Solifenacin
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Reviewed on June 27, 2023. by
Dr Daniel Atkinson
GP Clinical Lead
Registered with GMC (No. 4624794)
Next review due on
June 26, 2025.
Dr Daniel Atkinson

Product info

  • Solifenacin treats overactive bladder, reducing frequent urination, urgency, and leaks.

  • It works by relaxing bladder muscles, allowing for better bladder control.

  • It’s available in 5mg and 10mg tablets.

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£24.95
  • Prices include:
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  • Consultation + Access to our clinicians

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Solifenacin Solifenacin

What Is Solifenacin?

Solifenacin tablets are used to treat an overactive bladder, which can cause urinary incontinence. The tablets contain the active ingredient solifenacin succinate. They’re a type of medicine called antimuscarinics, which are a kind of anticholinergic.

An overactive bladder (OAB) isn’t a disease – it’s a collection of urinary symptoms. The most common symptom you’re likely to experience is a sudden, uncontrollable urge to use the bathroom. If you also leak urine when you get this urge, it’s called urinary incontinence. The two are different, but can be linked.

How does Solifenacin work?

Antimuscarinics like Solifenacin work by preventing a neurotransmitter called acetylcholine from binding itself to the M2 and M3 muscarinic receptors.[1] These receptors are responsible for contracting the bladder during urination, and blocking them should help keep your overactive bladder under control.[2]

What doses of Solifenacin are there?

There are two different Solifenacin doses: Solifenacin 5 mg tablets and Solifenacin 10 mg tablets. You’ll usually start by taking Solifenacin 5 mg tablets, and only move to 10 mg if your doctor tells you to. Taking the lowest dose of Solifenacin that keeps your bladder under control will minimise any risk of side effects.

Treated trusted sources:

  1. Staskin, D.R., MacDiarmid, S.A. (2006) Using anticholinergics to treat overactive bladder: the issue of treatment tolerability. The American Journal of Medicine. vol. 119, no 3. pp. 9-15.
  2. Hedge, S.S., et al. (1997) Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo. British Journal of Pharmacology. vol. 120, no. 8. pp. 1409-1418.
  3. EMC (2019). Package leaflet: Information for the user. Solifenacin 5 mg film-coated tablets, Solifenacin 10 mg film-coated tablets: Solifenacin succinate.
treated.com This page was written by The Treated Content Team.
Dr Daniel Atkinson
This page was medically reviewed by Dr Daniel Atkinson on June 27, 2023. Next review due on June 26, 2025.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Solifenacin Solifenacin

How to take Solifenacin

You should only take Solifenacin exactly as your clinician has instructed you to. Take one tablet of your prescribed dose once a day, swallowing it with a drink of water. You can take Solifenacin with or without food – whichever works best for you. Just make sure not to crush or chew the tablet when you take it.[1]

How long does it take Solifenacin to work?

Solifenacin reaches its peak in your bloodstream between three and eight hours after you take your tablet.[2] But Solifenacin is a medicine you’ll need to take long-term to keep your symptoms in check. It can take up to four weeks for you to feel its full effects.[3]

What should I do if I make a mistake taking Solifenacin?

If you forget to take a dose of Solifenacin, you can just take your missed dose as soon as you remember. The only exception is if it’s almost time to take your next one – in this case, just skip the one you missed and continue as normal from your upcoming dose.

If you accidentally take too much Solifenacin, you should contact a doctor or pharmacist as soon as possible. You could get symptoms like:

  • Dry mouth;
  • Dizziness;
  • Drowsiness;
  • Blurred vision;
  • Hallucinations;
  • Overexcitability;
  • Seizures;
  • Difficulty breathing;
  • Elevated heart rate;
  • Retaining urine in the bladder;
  • Dilated pupils.

Treated trusted sources:

  1. Basra, R. (2008) A review of solifenacin in the treatment of urinary incontinence. Therapeutics and Clinical Risk Management. vol. 4, no. 1. pp. 117-128.
  2. NHS (2021). Solifenacin.
  3. Athanasopoulos A., Giannitsas L. (2011). An overview of the clinical use of antimuscarinics in the treatment of overactive bladder. Advances in Urology.
treated.com This page was written by The Treated Content Team.
Dr Daniel Atkinson
This page was medically reviewed by Dr Daniel Atkinson on June 27, 2023. Next review due on June 26, 2025.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Solifenacin Solifenacin

Solifenacin isn’t suitable for everyone, and there are some things that you need to be aware of when taking it.

Here’s all the official info on it. If anything is unclear, let our clinician know, and they can talk with you about it.

Solifenacin Solifenacin

FAQ: Solifenacin

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

How effective is Solifenacin?

Answer:
Solifenacin has proven to be an effective treatment for an overactive bladder in clinical studies. In one trial, 503 people were given Solifenacin starting at 5mg (which could be increased to 10mg if needed), and 206 were given placebo. Those on Solifenacin found that they needed to urinate less frequently, urgently, and had fewer urge incontinence leaks when compared with those on placebo. Urgency bother was also reduced by 42.4%, and there was an increased level of treatment satisfaction on Solifenacin.[1]

Does Solifenacin cause weight gain?

Answer:
Solifenacin shouldn’t cause you to gain any weight. However, there’s a small chance it can make you feel less hungry – which can cause weight loss. If you’re worried about your weight while taking Solifenacin, speak with your clinician.

Can you get Solifenacin side effects?

Answer:
There’s a chance you can get some Solifenacin side effects, the same as with any medicine. But they don’t affect everyone. 

There have been reports of angioedema, a skin allergy that causes swelling in the tissue below the skin’s surface, that can also obstruct breathing. If you get any of these symptoms, stop using Solifenacin straight away and get medical attention. Likewise, if you have any kind of allergy attack or skin reaction, speak to your doctor or pharmacist immediately.

The most common side effects of Solifenacin are:

  • dry mouth;

  • blurred Vision;

  • constipation;

  • nausea; and:

  • indigestion, abdominal pain, burping, and heartburn.


If you want a full list of Solifenacin side effects, take a look at the patient information leaflet.

Who is Solifenacin for?

Answer:
There are some Solifenacin warnings you should be aware of, because it isn’t suitable for everyone. If you’re wondering who shouldn’t take Solifenacin, speak to your doctor if you:

  • have had trouble emptying your bladder or passing urine;

  • have an obstruction of your digestive system (like constipation)

  • are at risk of your stomach and bowel movements slowing down;

  • have severe kidney disease;

  • have a hiatus hernia or heartburn; or:

  • have a nervous disorder (autonomic neuropathy).

Are there any alternatives to Solifenacin?

Answer:
If you’re looking for a treatment similar to Solifenacin, you can get other antimuscarinic treatments for an overactive bladder. These include:

  • Oxybutynin (also sold under the brands Ditropan, Lyrinel, and Kentera);

  • Tolterodine (also sold under the brand names Blerone, Detrol, Detrusitol, Inconex, Mariosea, Neditol, Preblacon, and Santizor); and:

  • Darifenacin (also sold under the brand name Emselex);


These all work in the same way as Solifenacin – but if you get side effects on one type of antimuscarinic, switching to a different one could help. While there is a small difference in how well these different treatments have performed in clinical trials, it isn’t enough to affect how they work in practice; many clinicians consider them all comparable in terms of how effective they are.[popover id=ref6]

Treated trusted sources:

  1. Basra, R., Kelleher, C. (2008). A review of solifenacin in the treatment of urinary incontinence. Therapeutics and Clinical Risk Management. vol. 4, no. 1. pp. 117-128.

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Dr Daniel Atkinson

GP Clinical Lead
Dr Daniel Atkinson

Registered with GMC (No. 4624794)

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Solifenacin
4.0

Average rating based on 4 reviews.

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551

Great delivery medication workes

K
551

Excellent service and product

I have since the menopause had a problem with urge incontinence . I take one of these every morning and it helps so much .. would highly r recommend 👍🏻😊

L

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