What is Elleste Duet?
Elleste Duet is a type of sequential (or cyclical) HRT that’s typically recommended for women who have menopausal symptoms and are still experiencing their period. It contains synthetic forms of oestrogen and progesterone.
The oestrogen helps to regulate hot flushes, night sweats and other menopausal symptoms, whilst the progesterone reduces your risk of developing womb (or endometrial) cancer. [1] The oestrogen can also provide protection from osteoporosis, which can affect some women post-menopause.
How does Elleste Duet work?
The menopause causes the ovaries to produce less oestrogen, and this reduction triggers certain symptoms in the body, like trouble sleeping, lower sex drive, hot flushes, vaginal dryness and discomfort during sex, low mood and anxiety, and night sweats.
The oestrogen in combined HRT compensates for the decline in naturally occurring oestrogen in the body, and can help to ease these symptoms. It’s understood that oestrogens in HRT can reduce the frequency of menopausal symptoms by 75%. [2]
If you haven’t had a hysterectomy, the oestrogen in combined HRT can make the lining of the womb thicker than normal, and this may lead to endometrial cancer. The progesterone in Elleste Duet helps to restrict this from happening, and greatly limits the cancer risk.
And just to bring today’s science lecture to a close: the reduction in oestrogen in the body during the menopause puts the bones at greater risk of breaking or thinning. The oestrogen in combined HRT supplements this, and helps to prevent osteoporosis.
Is Elleste Duet the right HRT for me?
If you’re getting menopausal symptoms and are continuing to have periods, combined sequential HRT options like Elleste Duet and Evorel Sequi patches are usually the recommended treatments.
Like all HRT, combined sequential options can have side effects, and aren’t always suitable if you’re already taking certain medications, or if you have a particular health condition. Our clinician will assess which treatments are best for you as part of your consultation with us.
If you’re postmenopausal, continuous combined HRT options like Indivina and Evorel Conti patches are typically the best route. You usually fall into the ‘postmenopausal’ category if you’ve not had a period for one year. You take continuous combined HRT every day, without a break.
Oestrogen-only treatments such as Elleste Solo and Estradot patches are advisable for women who have had a total hysterectomy (so the whole womb including the cervix has been removed).
Different HRT products can vary from one to the next in terms of the quantity of hormones in them, so your sensitivity to hormone levels can be another important factor in which specific HRT is the right one for you.
What doses of Elleste Duet are available?
Elleste Duet is available in two doses: a low dose (1mg estradiol and 1mg norethisterone) and a medium dose (2mg estradiol and 1mg norethisterone).
You’ll usually be prescribed the lowest hormonal dose for the shortest period of time to begin with, to see how your body responds to the hormones. If you think that the hormonal dose is too low, you should discuss adjusting it with our clinician.