Sandrena is an oestrogen only hormone replacement therapy (HRT) in gel form. It’s used to treat menopausal symptoms caused by a drop in oestrogen.
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Menopause (HRT): Here are some other options.
Oestrogen-only HRT patches and pills. For if you've had a hysterectomy, or used with progestins.
Simple treatment for menopause symptoms. Estradot is a HRT patch you change just twice a week.
Sequential dose patch. Use to manage menopause symptoms if you still have periods.
Continuous combined HRT pill. Made for menopause symptoms if you haven't had a period in 1 year.
Like Kliofem, but half the dose. HRT pill that’s good if you're sensitive to hormones.
HRT gel you rub into your skin. It has an easy-to-use pump pack for menopause relief.
Combined treatment for menopause relief. Sequential pills for women who no longer have periods.
Oestrogen-only pill for menopause treatment. Same hormones as Elleste Solo, different brand.
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Disclaimer: The information provided on this page is not a substitute for professional medical advice, diagnosis, or treatment. If you have any questions or concerns about your health, please talk to a doctor.
Sandrena is an HRT treatment in gel form. It’s an oestrogen only treatment containing a hormone called estradiol. Postmenopausal women may experience uncomfortable symptoms like hot flushes in the face, neck and chest, joint pains, insomnia, or memory lapses, due to the reduced levels of oestrogen hormone in the body. Sandrena gel helps alleviate these symptoms.
Sandrena gel comes in doses of 0.5mg and 1mg, which contain estradiol 0.5mg and 1mg respectively. Estradiol is the synthetic form of oestrogen and compensates for the dropping levels of this hormone in postmenopausal women.
During menopause there is a drop in oestrogen levels in the body. This leads to various postmenopausal symptoms like hot face, neck and chest (hot flushes), joint pains, insomnia, memory lapses and reduced sex drive.
Sandrena is an alcohol based gel which contains estradiol. When you apply this gel, the alcohol evaporates and the estradiol is absorbed into the skin. The absorbed estradiol supplements the level of oestrogen and reduces the postmenopausal symptoms.
Once you start Sandrena treatment, your symptoms should start to ease within a few weeks.
Menopause is an inevitable phase of every woman’s life. But the discomfort it brings can be managed. Menopause generally happens in the age of 45 to 55 years, but in some cases it can be earlier or later.
Sandrena can be used for continuous (everyday) or cyclical (certain days throughout the month) treatment. If you still have your womb, it’s advisable to take an adequate dose of progesterone, to reduce the risk of thickening of the uterus lining (endometrium hyperplasia).
If you are postmenopausal and not using any HRT or are on a combined HRT you can start your Sandrena treatment on any day. If you are on a continuous sequential HRT regimen, you can begin this treatment on the completion of the current regimen.
Continuous transdermal oestrogen and interrupted progestogen as a novel bleed-free regimen of hormone replacement therapy for postmenopausal women. British Journal of Obstetrics and Gynaecology, 104(10), pp.1184–1190.
Guy’s and St Thomas’ NHS Foundation Trust. Hormone replacement therapy (HRT).
A comparison of transdermal and oral HRT for menopausal symptom control. International Journal of Fertility and Women’s Medicine, 51(2), pp.64–69.
Sandrena gel sachets are available in 0.5mg and 1mg. Depending on the severity of your symptoms the Sandrena gel dose recommended by your clinician may vary from 0.5mg to 1.5mg.
Based on a clinical study exploring the effectiveness of Sandrena (used alongside progesterone):
Sandrena Gel is available in 0.5mg and 1mg doses. Normally, you’ll be started off with the 0.5mg (lowest) dose to see how effective it is. If the lower dose is ineffective, it may be increased gradually, up to 1.5mg. Sensitivity of oestrogen varies for every woman, and this is taken into consideration by our clinician.
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