pp.75–82.
This page was medically reviewed by Dr Daniel Atkinson, GP Clinical Lead on August 02, 2022. Next review due on August 01, 2024.
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Delivery, consultation, treatment. It’s all included in the price.
Trisequens Estradiol/Norethisterone
- 2mg/1mg
| Quantity | Starting from |
|---|---|
| 84 Tablets | £43.95 |
| 168 Tablets | £73.95 Save £13.95 |
Elleste Solo Estradiol
- 1mg
- 2mg
| Quantity | Starting from |
|---|---|
| 84 Tablets | £39.95 |
| 168 Tablets | £63.95 Save £15.95 |
| Quantity | Starting from |
|---|---|
| 84 Tablets | £39.95 |
| 168 Tablets | £63.95 Save £15.95 |
Evorel Conti Estradiol/Norethisterone
- 50mcg/170mcg/24hr
| Quantity | Starting from |
|---|---|
| 8 Patches | £47.95 |
| 24 Patches | £87.95 Save £55.90 |
Evorel Sequi Estradiol/Norethisterone
- 50mcg/24hr; 50mcg/170mcg/24hr
| Quantity | Starting from |
|---|---|
| 8 Patches | £47.95 |
| 24 Patches | £87.95 Save £55.90 |
Femoston Estradiol/Dydrogesterone
- 1mg/10mg
- 2mg/10mg
| Quantity | Starting from |
|---|---|
| 84 Tablets | £51.95 |
| 168 Tablets | £87.95 Save £15.95 |
| Quantity | Starting from |
|---|---|
| 84 Tablets | £51.95 |
| 168 Tablets | £87.95 Save £15.95 |
Gina Estradiol
- 10mcg
| Quantity | Starting from |
|---|---|
| 24 Tablets | £58.95 |
| 48 Tablets | £98.95 Save £18.95 |
Oestrogel Estradiol
- 0.06%
| Quantity | Starting from |
|---|---|
| 80 Gel | £35.95 |
| 160 Gel | £49.95 Save £21.95 |
| 240 Gel | £61.95 Save £45.90 |
Progynova Estradiol
- 50 mcg/24hrs
- 100mcg/24hrs
- 1mg
- 2mg
| Quantity | Starting from |
|---|---|
| 12 Patches | £55.95 |
| Quantity | Starting from |
|---|---|
| 12 Patches | £55.95 |
| Quantity | Starting from |
|---|---|
| 84 Tablets | £37.95 |
| 168 Tablets | £59.95 Save £15.95 |
| Quantity | Starting from |
|---|---|
| 84 Tablets | £37.95 |
| 168 Tablets | £59.95 Save £15.95 |
Tibolone Tibolone
- 2.5mg
| Quantity | Starting from |
|---|---|
| 28 Tablets | £33.95 |
| 56 Tablets | £47.95 Save £19.95 |
| 84 Tablets | £61.95 Save £39.90 |
Utrogestan Micronised progesterone
- 100mg
| Quantity | Starting from |
|---|---|
| 30 Tablets | £37.95 |
| 60 Tablets | £59.95 Save £15.95 |
| 90 Tablets | £81.95 Save £31.90 |
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Similar but different.
Menopause (HRT): Here are some other options.
Elleste Solo
EstradiolOestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.
- Starting from £39.95
- Form Tablet
- Available doses 1mg; 2mg
- Active ingredient Estradiol
- Prices starting at £39.95
Evorel Conti
Estradiol/NorethisteroneCombined continuous HRT patch. Used it's been more than 12 months since your last period.
- Starting from £47.95
- Form Skin patch
- Available doses 50mcg/170mcg/24hr
- Active ingredient Estradiol/norethisterone
- Prices starting at £47.95
Evorel Sequi
Estradiol/NorethisteroneSequential dose patch. Use to manage menopause symptoms if you still have periods.
- Starting from £47.95
- Form Skin patch
- Available doses 50mcg/24hr; 50mcg/170mcg/24hr
- Active ingredient Estradiol/norethisterone
- Prices starting at £47.95
Femoston
Estradiol/DydrogesteroneComes as a continuous or sequential tablet, depending on whether you're still having periods.
- Starting from £51.95
- Form Tablet
- Available doses 1mg/10mg; 2mg/10mg
- Active ingredient Estradiol/dydrogesterone
- Prices starting at £51.95
Gina
EstradiolOestrogen-only HRT to tackle vaginal menopause symptoms.
- Starting from £58.95
- Form Vaginal tablet
- Available doses 10mcg
- Active ingredient Estradiol
- Prices starting at £58.95
Oestrogel
EstradiolHRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.
- Starting from £35.95
- Form Gel
- Available doses 0.06%
- Active ingredient Estradiol
- Prices starting at £35.95
Progynova
EstradiolOestrogen only tablet or patch for women who've had a hysterectomy, or used alongside a progesterone in combined HRT.
- Starting from £37.95
- Form Tablet
- Available doses 1mg; 2mg
- Active ingredient Estradiol
- Prices starting at £37.95
Tibolone
TiboloneGeneric version of Livial. Hormone-free HRT that can improve mood and libido.
- Starting from £33.95
- Form Tablet
- Available doses 2.5mg
- Active ingredient Tibolone
- Prices starting at £33.95
Utrogestan
Micronised progesteroneThe natural progesterone treatment. Taken alongside oestrogen to relieve symptoms of menopause.
- Starting from £37.95
- Form Capsule; pessary
- Available doses 100mg; 200mg
- Active ingredient Progesterone
- Prices starting at £37.95
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Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
