Wegovy

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Reviewed on Mar 18, 2025. by Dr Alexandra Cristina Cowell Writer & Clinical Content Reviewer Registered with GPhC (No. 2241935) Next review due on Mar 18, 2028.
Alexandra Cristina

Last updated on Sep 24, 2025.

What does Wegovy look like?

Wegovy is available in two forms: a pre-filled injection pen and an oral tablet.

Wegovy injections

Wegovy comes as a pre-filled injection pen with single-use needles. The Wegovy pens come in five preset dosages: 0.25mg, 0.5mg, 1mg, 1.7mg and 2.4mg, with each dose being a different colour. You’ll take one dose once a week.

A new Wegovy dose, 7.2mg, has been approved by the MHRA (the UK’s medicines regulator). It’s expected to be released in late 2026, but in the meantime you can take three 2.4mg doses if prescribed by your clinician.

Wegovy pills

The Wegovy pill is an oral tablet taken once daily. The pills are available in four strengths: 1.5mg, 4mg, 9mg and 25mg.

For both forms, the prescriber will outline the course of treatment and let you know which dosage you should be using and when. For the pill, patients generally start on 1.5mg daily for 30 days, before increasing to 4mg, 9mg, and eventually a maintenance dose of 25mg per day.

Wegovy pill vs injection comparison

Wegovy pill Wegovy injection
How to take it Once daily oral tablet Once weekly subcutaneous injection
Available doses 1.5mg, 4mg, 9mg and 25mg 0.25mg, 0.5mg, 1mg, 1.7mg, 2.4mg and 7.2mg
Effectiveness Average 17.7% weight loss over 64 weeks Average 15-21% weight loss over 68-72 weeks
Timing rules Must take on an empty stomach with max 120ml water. Wait 30 mins before eating/drinking Can be taken at any time of day, with or without meals

How should I store Wegovy?

Storing injections

Keep Wegovy pens in the original box refrigerated between 2°C to 8°C. This will help protect the medication from sunlight and stop it from deteriorating. If needed, Wegovy pens can be kept outside of the fridge at room temperature with the cap on for 28 days.

Don’t freeze the pens or keep them out in direct sunlight. If you accidentally leave the pens in these conditions, throw away the pens and don’t use them.

Storing pills

Wegovy pills should be stored in their original blister packaging at room temperature, away from moisture and direct sunlight. Keep them out of reach of children.

How does Wegovy work?

Wegovy contains the active ingredient semaglutide. Semaglutide is known as a GLP-1 receptor agonist, which means that it binds to the GLP-1 receptors in the brain involved with appetite regulation. This reduces the feelings of hunger and increases the feeling of fullness. This helps you eat less food, reducing your calorie intake and causing you to lose weight.

Alongside Wegovy, users should stick to a healthy lifestyle involving a calorie-deficit diet (typically around 1500 calories) and regular physical activity.

How fast does Wegovy work?​

Every person will react differently to Wegovy, so we can’t say how soon you’ll be able to start seeing results. But it is a highly effective treatment and users have reported noticing differences in their weight fairly early on during their treatment.

You might start to feel the effects of the treatment in the first few weeks, such as having a smaller appetite or not feeling as hungry. In the first month or so, you might also notice you’ve lost some weight.

Using a weight loss treatment like Wegovy does require some patience and dedication to the process. Don’t give up on your treatment within a couple of weeks or months. To see an actual difference you should use it long term. But, if you’ve been using it for a while and you’re not seeing any changes, message your clinician so they can decide what to do next.

Is Wegovy effective?

Is Wegovy effective?

Wegovy has been found to be a highly effective and well-tolerated treatment to aid weight loss in both injectable and pill forms.

In clinical trials I, II and III for the injection, 83.5%, 67.4% and 84.8% of participants taking Wegovy were found to experience a weight loss of at least five percent of their body weight.

For the oral pill, the Phase III OASIS-4 clinical trial demonstrated that participants taking the 25mg daily dose achieved an average weight loss of around 16.6% of their body weight over 64 weeks.

How long should I take Wegovy for?

It usually takes several months to build up to the full dose of Wegovy for weight loss. If the medication proves to be suitable, and produces good results for the patient, then they can continue to use it for as long as it remains beneficial. Whether that be for weight loss or weight maintenance.

Getting the best out of Wegovy

In order to get the best results out of Wegovy you should also adopt a reduced calorie diet, as well as a regular exercise regime. Opt for low-calorie dense foods like rice, oats and lentils. And eating whole fruits and vegetables can make you feel fuller for longer.

How to use Wegovy

Get to know your medication before you start taking it. Read the instructions that come with your Wegovy treatment.

How to use the Wegovy pill

Taking the pill correctly is essential for it to be absorbed properly by your body:

  • Take your Wegovy pill first thing in the morning, on an empty stomach.
  • Swallow the tablet whole with a small sip of plain water (no more than 120ml). Don’t crush or chew the tablet.
  • Wait at least 30 minutes before eating, drinking anything other than water, or taking any other oral medications. This gives the pill the best chance to work uninterrupted.

How to use the Wegovy injection

Each Wegovy pen is preset at one particular dose. Make sure you follow the dosage plan outlined by the prescriber and use the corresponding pen.

Things to do before using Wegovy:

  • Check that your pen is good for use. This means that there are no signs of damage or discolouration. 
  • Always wash your hands before you inject your medication. . 
  • You can use Wegovy on the top of the thighs, upper arm or stomach (keeping two inches away from the belly button.) Just make sure the injection site is free from bruising, damaged skin, scars or stretch marks. 
  • Don’t use the exact same injection site as the previous week.

How to use Wegovy:

  • Clean the injection site with an alcohol swab or water and soap. 
  • Remove the cap and look through the pen window to check that the medication is clear and colourless. If it looks cloudy or discoloured, don’t use it.

  • Get a new needle and check it for damages (if it’s damaged, don’t use it). Tear off the paper tab.

  • Push the needle straight onto the pen, turn until it’s tight.

  • The needle is covered by two caps, both of which you’ll need to remove. Pull off the outer needle cap first and leave it to one side — you’ll need to use it to safely remove the needle after injection.

  • Then, pull off the inner needle cap and throw it away. A drop of the medication might appear at the tip of the needle.

If it’s your first injection with a new pen, you’ll need to check the flow. To do this:

  • Turn the dose selector until the flow check symbol lines up with the dose pointer.
  • Then hold the pen with the needle pointing up and press and hold the dose button until the counter returns to 0.
  • A drop of Wegovy should appear at the needle tip when you do this. If it doesn’t, check the flow again by repeating this process.
  • If there is still no drop, change the needle and check the flow once more.
  • If a drop of Wegovy still doesn’t appear with a new needle, don’t use the pen.

Next:

  • Turn the dose selector until the dose counter stops at your prescribed dose.
  • Choose your injections site, and insert the needle into your skin.
  • Making sure not to cover the dose counter, press and hold down the dose button.
  • With the button held down, slowly count to 6. The 0 must line up with the dose pointer. You might feel or hear a click when this happens.
  • Remove the needle from your skin. If you notice bleeding at the site of the injection, then you can gently press it with a clean gauze pad or cotton ball.

After your injection:

  • Leaving the outer needle cap on a flat surface, guide the needle into the cap, making sure not to touch the cap or the needle.
  • Once the needle is covered, push the outer needle cap until it’s completely on.
  • Unscrew the needle and dispose of it carefully, either into a sharps bin or as directed by your clinician.
  • To avoid blocked needles, contamination, infection, or errors, always throw your needles away immediately after use. Never store your pen with the needle attached.
  • Return the cap to your pen, to protect the medication from light.
  • When the pen is empty (after four doses), dispose of it, without a needle on, as instructed by your clinician. Usually, the pen cap and empty carton can be added to your household waste.

Can you drink alcohol using Wegovy?

It’s a good idea to speak to your prescriber before you drink alcohol when using Wegovy. Alcohol can lower blood sugar levels, so if you have diabetes this could be problematic. Also, most alcoholic drinks are high in calories and might interfere with your reduced calorie diet.

What to do if I forget a Wegovy dose

For the injection: If you miss taking a dose of Wegovy and the next scheduled dose is more than two days away then you should take the missed dose. However, if you miss a dose and your regular upcoming dose is less than two days away then you shouldn’t take the missed dose. Instead wait for your regular day to continue treatment as usual.

For the pill: If you miss a daily dose of the Wegovy pill, skip the missed dose. Don’t take a double dose to make up for a forgotten one. Simply take your next dose at the usual time the following morning.

Where can I buy Wegovy?

You can buy Wegovy online by answering a few questions. Your clinician will then review your answers to make sure it’s safe and suitable for you to use. They’ll also provide you with more information on how to use it, lifestyle changes to make and anything extra.

If you want information on the price and how much it will cost you, please check this page for all the details.

Is Wegovy right for you?

Wegovy injections can help overweight and obese patients lose weight in a controlled and safe manner. A course of Wegovy should be used with a reduced calorie diet and increased exercise. 

If you think Wegovy could help you to improve your health — chat to a clinician. They’ll ask you about your health needs, preferences and history in order to make sure that it’s a safe and suitable treatment option for you.

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This page was medically reviewed by Dr Alexandra Cristina Cowell, Writer & Clinical Content Reviewer on Mar 18, 2025. Next review due on Mar 18, 2028.

Last updated on Sep 24, 2025.

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