Compare Mounjaro with other weight loss treatments

Active ingredient
Available doses
Form
Lasts for
Made/marketed by
Pharmacy status
Prices starting at
Works in
Mounjaro

Mounjaro

Tirzepatide

Similar to Wegovy. Effective weekly weight loss injection that helps suppress your appetite.

See treatment  
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Zepbound

Zepbound

Tirzepatide

A weekly injection that works in two ways to help you lose weight.

See treatment  
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Wegovy

Wegovy

Semaglutide

Weekly injection for weight loss that works by regulating your appetite.

See treatment  
Semaglutide
0.25 mg, 0.5 mg, 1 mg, 1.7 mg, 2.4mg
Injection
Novo Nordisk
Prescription
£199.95
4 weeks
Xenical

Xenical

Orlistat

Branded version of Orlistat. It can help reduce how much fat is absorbed by the body.

See treatment  
Orlistat
120mg
Tablet
Neon Healthcare
Prescription
£61.95
1-3 months
Saxenda

Saxenda

Liraglutide

Highly effective daily injection. It interacts with your brain to make you feel more full.

See treatment  
Liraglutide
6 mg/ml
Injection
Novo Nordisk
Prescription
£86.95
2-3 weeks
Orlistat

Orlistat

Orlistat

Just like Xenical but without the branding. Can reduce fat absorption by up to 33%.

See treatment  
Orlistat
120mg
Tablet
Multiple
Prescription
£61.95
1-3 months
Mysimba

Mysimba

Buproprion + Naltrexone

A clinically proven weight loss pill. It works on receptors in the brain that control appetite.

See treatment  
Naltrexone/Bupropion
8 mg/90 mg
Tablet
Orexigen
Prescription
£143.95
8 weeks
Alli

Alli

Orlistat

A low dose version of Xenical. It reduces the amount of fat being absorbed by your body.

See treatment  
Orlistat
60mg
Tablet
GlaxoSmithKline
Pharmacy
£56.95
3-6 months
  • Manufacturers subject to change.
  • Start and duration of effects are estimations.
  • For more detailed information on your medication, read the patient information leaflet.

Is weight loss treatment right for me?

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How to choose a weight loss pill

How much we weigh can impact various aspects of our lives. It can hold us back from taking part in certain activities, make us feel unhappy or even impact our mental health. That’s why taking the decision to lose weight is a pretty big one.

Weight loss treatments can be used as part of a healthy weight loss course. However, there are several to choose from and reading up on them may feel overwhelming, especially when you’re looking for the diet pills that actually work.

We’re here to help you get a better understanding of the weight loss medication options available, so you can make the best decision for you.

How do weight loss pills work?

Weight loss pills such as Xenical, Orlistat, and Alli work by effectively creating a barrier that stops fat from being absorbed into your intestines; this fat is passed naturally, which encourages weight loss in the process.

The active ingredients in Mysimba work differently and instead act on the brain. Bupropion works to reduce your appetite and Naltrexone helps to curb food cravings so that you don’t feel the urge to eat as often.

What do diet pills do?

When diet pills are used as part of a healthy diet and exercise programme they can have a positive effect on weight loss. However, it’s not just a case of popping a pill and carrying on regardless, the user will also have to follow a diet plan to help them achieve the best results with the least amount of side effects.

When you decide to embark on a weight loss journey supported by weight loss pills your clinician will outline details of a calorie-controlled diet and a regular exercise plan. Following these instructions will help you achieve your weight loss goals. It’s recommended you speak to your physician before taking part in a high-intensity exercise programme.

Do weight loss pills work?

Licensed medicines like Mysimba and Orlistat have shown to be effective in aiding weight loss, as long as they’re used alongside a calorie controlled diet and exercise. However, how effective different weight loss medications are isn’t always directly comparable, because efficacy isn’t always measured in the same way.

Looking at the data available:

  • Clinical data for Alli found that an average of 46.7 percent of participants lost more than five percent of their weight, compared to 26.4 percent on the placebo, when taking it for six months.
  • For Orlistat, 37 percent of study participants lost at least five percent of their body weight, compared with 19 percent of those taking the placebo, when taking it for 12 weeks.
  • For Mysimba, 31 percent of participants observed a weight loss of five percent or greater, compared to the placebo group at 12 percent, when taking it for 56 weeks.
  • For Saxenda, 63.5 percent of study participants lost at least five percent of their body weight, compared to 26.6 percent in the placebo group, when taking it for 56 weeks.

Efficacy rates are a factor in what treatment you use, but they don’t necessarily decide which is best for you. One particular medicine might be better for you based on how much weight you aim to lose, or your medical history. So it’s always worth getting professional advice.

There is no magical weight loss pill that works overnight, however, if you follow the advice offered by your prescriber, and are determined to stick to your diet and exercise plan, then there are diet pills that work. There are some BMI boundaries that must be adhered to and, as previously mentioned, not all diet pills will work for everyone, but there are slimming pills that work in partnership with a diet and exercise programme to help you lose weight.

Xenical (Orlistat) - pros and cons

Clinical trials have found that following 56 weeks of treatment participants using orlistat were found to have an eight percent weight loss, versus four percent in the placebo group. However, the clinical trials also revealed that some people experience unpleasant side effects, such as fatty stools or flatulence. As Xenical is taken orally it may be favoured by users who aren’t keen on regular injections, like those used by Saxenda and Victoza which have to be regularly injected and first demonstrated by a medical professional.

Alli - pros and cons

One of the advantages of Alli is that it is available without prescription, you will still need to speak to a pharmacist before they can provide you with the treatment, but the simpler access can be viewed as a benefit to some people. Clinical trials have proven that Alli is only marginally effective in comparison to various other weight loss pills as it is given at a lower dose. Both Xenical and Orlistat are administered in larger doses and so are often more effective at reducing weight. Alli might be more suitable for those who wish to lose a smaller amount of weight. Clinical trials have also revealed that taking Alli can result in uncomfortable side effects such as uncontrollable bowel movements, oily discharge, and gas from the anus.

Saxenda - pros and cons

The active ingredient in Saxenda, liraglutide, helped trial participants consistently lose at least five to 10 percent of weight when compared to placebo. It also regulates your hunger and fullness, and stabilises your blood sugar. This can make you feel less cravings and give you better control over your eating habits. However, Saxenda is a prescription injection treatment that requires an initial demonstration by a healthcare professional. Regular injections may be off-putting to some patients. The most common side effects included nausea, diarrhoea, and vomiting.

Litramine/XLS-Medical - pros and cons

Litramine is perhaps viewed as a more gentle weight loss treatment as it can be ingested via tea, sachet, or tablet. Side effects from Litramine are mild if they occur at all. Litramine attaches itself to fat in the body and stops the fat being absorbed by the intestines. Clinical trials found it to absorb as much as 27% of dietary fats. Available without prescription.

Victoza - pros and cons

Victoza is effective at helping people with Type 2 diabetes lose weight, as it can help the body control blood sugar levels, and over a course of 56 weeks has been proven to help lose substantial weight. However, Victoza has to be injected daily, which may not be appealing to everyone, and clinical trials on its effectiveness for non-diabetic overweight people are ongoing. It can be prescribed off-label for weight loss. Victoza can cause users to experience side effects of the digestive system. Its use may be unsuitable for patients with a family history of certain cancers.

Wegovy - pros and cons

Wegovy also boasts the appeal of being a once weekly injection for weight loss. Although, the idea of self administering an injection can put some people off. The clinical trial results for Wegovy show that people lose more weight using semaglutide than when using liraglutide. Most side effects associated with Wegovy are gastrointestinal in nature, although headaches, tiredness and dizziness were also recorded. In most cases the side effects settled down quickly and didn’t stop patients from continuing with their treatment.

Mysimba - pros and cons

Mysimba will usually make you eat less food, which can cut out overeating habits and reduce your appetite. It’s also very effective. In a trial involving 1742 people, the Mysimba group lost 6.1% of their body fat, compared with 1.3% of the placebo group. There is, however, a higher risk of side effects than there is with some other weight loss treatments, and you’ll need a prescription for it before you can buy and take it.

Are there any diet pills that work fast without exercise?

We’re afraid not. There are no magical solutions to losing weight. Weight loss medication can be used alongside a balanced diet and healthy exercise routine to help boost your weight loss goals. Adopting regular exercise into your routine should be viewed as an added positive, as it will help you with your weight loss journey but also provide other health benefits too. Exercise not only helps your physical health but your mental health too.

What is the best prescription diet pill on the market?

The best prescription diet pill for you is the one that fits with your lifestyle and your goals. Important aspects you need to take into consideration are side effects, administration and prescription. What is a good prescription weight loss pill for one person may be different to another person.

A medication that works and doesn’t cause uncomfortable side effects that allows you to enjoy a healthy lifestyle alongside it is a good prescription weight loss pill.

What are the best over-the-counter weight loss pills?

Alli and XLS are the only weight loss pills available without prescription, however, it’s always recommended you speak to a professional before commencing a weight loss programme of any kind. Alli has some uncomfortable side effects and in clinical trials offers minimal assistance when losing weight. XLS is a naturally based weight loss pill, has mild side effects, can absorb as much as 27% dietary fats but again might only help you shift a few extra pounds versus dieting and exercising alone.

How to safely use weight loss medication

Choosing to start a weight loss journey may seem daunting at first. Having all the information you need can make all the difference. Read more about weight loss medication and make sure you’re on the right path from start to finish so that you can safely achieve your goals.

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This page was medically reviewed by Dr Daniel Atkinson, GP Clinical Lead on August 02, 2022. Next review due on August 02, 2024.

How we source info.

When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. Read more in our editorial policy.

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Treated

Here's how we're doing so far.

551

Treated Healthcare provides nice service. It's Efficient and reliable, highly recommend it!

551

Service extremely good with appropriate questions asked before prescribing treatment.

551

Excellent service, prompt delivery and Kliovance really helps with the menopause.

551

I am very impressed and satisfied with the team. Prompt response and fast delivery.

451

Shipping next day no arguments about that. Could do better when reordering as a mix up caused problems but sorted after return was made

551

Always arrives on time and I’m kept informed of progress.

551

I have had it previously from my G.P so It worked as expected, extremely well. My problem is an accessing my G.P practice, they put ED well down their list of priorities. I found your service excellent, quick and efficient. I fully intend to continue using it

4.9

Our average rating based on 3189 reviews.

551

Great service, prompt delivery.

551

My experience with Treated has been nothing short of exceptional. Transitioning from the US to the UK, I needed to replenish my contraceptive pill supply, and Treated made the process incredibly smooth and hassle-free. The online consultation with a doctor was convenient and reassuring. I was able to explain my requirements, and the doctor provided me with several suitable alternatives, ultimately leading me to Eloine, which has been a perfect fit for me so far. The guidance and support I received throughout the process were invaluable, and it was evident that the doctor had my best interests at heart. What truly impressed me was the speed of the entire process. Once I made my decision and completed the necessary steps, my order was promptly dispatched and arrived at my doorstep the very next day. Such efficiency is a rarity these days, and I commend Treated for their commitment to customer satisfaction. As for the product itself, I have been using Eloine for just over a week now, and I am pleased to report that everything is going well. It's comforting to know that I have access to a reliable contraceptive option that meets my needs, all thanks to Treated. I am grateful for the peace of mind they have provided me, and I will certainly be returning for any future healthcare needs. Thank you, Treated, for exceeding my expectations.

551

Easy to use, prescription dealt with quickly and medication arrived within a couple of days.

451

Bsrorge

551

Super

551

Could not have been more responsive from order and review to delivery.

551

Fast

451

Great service

551

All as requested. Very good service.

551

Gives me a great peace of mind.

551

Great

551

Fast shipping

551

shipping was not good,they kept on saying they came for delivery and couldn't find anyone I was there the whole time waiting for the delivery.

551

Good service good reminders and ordering whilst still montering your health

551

Fast and prompt as usual.

551

Excellent shipping, never had a problem. Goods arrive on time.

551

Great customer service. Reliable and honest. Highly recommend

551

Fast delivery

451

No problems experienced

551

Amazing service from Treated! Highly recommend them 👍🏽

551

5 star

451

Delivery delayed but delivered on time at next attempt

551

I've had no issues with ordering or receiving my prescription through post.

551

Great service

551

Quick and easy to use, medication delivered fast

551

Very good

551

Great easy quick service

551

Excellent service, great support thank you

551

Fast delivery and answers any questions promptly.

551

Excellent service 🙏🏾

551

Ordering was straightforward. Lots of information easy to access. Shipping was fast.

551

Brilliant

551

Excellent

551

Treats you like an adult and enables you to take your health concerns into your own hands

551

Quick and easy order, shipping and delivery

551

Brilliant

451

V.g

551

Prompt tha ks!

551

Good service

551

Reliable company

551

The best site

351

Ok but only average.

551

Prompt service

551

Treated is fab wouldnt go anywhere else for medical issues

551

Simple. Easy. Professional

551

On time

551

Good

551

Pleased with the service, very straightforward to order and delivery was very fast.

551

Everything was quick and professional

551

Shipping is speedy and the product is amazing.

551

Excellent company

551

excellent

551

Great experience 👍

551

Levothyroxine Excellent, Your Staff very helpfull, I have already recommended Treated to friends

551

Prompt, reliable service. Thank you.

551

Fantastic service.

551

Very easy process

551

Fast, efficient service

551

Great service.

551

Effortless delivery to my door

551

Fast delivery, perfect

551

Excellent service

551

Fast and secure to receive

551

Fast efficient service

551

5

551

Always on time and delivered with care

551

Very happy.thank you, fast posting, everything straight forward, well priced.will be using again.thank you.

551

Simple online assessment and swift delivery

551

Excellent service provided particularly as this is mostly out of stock in pharmacies most of the time.

551

Fast delivery

551

always efficient and prompt.

551

Fast, Courteous service.

551

The service was prompt. and my prescription arrived quickly

551

great service, thank you

551

Fast, slick service. Very easy to amend subscription when required.

551

Arrived second day coz they used royal mail instead of DPD.

551

All nice

551

All good.

551

Great service

551

Express service

551

Game changer..great service

551

Well looked after me

551

Took time to respond but was okay

551

Great

551

Efficient delivery

551

Delivered on time, received timely notification.

551

Good service

551

Medications received on time.

551

Service was spot on. So quick and helpful.

551

A good service

551

Excellent service thank-you

551

Very quick and easy service. Also a helpful team. Thanks

551

Perfect service

551

Great fast convenient service!

551

Good service. Company knows how to treat problems. Shipped when stated and delivered on time. Definitely use again.

551

Great customer service and my treatment Kilofem is the best ever - no side effects and it makes me feel young again

551

Arrived on time, well packaged.

451

Order and subscription changes are a little cumbersome. However shipping and service are A1

551

Brilliant service and very fast delivery!

551

Pleased with ordering and the treatment

551

Really helped me

551

Trusted service and great service - next day delivery and I can rely on them to send regularly.

551

Ordering was straight forward, tablets delivered promptly and well packaged, and instructions were clear, thanks.

551

100% recomended.Great service

551

Excellent service

451

fine

551

Excellent delivery. Can’t fault.

551

Quick and efficient service, delivered discreetly the next day. Thank you.

551

Effective

551

Great service, no wait time

551

Great

551

Quick assessing for medicine suitability. Quick delivery and good communication throughout.

551

Straightforward and quick service!

551

Good however communication could sometimes be better

251

Delivered on time

451

Thank you

551

Easy and good procedure to get treatment

551

Excellent product

551

Excellent service!!! Ordered what I needed sent a picture of my prescription and the parcel arrived the next day!!! Will definitely order again and have recommended to others!!!

551

Fast shipping

551

Very quick service all round

551

So quick and simple. Recommend

551

Great

551

Very convenient hassle free service.

551

Easy to use good communication and fast shipping

551

Great service

551

Efficient no issues re delivery

551

Fabulous service

551

Brilliant service. Not a bad word to say!

551

It was fast, professional and it's the right med for what I selected in there.

551

This review requires content. Oh well..

551

Great service, quite effortless.

551

Top notch

551

Brill service

551

N/a

551

Excellent service quick and easy to use

551

Fast and exact order

551

Superb service and quick delivery 10/10

551

Excellent service

451

Was ok

451

Regular & on time

551

Thank you for fast delivery

551

Shipping is extremely quick and satisfiying

551

Good stuff

551

Good service

551

Great fast delivery

551

Very good service well packaged

551

Speedy delivery great service

551

The shipping was great n received on time

551

Excellent service.

551

Excellent service

551

Had to rearrange my delivery DPD were excellent

551

The service was excellent and the shipping came just as expected without any complications. I will be using the service!!!

551

Great experience

551

Answered my questions promptly and explained what I had to do

551

Fast shipping. Great communication definitely recommend

551

First class service, shipping and no awkward tin god gatekeeping like Pharmacy4U - who couldn’t find their arse with both hands!!

551

Excellent

551

Excellent

551

Very quick and efficient

551

Good service

551

Easy and efficient

451

Very good and efficient.

551

Quick delivery and well packed , email to see how you are getting on . Cery pleased and highly recommend

551

Great company, fast delivery

551

Excellent advice and service

551

The service is excellent.

451

item arrived promptly and was well packaged! A+++

551

Good as always

551

Very pleased with this company keeps in touch with speedy delivery. Brilliant...

551

Good website, good Comms, swift delivery

551

Delivered on time great service discrete and professional.

551

Fast response

551

Extremely helpful, med on time

551

Great service

551

Excellent service & delivery

551

As stated had website problems but resolved on the phone

551

Shipping service excellent, everything is delivered in a very well protected package. I can recommend it to anyone interested. Thank you very much.

551

A good company and your prescription / treatment is monitored

551

Really great. Easy to navigate, not extortionate nor questionable like some similar services. Prescription was approved and shipped very swiftly and I would happily use this service again if necessary. Thank you.

551

Great service

551

Fast shipping, discrete packaging and good all round customer service.

551

Treated as a website is easy to navigate. The whole process/site is professional with excellent communication and speedy discreet delivery. Aftercare is included and costs are fair. Very happy.

551

Arrived on time, excellent product

551

Fast effective treatment, would highly recommend,

551

I get sent a message saying the will be dispensed and they will take the payment and the delivery time is so quick.

551

great!

551

Good communication delivered on time

551

Fantastic service

551

Brilliant

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