Imvaggis is a vaginal HRT that treats symptoms like vaginal dryness. When your oestrogen levels decrease during menopause, your vagina can feel irritated, dry and painful.
And that’s where vaginal oestrogen like Imvaggis comes in. To order Imvaggis, simply answer a few questions online, and we’ll recommend personalised treatments just for you.
Starting from£53.95
Here’s what's included in the price:
Consultation
Answer a few questions about your health so we can get to know you better.
Free 24h delivery
Your treatment delivered in secure packaging, the very next day.
Aftercare
We’ll check in with you regularly to see how your treatment is going.
Imvaggis is a treatment for vaginal symptoms of menopause, such as dryness and irritation. It works locally to increase oestrogen levels in your vagina. Vaginal dryness can affect both menopausal and non-menopausal women, but it’s most commonly seen during and after menopause. This is because it’s usually caused by decreased oestrogen levels, which happens during menopause, but other factors like dehydration, lack of blood flow to the vaginal walls, and stress also contribute to it.
Vaginal dryness is mainly treated using hormonal treatments. However, hormonal medication is only a temporary fix. Once you stop using it, your symptoms will return unless your body starts to produce more oestrogen.
How does Imvaggis work?
Imvaggis contains estriol, a synthetic version of oestrogen. It's ‘bioidentical’ to the oestrogen naturally produced by your body. Bioidentical hormones have proven to be more effective than non-bioidentical ones.
Vaginal dryness is often caused by an oestrogen deficiency. So by increasing the amount of oestrogen in your vagina, Imvaggis can help moisten it, maintain its lining and retain its elasticity. It can also help prevent infection by restoring and maintaining vaginal pH, which helps to reduce bacterial growth and urinary tract infections.
What doses of Imvaggis are there?
There’s only a 0.03mg dose of Imvaggis available. It's used daily for three weeks, followed by twice a week till the end of the treatment course.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
ImvaggisEstriol
How to use Imvaggis
Imvaggis contains the hormone estriol, which is administered through a dissolvable pessary inserted into your vagina. To use Imvaggis, follow the instructions below:
Wash your hands and get into a comfortable position. This will make it easier to insert the pessary into your vagina. You can stand up or lie down, whatever’s most comfortable for you.
Remove the pessary from the foil pack.
Insert the pessary into your vagina as far as you can.
Repeat the steps daily, preferably in the evening before bedtime, for three weeks. After three weeks, insert one pessary twice a week.
How long does Imvaggis take to work?
Imvaggis starts to work within a couple of hours, but it’ll probably take a few weeks to months to see the full effects. It's important to keep using it, even if your symptoms improve. Usually symptoms come back once you stop using hormonal treatment, to help with this, your clinician may gradually reduce the dosage for you.
What should I do if I make a mistake when using Imvaggis?
If you accidentally use too many pessaries, don't panic. While you may experience vaginal bleeding for a few days or feel sick, it won't cause any serious health complications. However, it's best to still phone a doctor for advice.
If you forget to use Imvaggis during the first three weeks (during daily use), skip the missed dose. Don’t use a double dose to make up for a missed one. But if you miss a dose after three weeks (when it’s used bi-weekly), use it another day instead.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
ImvaggisEstriol
ImvaggisEstriol
FAQ: Imvaggis
Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.
What are the alternatives to Imvaggis?
Answer:
If, for whatever reason, Imvaggis isn’t suitable for you, you’ve still got a lot of options to choose from. Similar treatments to Imvaggis include Gynest and Ovestin. Both contain the same active ingredient as Imvaggis but at a higher concentration. Gynest and Ovestin are applied using a removable applicator, which is filled with cream and inserted into your vagina, where it is applied.
But if you prefer not to use hormone therapy, Replens vaginal moisturiser may be a suitable alternative. It doesn't contain any hormones, instead it contains moisturising ingredients like polycarbophil, glycerin and mineral oil to help lubricate your vagina. It's a fast-acting lubricant, providing instant relief from dryness which can last up to three days.
How effective is Imvaggis?
Answer:
A very low dose of estriol (the active ingredient in Imvaggis) was evaluated to see if it was an effective treatment for menopausal women suffering from vaginal dryness. The study involved 61 women, 50 of which used 0.005% estriol and the other 11 had a placebo for 12 weeks.
At the end of the trial, estriol was shown to be an effective treatment for vaginal dryness. The patients experienced a significant decrease in genital pain, itching and vaginal dryness. However, although the study showed it was an effective treatment, the sample size of the group was small. Therefore, the results may not be reflective of a larger population.
Can I use Imvaggis during menopause?
Answer:
Yes, Imvaggis is suitable to use during menopause and is an effective treatment to help provide relief of vaginal menopausal symptoms. As women age, they enter a menopausal transition in which they stop having periods. As a result, their body produces less of the hormone oestrogen. This causes symptoms like hot flashes, mood changes and vaginal dryness. To ease the symptoms of menopause, hormone replacement therapy (HRT) is commonly used. But if you only suffer from vaginal dryness, or you’d rather not use systemic (full-body) HRT, Imvaggis may be an ideal treatment for you.
What are the side effects of Imvaggis?
Answer:
Imvaggis is a ‘local’ HRT, meaning it only affects the vagina. Even if it enters your bloodstream, it won’t have the same risks as oral HRT as it's a lower dose. However, like all medicines, there are some side effects which might affect you. These include:
vaginal burning
vaginal itching and irritation
discomfort when urinating
vaginal discharge
anorectal (bottom) discomfort
If you find the side effects are uncomfortable or unpleasant, you can message our clinician online, and they’ll help you decide how to manage them. They might also provide you with an alternative treatment option with fewer side effects.
Why should I buy Imvaggis with Treated?
Answer:
We make treating vaginal dryness easy and comfortable. Simply answer a few questions about your health, and we’ll recommend treatments tailored to you. After choosing your preferred treatment, we’ll deliver them the next working day.
Our clinicians will also check in with you throughout your treatment journey to see how you’re getting on, and if you have any questions for them, they'll be happy to help you out.
Efficacy and safety of ultra-low dose 0.005% estriol vaginal gel for the treatment of vulvovaginal atrophy in postmenopausal women with early breast cancer treated with nonsteroidal aromatase inhibitors: A phase II, randomized, double-blind, placebo-controlled trial. 27(5), 526-534.
Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
