A pyogenic granuloma is a small, harmless growth that appears on the skin. It appears as an overgrowth of tiny blood vessels that form a pink, red, or purple bump. These bumps are quite small, usually not larger than 1cm across. Although it may look concerning, it’s not a type of cancer, it’s not contagious and doesn’t result from an infection.
Pyogenic granulomas are often found on the hand, fingers or face. They can be fragile and may ooze and bleed if touched. These raised and moist bumps are usually painless but can cause inflammation in the surrounding skin.
They have many names including lobular capillary haemangioma. They’re also known as granuloma gravidarum or pregnancy tumour when they happen during pregnancy.[1]
Where do pyogenic granulomas appear?
Pyogenic granulomas often show up on the fingers and face. Oral pyogenic granulomas appear inside the mouth and appear as bumps on the lips or gums (gingiva). These bumps can vary in size and may have a yellowish, pink or red colour.
They can also be found in other places like the eyes, nose and scalp. Ocular (of the eyes) pyogenic granulomas can affect the eyelid or the conjunctiva (the thin tissue that covers the white part of the eye and the inner surface of the eyelids).
Who gets pyogenic granulomas?
Pyogenic granulomas can affect people of any age, race or gender. They are more commonly seen in children around 6 years old, teenagers, young adults and pregnant people. During pregnancy, they are often referred to as granuloma gravidarum, granuloma of pregnancy, or epulis gravidarum.
More men than women tend to get pyogenic granulomas (out of every five people who get them, three will be male). However, oral pyogenic granulomas are more common in women during pregnancy or when using birth control pills.[2]
How common are pyogenic granulomas?
Pyogenic granulomas are fairly common, particularly in pregnant women. But it’s difficult to know exactly how many cases there are because many people don’t report them.
This page was written by The Treated Content Team.
This page was medically reviewed by Mr Craig Marsh on December 05, 2023. Next review due on December 05, 2026.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Pyogenic granuloma
What causes pyogenic granulomas?
We’re not exactly sure what causes pyogenic granulomas. However, doctors have noticed that they can happen after minor injuries or irritation. Nasal piercings, for instance, can cause pyogenic granulomas in the nose. Some cases have also been linked to hormonal changes, such as when taking birth control pills or during pregnancy.
Infections with Staphylococcus aureus, a type of bacteria, can also be linked to pyogenic granulomas. And sometimes poor oral hygiene can lead to Staphylococcus aureus infections in the mouth.
And lastly, certain medications have been associated with pyogenic granulomas, too. These include some medicines used for HIV/AIDS, cancer treatments, and drugs that weaken the immune system.[1]
What are the symptoms of a pyogenic granuloma?
Pyogenic granulomas are skin bumps that can appear in different colours like pink, red or purple. They grow quickly, starting from a few millimetres (the tip of a pencil), but usually reaching no more than 1cm (about half an inch). Some people describe them as looking like ground beef. And sometimes they have a scaly, white ring at the bottom.
Usually you only have one, but sometimes there can be more. As they grow, they can be attached to the skin by a stalk-like structure (in which case they’re called pedunculated) or they can grow directly on the skin (when they’re called sessile). The main problem with pyogenic granulomas is that they can ooze and bleed, but they don’t usually cause pain.[2]
Can pyogenic granulomas lead to other problems?
Pyogenic granulomas are harmless bumps made of tiny blood vessels on the skin. They’re not cancerous and don’t cause any long-term problems.
This page was written by The Treated Content Team.
This page was medically reviewed by Mr Craig Marsh on December 05, 2023. Next review due on December 05, 2026.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Pyogenic granuloma
What treatment options are there for pyogenic granulomas?
Treatment options for pyogenic granulomas usually involve using creams, gels, powders, or eye drops on the affected areas, or more invasive procedures.
Topical treatments that are applied directly to the skin to treat pyogenic granulomas include:
Imiquimod skin cream.
Eye drops (containing phenols like timolol) if the granuloma is in the eye.
Chemicals like silver nitrate, timolol and trichloroacetic acid (TCA) — used to “burn” the granuloma.
Steroid injections into the bump.
Procedures that can remove granulomas include:
Freezing it off with cryotherapy.
Scraping it off with curettage and sealing the skin with heat (cautery).
Using laser treatment to destroy the abnormal tissue.
Surgery to cut out the granuloma from the skin.
Is there a ‘best’ treatment for a pyogenic granuloma?
There is no one-size-fits-all treatment for pyogenic granulomas. It depends on what works well for you. Our clinicians will suggest bespoke treatment options that suit your preferences. Treatment recommendations will also vary depending on how severe your condition is.
As a rule of thumb, topical medications are usually effective and cause less scarring compared to surgery. So, they are generally the first choice when treating pyogenic granulomas. But remember, it’s important to listen to your doctor’s advice about which treatment is best for you.
Do pyogenic granulomas always need treatment?
In most cases, it’s necessary to treat pyogenic granulomas to make sure they go away completely. However, smaller ones might get smaller and fade away on their own over time, without needing any treatment.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Pyogenic granuloma
FAQ: Pyogenic granuloma
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
How are pyogenic granulomas diagnosed?
Answer:
Your doctor can usually diagnose a pyogenic granuloma just by looking at it. Sometimes, they might need to do a biopsy, which involves taking a small sample of the affected skin area for further testing. This is also to make sure that it's not something more serious like cancer.
Can a pyogenic granuloma be cancerous?
Answer:
Pyogenic granuloma is a benign growth on the skin, so it's not cancerous. But it's still important to have a doctor check it out to be sure it's not something more serious. Sometimes it can look similar to certain types of skin cancers, like amelanotic melanomas.
Can you get side effects from pyogenic granuloma medication?
Answer:
All treatments can cause side effects, and so can medications for pyogenic granuloma. But don't worry, most of the unwanted effects are mild and usually only happen around the area where the treatment is applied.
For example, you might feel a burning sensation, itchiness, or some pain after using the treatment. There might also be some scarring or changes in the colour of your skin. Silver nitrate can sometimes make the treated area look grey or blue-black. If you use timolol eye drops, your eyelids might swell, your eye could have some discharge or you might feel a burning or stinging sensation. Imiquimod can decrease your body’s ability to fight diseases. And so on.
For a full list of possible side effects, always read the leaflet that comes with your treatment.
Do pyogenic granuloma treatments always work?
Answer:
All treatments for pyogenic granuloma have been tested in clinical trials and been proven to work well. The success rate may vary depending on how severe your condition is, but most people find that it can be easily managed and treated.
However, sometimes pyogenic granulomas can come back in the same area in about 10%-15% of cases. This means that there's a chance you might have multiple new bumps (satellite lesions) around the original one.[1] But don’t worry, it’s nothing serious and there are plenty of medications or procedures available to treat the new bumps.
Treated trusted sources:
Folpe, A.L. (2009). Soft-Tissue Tumors of the Head and Neck, in Gnepp DR (ed) Diagnostic Surgical Pathology of the Head and Neck (Second Edition). Philadelphia, PA: Saunders Elsevier, pp.647–727.
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Dec 04, 2023
Published by: The Treated Content Team.Medically reviewed by: Mr Craig Marsh, Independent Prescriber
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
Mr Craig Marsh
Independent Prescriber
Craig is a pharmacist who’s also qualified to prescribe, which means he’s a bit of an expert on which medicines work best in any given situation. He consults with patients first hand, and also does a lot of work researching new and existing medications for the conditions we treat. Registered with the GPhC (No 2070724).
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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