Provera ®
Out of stock

Price checker

£51.95
  • Prices include:
    Express shipping

    24 hour shipping by secure courier.

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    £51.95
    Save £0.00 each order
Reviewed on Feb 19, 2026. by Dr Alexandra Cristina Cowell Writer & Clinical Content Reviewer Next review due on February 13, 2029.
Dr Alexandra Cristina Cowell

Last updated on Feb 19, 2026.

Product info

  • Provera was a progesterone tablet treatment for menopause symptoms.

  • It could be prescribed alongside oestrogen to ease hot flushes, fatigue and low libido.
  • It was discontinued in 2025, but replaced by the manufacturer with the generic Medroxyprogesterone.

Price checker

£51.95
  • Prices include:
    Express shipping

    24 hour shipping by secure courier.

  • Consultation + Access to our clinicians

    Ask our experts anything you like, any time you want.

  • Total
    £51.95
    Save £0.00 each order
Provera Medroxyprogesterone acetate

What is Provera?

Provera was a medication used in hormone replacement therapy (HRT) to help balance hormone levels in the body. It contains the active ingredient medroxyprogesterone acetate, a synthetic form of the female hormone progesterone. Progesterone is important for various functions in the female reproductive system, such as regulating the menstrual cycle and preparing the uterus for pregnancy.

In HRT, Provera was often prescribed to women who had reached menopause to protect the lining of the uterus. It could be used along with oestrogen to relieve symptoms of menopause like hot flushes, night sweats, vaginal dryness, low libido, and fatigue.

How does Provera work?

The active ingredient in Provera was medroxyprogesterone acetate, a type of medicine called a progestogen. Its job is to mimic the effects of the female hormone progesterone. It enters cells and attaches to a specific receptor, where it can work.[1]
It works by filling in for the hormones that drop during and after menopause. When you take oestrogen as part of your HRT, it can thicken the uterus lining, which may increase your risk of womb cancer. So taking a progestogen like Provera can counteract this effect and work together with the oestrogen to ease menopause symptoms.

What doses are available for Provera?

Provera was available in 2.5mg, 5mg and 10mg tablets. These dosages were used for menstrual issues, endometriosis, and menopause symptoms. It was also available in higher strengths of 100mg, 200mg and 400mg, but these were mainly prescribed for specific types of cancer.

Treated trusted sources:

  1.  Edwards, M. and Can, A.S. (2023). Progestin. StatPearls. Treasure Island (FL): StatPearls Publishing
treated.com This page was written by The Treated Content Team.
Dr Alexandra Cristina Cowell 1218322
This page was medically reviewed by Dr Alexandra Cristina Cowell on February 13, 2026. Next review due on February 13, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Provera Medroxyprogesterone acetate

How to use Provera

Depending on what stage of menopause you’re at, your clinician will prescribe you a dosing regimen that you should follow closely.

There were two ways to take Provera:

Sequentially:

  • The recommended dose was 10mg per day for 12 to 14 days of each cycle
  • Take it at the same time every day with your oestrogen
  • Swallow it whole with a glass of water.

Continually:

  • The recommended dose is 2.5mg to 5mg every day for 28 days of your cycle
  • Take it at the same time every day with your oestrogen
  • Swallow it whole with a glass of water.

How long does Provera take to work?

Provera was taken as part of a combined HRT regimen. The oestrogen part of your HRT is what works to improve symptoms like hot flushes, and you might notice an improvement with this within a few weeks, with full benefits seen after around 2-3 months. The Provera part worked alongside the oestrogen from day one to ensure the lining of your womb remained thin and healthy. [1]

What happens if I make a mistake using Provera?

If you forget to take Provera, take the tablet as soon as you remember, then carry on as normal. Don’t take a double dose to make up for a missed dose. If you take too many Provera tablets, seek urgent medical attention. If you stop taking Provera suddenly, it can cause your symptoms to come back, as well as breakthrough bleeding. It’s important to let your clinician know if you want to stop taking Provera or if you want to alter your dose.

Treated trusted sources:

  1.  The National Health Service (NHS). (2023). Medicines: Medroxyprogesterone tablets: Common questions.
treated.com This page was written by The Treated Content Team.
Dr Alexandra Cristina Cowell 1218322
This page was medically reviewed by Dr Alexandra Cristina Cowell on February 13, 2026. Next review due on February 13, 2029.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

Provera Medroxyprogesterone acetate

Provera isn’t suitable for everyone, and there are some things you should know before taking it.

Here’s the information you need. Still concerned? Speak to our expert clinical team at any time.

Provera Medroxyprogesterone acetate

FAQ: Provera

Have something specific you want to know? Search our info below, or ask our experts a question if you can’t find what you’re looking for.

Will I get side effects from Provera?

Answer:
Like all medicines, Provera could cause side effects, but not everyone would get them. One in ten people may have experienced headaches, nausea, irregular bleeding or spotting. Some common side effects included allergic reactions, in which case it was recommended to stop taking it and inform your clinician, as well as mood changes, insomnia, anxiety, dizziness, hair loss, acne, itchiness, vaginal discharge, breast tenderness, and weight gain. If you’re concerned about any of these, let your clinician know to either change your dose or try a different treatment option.

Are there similar treatments to Provera?

Answer:
Several treatments use the same active ingredient as Provera. Depo-Provera is one, and it’s also made by the same manufacturer — except it’s an injection, not a tablet. It’s used for contraception and offers protection for eight to thirteen weeks. However, one study looked at using medroxyprogesterone acetate as an injection for menopause and found that 89.5% were relieved of symptoms compared to only 25% in the control group, suggesting that it has potential for future use for menopausal women as an alternative method. [1]

Some other treatments include combined HRT, which often uses medroxyprogesterone as one of its active ingredients. Depending on your stage of menopause, taking a continuous combined tablet may be easier for you, as you don’t have to remember to take two tablets all the time. Indivina, Premique (which is now discontinued), and Tridestra (which is also now discontinued) are all combined HRTs that use the same active ingredient as Provera but are made by different manufacturers, so their pricing and packaging may differ.

Can Provera cause weight gain?

Answer:
Weight gain was listed as one of the common side effects, and it tended to become more likely after taking it for a long time. One study looked at the link between weight gain and medroxyprogesterone, which was able to establish that the medication can cause an average 2.40kg increase in weight, especially for those who use it from a young age (for contraception). [2] Although this may seem off-putting, it’s important to remember that some patients may not experience any weight changes or even lose weight instead. Talk to your clinician if you’d like to discuss a different type of progestogen.

Do I need a prescription for Provera?

Answer:
Yes. You needed a prescription for Provera, as the prescriber would've wanted to know more about your health background to decide whether it was safe for you, and to decide which dose was right for you (usually, your starting dose would be the lowest one).

Treated trusted sources:

  1. Bullock, J. L., et al. (1975). Use of medroxyprogesterone acetate to prevent menopausal symptoms. Obstetrics and gynaecology, 46(2), pp.165–168.
  2. Sims, J., et al. (2020). Depo-medroxyprogesterone acetate, weight gain and amenorrhea among obese women adolescent and adult women. The European journal of contraception & reproductive health care : The official journal of the European Society of Contraception, 25(1), p.54.

This is healthcare on your terms.

All from the comfort of your device. Get access to what you need, when you need it.

100% online

Ask questions and get expert recommendations, at the touch of a button.

Tailored choices

We'll narrow down some treatments for you to choose from based on your medical profile.

Express delivery

Receive your treatment by secure delivery, in discreet packaging.

Repeats made easy

Set your own delivery schedule and pause or make changes any time you like.

See how it works

Get to know our clinical team

They review our info and prescribe your treatments.

Dr Daniel Atkinson

GP Clinical Lead
Dr-Daniel-Atkinson

Registered with GMC (No. 4624794)

Meet Daniel  

Ms Sanjeda Chowdhury

Superintendent Pharmacist + Independent Prescriber
Ms-Sanjeda

Registered with GPhC (No. 2202465)

Meet Sanjeda  

Mr Craig Marsh

Independent Prescriber
Mr-Craig

Registered with GPhC (No. 2070724)

Meet Craig  

Similar but different

Menopause (HRT): Here are our other options.

Blister strip of Elleste Solo tablets

Elleste Solo

Estradiol

Oestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.

£39.95
£39.95
See this option
Individual Evorel Conti patch

Evorel Conti

Estradiol/Norethisterone

Combined continuous HRT patch. Used it's been more than 12 months since your last period.

50mcg/170mcg/24hr
£47.95
£47.95
See this option
Sachet containing individual Evorel Sequi patch

Evorel Sequi

Estradiol/Norethisterone

Sequential dose patch. Use to manage menopause symptoms if you still have periods.

50mcg/24hr; 50mcg/170mcg/24hr
£47.95
£47.95
See this option
Blister strip of Femoston tablets

Femoston

Estradiol/Dydrogesterone

Comes as a continuous or sequential tablet, depending on whether you're still having periods.

£51.95
£51.95
See this option
Generic

Gina

Estradiol

Oestrogen-only HRT to tackle vaginal menopause symptoms.

10mcg
£58.95
£58.95
See this option
Dash of Duac Gel

Oestrogel

Estradiol

HRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.

0.06%
£44.95
£44.95
See this option
Generic

Progynova

Estradiol

Oestrogen only tablet or patch for women who've had a hysterectomy, or used alongside a progestogen in combined HRT.

£37.95
£37.95
See this option
Tibolone Blister Pack

Tibolone

Tibolone

Generic version of Livial. Hormone-free HRT that can improve mood and libido.

2.5mg
£33.95
£33.95
See this option
Utrogestan_Capsule

Utrogestan

Micronised progesterone

The natural progesterone treatment. Taken alongside oestrogen to relieve symptoms of menopause.

100mg
£37.95
£37.95
See this option

Here’s what you had to say

  • Service reviews
Treated
4.47

Average rating based on 2193 reviews.

Our verification process
551

Thorough start-up and lightning-fast delivery

T
551

The first 2 weeks at Mounjaro. My appetite has clearly decreased, but not completely disappeared. I can still eat, but I feel full faster and it's much easier to control portions. So far, I haven't noticed any side effects, or at least nothing serious that affects my daily life. At the moment, I'm not really focusing on my weight, but more on my body size and how my clothes fit. I clearly notice that I've lost inches: my clothes are looser and feel different. It's also the second day of my cycle now, so I'm a bit swollen. That's why I try to stay calm about the number on the scale and look more at overall progress.

I
551

Giant smooth

A
551

Clear and clear website. Easy to change adjustments. Very satisfied with Treated!

A
551

Very Satisfied

P
See all our reviews 

Read more about Provera

Further reading

Take a look at our helpful health guides related to menopause (hrt).

Woman in denim shirt holding pen

Can HRT cause cancer?

Your definitive guide. The history, science and risks: explained.…

January 24, 2024 Read more
Mature woman with hat smiling and enjoying nature.

How long after starting HRT do you feel a difference?

While most women may experience changes in their symptoms within days, many tend to notice gradual i…

February 14, 2024 Read more

Menopause at Work: 5 Symptoms and How to Get Help

Feeling supported by your employer while you’re going through the menopause can be crucial for man…

September 06, 2023 Read more
Read more articles

Give us the inbox treatment

We're making healthcare more about you. Sign up to our newsletter for personalised health articles that make a difference.

Provera isn’t available right now. But there is an alternative.
Try Utrogestan
OR Notify me
Provera isn’t available right now.
To get notified as soon as we have it, leave your name and email address below.
Get notified
Try Utrogestan

Tell us about a problem

Accept the terms of use
I'm looking for
Popular searches:
Wegovy Viagra Finasteride Varenicline Mounjaro