Plaobes®

What is Plaobes?

Plaobes is a weight loss treatment in a pen. It’s a type of glucagon-like peptide-1 receptor agonist, or GLP-1, which works by mimicking your body’s natural hunger hormones to help control your appetite.

You inject Plaobes once daily. You usually start on the lowest daily dose (0.6mg), and work up through the available doses each week until you reach the 3mg maintenance dose.

Unlike some other weight loss injections, the pens all contain the same amount of medicine – you’ll set the dose you need with a selector switch on the pen itself.

How does Plaobes work?

Glucagon-like peptide-1 receptor agonists work by mimicking your body’s natural GLP-1 hormone, which plays a vital role in managing your hunger and digestion. It’s released when you eat.

By mimicking this hormone, Plaobes reduces your appetite and increases feelings of fullness, as well as slowing down the rate food leaves your stomach. This means that you won’t feel the need to eat as much, making it easier to create the calorie deficit needed to steadily lose weight.

What doses of Plaobes are there?

Plaobes pens are pre-filled. Each pen contains 18mg of liraglutide in 3ml.

The five doses of Plaobes are: 0.6mg, 1.2mg, 1.8mg, 2.4mg, and 3mg.

You’ll usually start on the lowest dose, and change your dose every week until you start using 3mg each day, which you’ll remain on for the rest of your treatment plan.

Moving up through the doses this way means your body has time to adapt to the medication, and can reduce the chances of side effects developing.

How long does Plaobes take to work?

Weight loss doesn’t always follow a linear path, so there’s no guarantees of how quickly Plaobes will work. But GLP-1s have been shown to work effectively at helping people balance their blood sugar and lose weight¹ when used alongside a calorie-controlled diet and regular physical activity.

Liraglutide, the active ingredient in Plaobes, has been shown to work effectively for weight loss.

In one study, 64.1% of patients lost at least 5% of their starting weight after 6 months, and 34.5 had lost at least 10%.² In another trial of patients using liraglutide over a 56-week period, 63.2% had lost at least 5% of their starting weight.³

How to take Plaobes

You’ll need to take Plaobes each day, ideally at the same time, to help you stick to a dosage routine and avoid missing doses.

• Remove the outer cap from the pen.
• Turn the dose counter until you see your dose.
• Insert the needle into your skin at an angle where you can still clearly see the dose counter.
• Press the dose button down until the counter reads 0.
• Keep the needle held in your skin while slowly counting to 6.
• Remove the needle from your skin.Dispose of the needle using a sharps bin.

The patient information leaflet that comes with your pen contains a detailed step-by-step guide to using your pen, which you should read before using Plaobes for the first time. Your clinician can also give you more guidance on how to use it, if you’re still not sure.