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Fluconazole is an effective and widely used antifungal prescription treatment.
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Fluconazole is an effective treatment designed to deal with a number of fungal infections. It can be taken differently depending on the type of infection you have. In one study comparing it with other treatment methods, infections treated with fluconazole were found to have a ‘lower recurrence rate’ .
Just like the parts of our body where we commonly find them, fungal infections come in all shapes and sizes. They’re usually nothing to worry about and can be treated simply and easily.
There are many different ways of contracting a fungal infection. Sometimes they can be caused by coming into contact with a fungus, but not always. In some situations, conditions inside the body or on the surface of the skin can provide optimal conditions for some fungi that already ‘lives’ on us to develop and thrive.
Fungal infections like vaginal thrush are nothing to do with hygiene; they’re actually the result of too much yeast being present in the vagina. Some people feel irritated and uncomfortable when experiencing infections like thrush, so they think they need to shower or bathe more often. But it’s important not to wash excessively with perfumed soaps as that might further upset the PH balance of your skin, and make the infection worse. If you think you have a fungal infection, it’s best to seek treatment for it.
There are a whole host of fungi that our bodies come into contact with on a daily basis. Some might cause ringworm, some might cause athlete’s foot, and some live harmlessly on our skin for years. It’s when conditions are right for fungus to develop that an infection occurs.
Fluconazole works by stopping a problem fungus from producing a substance called ergosterol. This is the glue that holds the fungi cells together.
Without this glue, the fungus can’t sustain itself and the infection clears up.
Interestingly, there have been studies looking at combining Fluconazole with anti-cancer drugs to enhance the effect of it . (But this has been more to investigate the effects of the anit-cancer drug than Fluconazole.)
The dosage of fluconazole you take depends on what type of fungus is causing the problem. For vaginal thrush, the recommended dose is 150mg. This is normally taken as one capsule, once a day for 7-14 days. This might be adjusted by your clinician if you have a particularly severe infection, or a persistent infection that hasn’t cleared up.
If you take Fluconazole but still have symptoms after finishing your course, you should ask your clinician for further advice.
Fluconazole 150 mg Capsules - Summary of Product Characteristics
Fluconazole 150 mg Capsules - Patient Information Leaflet (PIL) - (emc).
Repurposing the FDA-approved anticancer agent ponatinib as a fluconazole potentiator by suppression of multidrug efflux and Pma1 expression in a broad spectrum of yeast species. Microbial biotechnology, 10.1111/1751-7915.13814.
Malignant Transformation and Treatment Recommendations of Chronic Hyperplastic Candidiasis- A Six-year Retrospective Cohort Study. Mycoses, 10.1111/myc.13371.
Always take Fluconazole as your clinician has told you to.
The manufacturer leaflet says that you should go back to your clinician for help if you’ve been using Fluconazole for seven days and not seen an improvement . According to the summary of product characteristics, when you take Fluconazole it reaches ‘steady state’ in the body by day 4 or 5 . So while it only takes a few hours to be absorbed into your bloodstream, it’ll be working at close to optimum within a week.
If you miss a dose, it’s important to take that capsule as soon as you remember. If it’s nearly time for your next dose though, you should just skip the missed dose, but take your next capsule as normal. While it’s unlikely to cause you any harm, if you do accidentally take a double dose of Fluconazole, this might make you feel unwell. If this happens, you should seek medical assistance immediately.
How we source info.
When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.
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